-
公开(公告)号：EP1539710A1
公开(公告)日：2005-06-15
申请号：EP03794956.7
申请日：2003-08-28
申请人： Bayer HealthCare AG
发明人： GIELEN-HAERTWIG, Heike , MIN-JIAN LI ,Volkhart , ROSENTRETER, Ulrich , SCHLEMMER, Karl-Heinz , ALLERHEILIGEN, Swen , TELAN, Leila , BÄRFACKER, Lars , KELDENICH, Jörg , FITZGERALD, Mary F. , NASH, Kevin , ALBRECHT, Barbara , MEURER, Dirk
IPC分类号： C07D239/40 , C07D239/38 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12 , A61K31/505 , A61K31/506 , A61P9/00 , A61P29/00
CPC分类号： C07D239/22 , C07D401/12 , C07D403/12 , C07D413/12 , C07D417/12
摘要： The invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
-
2.发明授权DIHYDROPYRIDINE DERIVATIVES FOR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS 有权FOR USE二氢吡啶衍生物作为人嗜中性粒细胞弹性蛋白酶抑制剂的
公开(公告)号：EP1537081B1
公开(公告)日：2008-10-15
申请号：EP03790905.8
申请日：2003-08-18
申请人： Bayer HealthCare AG
发明人： GIELEN-HAERTWIG, Heike , MIN-JIAN LI, Volkhart , ROSENTRETER, Ulrich , SCHLEMMER, Karl-Heinz , ALLERHEILIGEN, Swen , TELAN, Leila , BÄRFACKER, Lars , KELDENICH, Jörg , FITZGERALD, Mary, F. , NASH, Kevin , ALBRECHT, Barbara , MEURER, Dirk
IPC分类号： C07D211/90 , C07D401/04 , C07D405/04 , C07D413/04 , C07D417/04 , A61K31/4422 , A61P9/00
CPC分类号： C07D401/04 , C07D211/90 , C07D405/04 , C07D413/04 , C07D417/04
摘要： The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
-
3.发明公开DIHYDROPYRIDINE DERIVATIVES FOR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS 有权FOR USE二氢吡啶衍生物作为人嗜中性粒细胞弹性蛋白酶抑制剂的
公开(公告)号：EP1537081A1
公开(公告)日：2005-06-08
申请号：EP03790905.8
申请日：2003-08-18
申请人： Bayer HealthCare AG
发明人： GIELEN-HAERTWIG, Heike , MIN-JIAN LI, Volkhart , ROSENTRETER, Ulrich , SCHLEMMER, Karl-Heinz , ALLERHEILIGEN, Swen , TELAN, Leila , BÄRFACKER, Lars , KELDENICH, Jörg , FITZGERALD, Mary, F. , NASH, Kevin , ALBRECHT, Barbara , MEURER, Dirk
IPC分类号： C07D211/90 , C07D401/04 , C07D405/04 , C07D413/04 , C07D417/04 , A61K31/4422 , A61P9/00
CPC分类号： C07D401/04 , C07D211/90 , C07D405/04 , C07D413/04 , C07D417/04
摘要： The invention relates to novel dihydropyridine derivatives, of Formula (I) processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
-
公开(公告)号：EP1467975A1
公开(公告)日：2004-10-20
申请号：EP03704354.4
申请日：2003-01-03
申请人： Bayer HealthCare AG
发明人： ALBRECHT, Barbara , GERISCH, Michael , HÄRTER, Michael , KRAHN, Thomas , OEHME, Felix , SCHLEMMER, Karl-Heinz , STEINHAGEN, Henning
IPC分类号： C07D239/00
CPC分类号： C07D401/06 , C07D239/96 , C07D403/06 , C07D409/12 , C07D491/04 , C07D495/04
摘要： The invention relates to novel compounds of formula (I), to a method for the production thereof, and to their use as medicament active ingredients for the prophylaxis and/or treatment of diseases.
-
5.发明公开REGULATION DES APJ-REZEPTORS ZUR BEHANDLUNG ODER PROPHYLAXE VON HERZKRANKHEITEN 审中-公开APJ受体的用于治疗或预防心脏病的调控
公开(公告)号：EP1416952A1
公开(公告)日：2004-05-12
申请号：EP02764774.2
申请日：2002-07-24
申请人： Bayer HealthCare AG
CPC分类号： A61K38/1709
摘要： The invention relates to the use of APJ receptor agonists for producing a drug for the treatment and/or prophylaxis of coronary heart diseases, especially stable and unstable angina pectoris, acute myocardial infarction, myocardial infarction prophylaxis, sudden cardiac death, insufficiency of the heart, as well as high blood pressure and conditions resulting from atherosclerosis.
-
公开(公告)号：EP1812430B1
公开(公告)日：2009-04-15
申请号：EP05776232.0
申请日：2005-08-30
申请人： Bayer HealthCare AG
发明人： ERGÜDEN, Jens-Kerim , KARIG, Gunter , ROSENTRETER, Ulrich , ALBRECHT, Barbara , HENNINGER, Kerstin , HÜTTER, Joachim , DIEDRICHS, Nicole , NELL, Peter , ARNDT, Sabine , HÜBSCH, Walter , KNORR, Andreas , SCHLEMMER, Karl-Heinz , BROHM, Dirk
IPC分类号： C07D417/12 , A61K31/4439 , A61P9/12
CPC分类号： C07D417/12
摘要： The invention relates to novel phenylaminothiazole derivatives, methods for the production thereof, the use thereof for treating and/or preventing diseases, and the use thereof for producing medicaments used for treating and/or preventing diseases, preferably hypertension and other cardiovascular diseases.
