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公开(公告)号：EP3390637A1
公开(公告)日：2018-10-24
申请号：EP16876828.1
申请日：2016-12-16
发明人： MILLER, Chris , NEGRETE-RAYMOND, Ana , VELDHOUSE, Jon , VAS, Amit , RUSH, Brian
摘要： Genetically modified yeast having a heterologous sugar transporter that is capable of transporting a non-glucose sugar such as maltulose, are described. The heterologous sugar transporter can be a protein according to, or that has similarity to, SEQ ID NO:44. Fermentation methods using enzymatically treated starch where the yeast are able to consume the non-glucose sugars, are also described. The engineered yeast can be useful for producing desired bioproducts such as high ethanol, with low amounts of residual sugars in the medium.
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2.发明公开MODIFIED GLUCOAMYLASE ENZYMES AND YEAST STRAINS HAVING ENHANCED BIOPRODUCT PRODUCTION 审中-公开修饰的葡糖淀粉酶和酵母菌株具有增强的生物产量生产
公开(公告)号：EP3253779A1
公开(公告)日：2017-12-13
申请号：EP16706708.1
申请日：2016-02-05
IPC分类号： C07K14/395 , C12N9/34
CPC分类号： C12N9/2428 , C07K14/395 , C07K2319/02 , C12N9/16 , C12P19/14 , C12Y301/03002
摘要： The invention is directed to non-natural yeast able to secrete significant amounts of glucoamylase into a fermentation media. The glucoamylase can promote degradation of starch material generating glucose for fermentation to a desired bioproduct, such as ethanol. The glucoamylase can be provided in the form of a glucoamylase fusion protein having a S. cerevisiae mating factor alpha 2 (Sc MFα2) or repressible acid phosphatase (Sc PHO5) secretion signal.
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3.发明公开
公开(公告)号：EP3494129A1
公开(公告)日：2019-06-12
申请号：EP17837760.2
申请日：2017-08-04
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公开(公告)号：EP3625340A1
公开(公告)日：2020-03-25
申请号：EP18802133.1
申请日：2018-05-18
发明人： FINLEY, Kenneth R. , KOZLOWICZ, Briana , NEGRETE-RAYMOND, Ana , POYNTER, Gregory M. , VAS, Amit
IPC分类号： C12N15/09 , C12N15/74 , C12N15/63 , C12N15/113 , C12N9/22 , C07K14/195
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5.发明公开GLUCOAMYLASE-MODIFIED YEAST STRAINS AND METHODS FOR BIOPRODUCT PRODUCTION 审中-公开葡糖淀粉酶修饰的酵母菌株和用于生产生产的方法
公开(公告)号：EP3274461A1
公开(公告)日：2018-01-31
申请号：EP16718536.2
申请日：2016-03-25
CPC分类号： C12N15/81 , C12P7/10 , C12Y302/01003 , Y02E50/16 , Y02E50/17
摘要： Genetically engineered yeast with a heterologous glucoamylase and fermentation methods are described. The engineered yeast can have multiple exogenous nucleic acid sequences which each have a different sequence, but that encode the same or a similar glucoamylase protein that is heterologous to the yeast. The engineered yeast exhibit desirable bioproduct production profiles during a fermentation process. A fermentation medium with a starch material can be fermented with the engineered yeast to provide high ethanol titers, low glycerol titers, or both.
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