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1.发明授权
公开(公告)号：EP3221000B1
公开(公告)日：2019-01-09
申请号：EP15798056.6
申请日：2015-11-19
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2.发明公开
公开(公告)号：EP3221000A1
公开(公告)日：2017-09-27
申请号：EP15798056.6
申请日：2015-11-19
申请人： CHAMBRE DE COMMERCE ET D'INDUSTRIE DE REGION PARIS ILE DE FRANCE (ESIEE PARIS) , Institut National de la Santé et de la Recherche Médicale (INSERM) , Université Pierre et Marie Curie (Paris 6) , Centre National de la Recherche Scientifique (CNRS)
CPC分类号： A61N1/05 , A61N1/025 , A61N1/0543 , A61N1/36 , H05K3/06 , H05K3/4682 , H05K2201/0154
摘要： The invention relates to a process for manufacturing at least one implant for focal electrical stimulation of a nervous structure, said implant being of the type including in a supporting structure a network of cavities (3) at the bottom of which are placed microelectrodes (4), the cavities (3) being bounded by walls (3a) erected and located around the microelectrodes (4), the supporting structure being produced beforehand by implementing the following steps: deposition and etching, in a planar manner, on an insulating substrate (10, 11), of electrical contacts (7), of electrical tracks (6a, 6b) and of microelectrodes (4), first tracks (6a) electrically connecting the microelectrodes (4) and the electrical contacts (7), second electrical tracks (6b) being electrically connected to a ground.
摘要翻译： 本发明涉及一种用于制造用于神经结构的局部电刺激的至少一个植入物的方法，所述植入物的类型包括在支撑结构中的腔体网络（3），其底部放置微电极（4） ，所述空腔（3）由竖立并位于所述微电极（4）周围的壁（3a）围成，所述支撑结构通过实施以下步骤预先制造：以平面方式沉积和蚀刻在绝缘基底（10 （6）和微电极（4）的电触头（7），电连接微电极（4）和电触头（7）的第一轨道（6a），第二电轨道 6b）电连接到地。
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3.发明公开
公开(公告)号：EP2566573A1
公开(公告)日：2013-03-13
申请号：EP11723540.8
申请日：2011-04-29
发明人： LORACH, Henri , DJILAS, Milan , YVERT, Blaise , BERGONZO, Philippe , LISSORGUES, Gaelle , ROUSSEAU, Lionel , BENOSMAN, Ryad, Benjamin , PICAUD, Serge , SAHEL, José , IENG, Siohoi
CPC分类号： A61N1/0553 , A61N1/025 , A61N1/05 , A61N1/37205
摘要： The invention relates to an implant which includes, in order to electrically stimulate a nerve structure, in particular the retina, an electrically insulating substrate (1), a network of recesses (2) formed in an upper surface of the substrate, stimulation electrodes (3) arranged at the bottom of the recesses, and an electrically conductive layer forming a floorplan (4) at the upper portion of the recesses. The sizes of the recesses and of the electrodes of the implant are such that the spatial selectivity of the stimulation current applied to the nerve structure are maximised.
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4.发明授权
公开(公告)号：EP2566573B1
公开(公告)日：2015-07-29
申请号：EP11723540.8
申请日：2011-04-29
发明人： LORACH, Henri , DJILAS, Milan , YVERT, Blaise , BERGONZO, Philippe , LISSORGUES, Gaelle , ROUSSEAU, Lionel , BENOSMAN, Ryad, Benjamin , PICAUD, Serge , SAHEL, José , IENG, Siohoi
IPC分类号： A61N1/02
CPC分类号： A61N1/0553 , A61N1/025 , A61N1/05 , A61N1/37205
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公开(公告)号：EP3158071A1
公开(公告)日：2017-04-26
申请号：EP15732868.3
申请日：2015-06-12
发明人： PERSILLON, Cécile , ULLMANN, Christophe , AYRINHAC, Céline , BONZOM, Olivier , FORT, Sébastien , ARMAND, Sylvie , PRADEAU, Stéphanie , MARGEOT, Antoine , ROUSSEAU, Lionel , LE ROUX, Françoise
IPC分类号： C12N15/80
CPC分类号： C12N9/2437 , C12N9/2405 , C12P7/10 , C12Y302/01091 , Y02E50/16
摘要： The present invention relates to the expression and optimisation of enzymes involved in the breakdown of lignocellulosic biomass. The present invention specifically relates to variants of the exoglucanase 1 of
Trichoderma reesei , as well as to the use of said variants with improved efficiency in methods for breaking down cellulose and for producing biofuel.摘要翻译： 本发明涉及涉及木质纤维素生物质分解的酶的表达和优化。 本发明具体涉及里氏木霉的外切葡聚糖酶1的变体，以及所述变体在用于分解纤维素和生产生物燃料的方法中具有提高的效率的用途。
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6.发明公开DISPOSITIF DE STIMULATION D'UN TISSU VIVANT PAR MICROELECTRODES, SES MODULE AMOVIBLE ET UTILISATION 有权装置中由微电极和可移动模块，并使用LIVE组织的刺激
公开(公告)号：EP2217322A1
公开(公告)日：2010-08-18
申请号：EP08842542.6
申请日：2008-10-20
申请人： Centre National de la Recherche Scientifique (CNRS) , Groupe Ecole Superieure D'ingenieurs En Electronique Et Electrotechnique , Université Bordeaux 1
CPC分类号： A61N1/36185 , A61B5/04 , A61B2562/0209 , A61B2562/046 , A61N1/05 , A61N1/0541 , A61N1/0543 , A61N1/0551 , A61N1/36017 , A61N1/36071
摘要： The invention relates to a device for stimulating living tissue, comprising an array (1) of stimulating microelectrodes (11) that are placed in a defined configuration side by side and able to be selected by applying an electrical signal for stimulation by one of the microelectrodes. According to the invention, an additional conducting surface (3) for application against the living tissue, is provided in the vicinity of a defined plurality of sections (210) for local application of microelectrodes (11), connecting means (32) being provided for electrical connection between the zones (31), and the additional conducting surface (3) being also connected to a lead (33) and being formed so as to ensure local stimulation via a microelectrode (11).
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7.发明授权DISPOSITIF DE STIMULATION D'UN TISSU VIVANT PAR MICROELECTRODES, SES MODULE AMOVIBLE ET UTILISATION 有权装置中由微电极和可移动模块，并使用LIVE组织的刺激
公开(公告)号：EP2217322B1
公开(公告)日：2013-08-21
申请号：EP08842542.6
申请日：2008-10-20
申请人： Centre National de la Recherche Scientifique (CNRS) , Groupe Ecole Superieure D'ingenieurs En Electronique Et Electrotechnique , Université Bordeaux 1
CPC分类号： A61N1/36185 , A61B5/04 , A61B2562/0209 , A61B2562/046 , A61N1/05 , A61N1/0541 , A61N1/0543 , A61N1/0551 , A61N1/36017 , A61N1/36071
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