-
公开(公告)号：EP3655406A1
公开(公告)日：2020-05-27
申请号：EP18742977.4
申请日：2018-07-12
发明人： MOWAT, Jeffrey, Stuart , BUCHMANN, Bernd , AIGUABELLA FONT, Nuria , LEDER, Gabriele , CARRETERO, Rafael , PANKNIN, Olaf , NEUHAUS, Roland , MEIER, Robin, Michael , BERNDT, Sandra , PETERSEN, Kirstin , OFFRINGA, Rienk
IPC分类号： C07D471/04 , C07D519/00
-
公开(公告)号：EP4065584A1
公开(公告)日：2022-10-05
申请号：EP20808437.6
申请日：2020-11-24
发明人： SCHMEES, Norbert , WORTMANN, Lars , KIRCHHOFF, Dennis , NGUYEN, Thi, Thanh, Uyen , WERBECK, Nicolas , BÖMER, Ulf , PETERSEN, Kirstin , KOBER, Christina , STÖCKIGT, Detlef , LECHNER, Christian , OFFRINGA, Rienk
IPC分类号： C07D487/10 , A61K31/4375 , A61P9/00 , A61P31/12 , A61P35/00
-
公开(公告)号：EP4065574A1
公开(公告)日：2022-10-05
申请号：EP20808438.4
申请日：2020-11-24
发明人： SCHMEES, Norbert , WORTMANN, Lars , KIRCHHOFF, Dennis , NGUYEN, Thi, Thanh, Uyen , WERBECK, Nicolas , BÖMER, Ulf , PETERSEN, Kirstin , KOBER, Christina , STÖCKIGT, Detlef , LECHNER, Christian , MEIER, Robin, Michael , HERBERT, Simon, Anthony , KERSCHGENS, Isabel, Patrizia , KOSEMUND, Dirk , OFFRINGA, Rienk , GREES, Mareike
IPC分类号： C07D403/04 , A61K31/4353 , A61P35/00
-
公开(公告)号：EP4065570A1
公开(公告)日：2022-10-05
申请号：EP20808436.8
申请日：2020-11-24
发明人： SCHMEES, Norbert , WORTMANN, Lars , KIRCHHOFF, Dennis , NGUYEN, Thi, Thanh, Uyen , WERBECK, Nicolas , BÖMER, Ulf , PETERSEN, Kirstin , KOBER, Christina , STÖCKIGT, Detlef , LECHNER, Christian , MEIER, Robin, Michael , HERBERT, Simon, Anthony , KERSCHGENS, Isabel, Patrizia , KOSEMUND, Dirk , LEFRANC, Julien , OFFRINGA, Rienk
IPC分类号： C07D401/04 , C07D403/14 , C07D405/14 , A61K31/4709 , A61P31/12 , A61P9/00 , A61P35/00
-
公开(公告)号：EP3638669A1
公开(公告)日：2020-04-22
申请号：EP18728901.2
申请日：2018-06-07
申请人： Bayer Pharma Aktiengesellschaft , Deutsches Krebsforschungszentrum Heidelberg , Bayer Aktiengesellschaft
发明人： BUCHMANN, Bernd , SCHMEES, Norbert , MOWAT, Jeffrey Stuart , LEDER, Gabriele , PANKNIN, Olaf , CARRETERO, Rafael , AIGUABELLA FONT, Nuria , BRIEM, Hans , FRIBERG, Anders Roland , HUSEMANN, Manfred , BÖMER, Ulf , STÖCKIGT, Detlef , NEUHAUS, Roland , BERNDT, Sandra , PETERSEN, Kirstin , OFFRINGA, Rienk
IPC分类号： C07D471/04 , A61P35/00
-
公开(公告)号：EP4139287A1
公开(公告)日：2023-03-01
申请号：EP21720251.4
申请日：2021-04-20
发明人： SCHMEES, Norbert , ROEHN, Ulrike , KIRCHHOFF, Dennis , PETERSEN, Kirstin , NGUYEN, Thi, Thanh, Uyen , GREES, Mareike , WERBECK, Nicolas , BOEMER, Ulf , BADER, Benjamin , STOECKIGT, Detlef , OFFRINGA, Rienk , LINK, Corinna , TESTOLIN, Giambattista , NOWAK-REPPEL, Katrin