-
公开(公告)号：EP1554246B1
公开(公告)日：2007-08-22
申请号：EP03790904.1
申请日：2003-08-18
申请人： Bayer HealthCare AG
发明人： GIELEN-HAERTWIG, Heike , MIN-JIAN LI, Volkhart , ROSENTRETER, Ulrich , SCHLEMMER, Karl-Heinz , ALLERHEILIGEN, Swen , TELAN, Leila , BÄRFACKER, Lars , KELDENICH, Jörg , FITZGERALD, Mary, F. , NASH, Kevin , ALBRECHT, Barbara , MEURER, Dirk
IPC分类号： C07D211/90 , C07D405/04 , C07D401/04 , C07F7/18 , A61K31/4545 , A61P29/00
CPC分类号： C07D401/04 , C07D211/90 , C07D405/04 , C07F7/1856
摘要： The invention relates to novel dihydropyridinone derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
-
8.发明公开SUBSTITUIERTE [(PHENYLETHANOYL)AMINO] BENZAMIDE UND DEREN VERWENDUNG ZUR BEHANDLUNG VON INFLAMMATORISCHEN SOWIE HERZ-KREISLAUF-ERKRANKUNGEN 审中-公开取代的[（苯基乙酰基）氨基]苯甲酰胺和它们用于治疗炎性和心血管疾病的使用
公开(公告)号：EP1814872A1
公开(公告)日：2007-08-08
申请号：EP05813330.7
申请日：2005-11-17
申请人： Bayer HealthCare AG
发明人： BRÜGGEMEIER, Ulf , GATSIOS, Petros , MEININGHAUS, Mark , TELAN, Leila , WOLTERING, Elisabeth , WUTTKE, Martina , BECK, Hartmut , GRIEBENOW, Nils , SÜSSMEIER, Frank. , KÖBBERLING, Johannes , KRETSCHMER, Axel , SVENSTRUP, Niels , BAUSER, Marcus , MORADI, Wahed , ZAISS, Siegfried , HIRTH-DIETRICH, Claudia , ALBRECHT, Barbara
IPC分类号： C07D333/60 , C07C237/42 , C07D333/24 , C07D307/81 , C07D317/60 , C07D215/12 , C07D409/12 , C07D417/12 , A61K31/381 , A61P9/00 , A61P29/00
CPC分类号： C07D307/81 , C07D215/12 , C07D317/60 , C07D333/24 , C07D333/60 , C07D409/12 , C07D417/12
摘要： The invention relates to substituted [(phenylethanoyl)amino] benzamides and to methods for the production thereof in addition to the use thereof in the production of medicaments for the treatment of and/or prophylaxis of illnesses, particularly inflammatory diseases such as diseases of the skin, respiratory passages and cardio-vascular diseases such as arteriosclerosis and coronary heart diseases.
-
公开(公告)号：EP1812430A1
公开(公告)日：2007-08-01
申请号：EP05776232.0
申请日：2005-08-30
申请人： Bayer HealthCare AG
发明人： ERGÜDEN, Jens-Kerim , KARIG, Gunter , ROSENTRETER, Ulrich , ALBRECHT, Barbara , HENNINGER, Kerstin , HÜTTER, Joachim , DIEDRICHS, Nicole , NELL, Peter , ARNDT, Sabine , HÜBSCH, Walter , KNORR, Andreas , SCHLEMMER, Karl-Heinz , BROHM, Dirk
IPC分类号： C07D417/12 , A61K31/4439 , A61P9/12
CPC分类号： C07D417/12
摘要： The invention relates to novel phenylaminothiazole derivatives, methods for the production thereof, the use thereof for treating and/or preventing diseases, and the use thereof for producing medicaments used for treating and/or preventing diseases, preferably hypertension and other cardiovascular diseases.
-
10.发明公开1,4-DIARYL-DIHYDROPYRIMIDIN-2-ONES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS 有权1,4- DIARYLDIHYDROPYRIMIDIN -2-酮及其作为人体中性粒细胞弹性的抑制剂
公开(公告)号：EP1730121A2
公开(公告)日：2006-12-13
申请号：EP05707387.6
申请日：2005-02-15
申请人： Bayer HealthCare AG
发明人： GIELEN-HÄRTWIG, Heike , ALBRECHT, Barbara , KELDENICH, Jörg , LI, Volkhart , PERNERSTORFER, Josef , SCHLEMMER, Karl-Heinz , TELAN, Leila
IPC分类号： C07D239/22 , C07D401/04 , C07D401/06 , C07D405/06 , C07D405/14 , C07D409/10 , C07D413/06 , C07D413/14 , A61K31/505 , A61K31/506 , A61P11/00
CPC分类号： C07D239/22 , C07D401/04 , C07D401/06 , C07D405/06 , C07D405/14 , C07D409/10 , C07D413/06 , C07D413/14
摘要： The invention relates to novel heterocyclic derivatives of the general formula (I), processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.019 秒)