IPC分类号： C07D277/38 , C07D417/06 , C07D417/10 , A61K31/426 , A61K31/4439 , A61P37/06
-
公开(公告)号：EP4139286A1
公开(公告)日：2023-03-01
申请号：EP21720249.8
申请日：2021-04-20
发明人： SCHMEES, Norbert , ROEHN, Ulrike , KIRCHHOFF, Dennis , PETERSEN, Kirstin , NGUYEN, Thi, Thanh, Uyen , GREES, Mareike , WERBECK, Nicolas , BOEMER, Ulf , BADER, Benjamin , STOECKIGT, Detlef , KOSEMUND, Dirk , OFFRINGA, Rienk , LINK, Corinna , NOWAK-REPPEL, Katrin
IPC分类号： C07D277/38 , C07D417/06 , C07D417/10 , A61K31/426 , A61K31/4439 , A61P37/06
-
公开(公告)号：EP3781565A1
公开(公告)日：2021-02-24
申请号：EP19720074.4
申请日：2019-04-15
发明人： WORTMANN, Lars , SAUTIER, Brice , EIS, Knut , BRIEM, Hans , BÖHNKE, Niels , VON NUSSBAUM, Franz , HILIG, Roman , BADER, Benjamin , SCHRÖDER, Jens , PETERSEN, Kirstin , LIENAU, Philip , WENGNER, Antje, Margret , MOOSMAYER, Dieter , WANG, Qiuwen
IPC分类号： C07D471/04 , A61K31/519 , A61P35/00
-
公开(公告)号：EP3356373A1
公开(公告)日：2018-08-08
申请号：EP16770510.2
申请日：2016-09-26
发明人： LÜCKING, Ulrich , GEISLER, Jens , HOG, Daniel , SCHOLZ, Arne , PETERSEN, Kirstin , LIENAU, Philip , STEGMANN, Christian , ANDRES, Dorothee , ZHENG, Kunzeng , GAO, Ping , CHEN, Gang , XI, Jiajun , HERBERT, Simon Anthony , SIEMEISTER, Gerhard , WERBECK, Nicolas
IPC分类号： C07D498/04 , A61K31/4375 , A61K31/519 , C07D498/14 , A61P35/00 , A61P31/00 , A61P9/00
摘要： The present invention relates to novel macrocyclic sulfondiimine compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).
-
10.发明公开6-HYDROXYBENZOFURANYL- AND 6-ALKOXYBENZOFURANYL-SUBSTITUTED IMIDAZOPYRIDAZINES 审中-公开6-羟基苯并呋喃-2-基和6-烷氧基苯并呋喃基取代的咪唑并哒嗪
公开(公告)号：EP3237417A1
公开(公告)日：2017-11-01
申请号：EP15817825.1
申请日：2015-12-21
发明人： EIS, Knut , HARTUNG, Ingo , PETERSEN, Kirstin , LIENAU, Philip , BÖMER, Ulf
IPC分类号： C07D487/04 , A61K31/5025 , A61P35/00 , A61P37/00
CPC分类号： C07D487/04 , A61K31/5025 , A61K31/5377 , A61K45/06
摘要： The present invention relates to 6-hydroxybenzofuranyl- and 6-alkoxybenzofuranyl- substituted imidazopyridazine compounds of general formula (I) in which R1 and R2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
摘要翻译： 本发明涉及通式（I）的6-羟基苯并呋喃基和6-烷氧基苯并呋喃基取代的咪唑并哒嗪化合物，其中R 1和R 2如权利要求中所定义，涉及制备所述化合物的方法，涉及用于制备所述化合物的中间体化合物 ，涉及包含所述化合物的药物组合物和组合以及涉及所述化合物用于制备用于治疗或预防疾病，特别是过度增殖和/或血管生成失调的药物组合物作为唯一药物或组合 与其他有效成分。
-
-
-
-
-
-
-
-
-
搜索结果
29 条记录 (耗时 0.016 秒)
