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1.发明公开
公开(公告)号：EP1432726A2
公开(公告)日：2004-06-30
申请号：EP02770481.6
申请日：2002-09-09
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , BURGESS, Catherine, E. , EDINGER, Shlomit, R. , GERLACH, Valerie, L. , LEPLEY, Denise, M. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , TAUPIER, Raymond, J., Jr. , ZHONG, Mei
IPC分类号： C07K1/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K2319/00
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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2.发明公开
公开(公告)号：EP1399537A2
公开(公告)日：2004-03-24
申请号：EP02726701.2
申请日：2002-04-03
申请人： Curagen Corporation
发明人： LI, Li , GERLACH, Valerie , LIU, Xiaohong , MILLER, Charles, E. , SPYTEK, Kimberly, A. , ZERHUSEN, Bryan, D. , PENA, Carol, E., A. , SHENOY, Suresh, G. , ZHONG, Haihong , SMITHSON, Glennda , CASMAN, Stacie, J. , BOLDOG, Ferenc, L. , VOSS, Edward, Z. , VERNET, Corine, A., M. , MACDOUGALL, John, R. , RASTELLI, Luca , ANDERSON, David, W. , ZHONG, Mei , MEZES, Peter, S. , FURTAK, Katarzyna , PATTURAJAN, Meera , BURGESS, Catherine E. , MALYANKAR, Uriel M. , SHIMKETS, Richard A. , TAUPIER, Raymond J., Jr. , EDINGER, Shlomit R. , MAZUR, Ann
IPC分类号： C12N1/00
CPC分类号： C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：EP1385953A2
公开(公告)日：2004-02-04
申请号：EP01993275.5
申请日：2001-12-10
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BURGESS, Catherine, E. , BOLDOG, Ferenc, L. , CASMAN, Stacie, J. , COLMAN, Steven, D. , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie , GORMAN, Linda , GROSSE, William, M. , GUO, Xiaojia , HERRMANN, John, L. , KEKUDA, Ramesh , LEPLEY, Denise, M. , LI, Li , MACDOUGALL, John, R. , MILLET, Isabelle , PENA, Carol, E., A. , PEYMAN, John A. , RASTELLI, Luca , RIEGER, Daniel K. , SHIMKETS, Richard A. , SMITHSON, Glennda , SPYTEK, Kimberly A. , STONE, David J. , TCHERNEV, Velizar T. , VERNET, Corine A.M. , VOSS, Edward Z. , ZERHUSEN, Bryan D. , ZHONG, Haihong , ZHONG, Mei
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , G01N33/53 , C12Q1/68 , G01N33/68 , G01N33/50 , A61K38/17 , A61K48/00 , A61K39/395
CPC分类号： G01N33/57484 , A61K38/00 , C07K14/47 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , G01N33/574 , G01N33/6893 , G01N33/6896 , G01N2500/00
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further disclose therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.
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公开(公告)号：EP1383533A2
公开(公告)日：2004-01-28
申请号：EP02723842.7
申请日：2002-04-11
发明人： PENA, Carol, E., A. , GUO, Xiaojia , SHIMKETS, Richard, A. , PADIGARU, Muralidhara , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , MEHRABAN, Fuad , TOPPER, James, N. , MALYANKAR, Uriel, M. , WASSERMAN, Scott , EDINGER, R. Shlomit , SMITHSON, Glennda , GUNTHER, Erik , KOMUVES, Laszlo
IPC分类号： A61K39/00
CPC分类号： C07K14/47
摘要： Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
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5.发明公开NOVEL ANTIBODIES THAT BIND TO ANTIGENIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING THE ANTIGENS, AND METHODS OF USE 审中-公开新抗体的抗基因多肽结合抗基因编码核酸及使用方法
公开(公告)号：EP1401470A2
公开(公告)日：2004-03-31
申请号：EP02732027.4
申请日：2002-06-04
申请人： Curagen Corporation
发明人： ANDERSON, David, W. , ZERHUSEN, Bryan, D. , LI, Li , ZHONG, Mei , CASMAN, Stacie, J. , GERLACH, Valerie, L. , SHIMKETS, Richard, A. , GORMAN, Linda , PENA, Carol, E., A. , KEKUDA, Ramesh , PATTURAJAN, Meera , SPYTEK, Kimberly, A. , LEITE, Mario, W. , RASTELLI, Luca , MACDOUGALL, John, R. , TAUPIER, Raymond, J., Jr. , GUO, Xiaojia , MILLER, Charles, E. , SHENOY, Suresh, G. , HJALT, Tord , VOSS, Edward Z. , BOLDOG, Ferenc L. , MALYANKAR, Uriel M. , PADIGARU, Muralidhara , JI, Weizhen , SMITHSON, Glennda , EDINGER, Shlomit R. , MILLET, Isabelle , ELLERMAN, Karen
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
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6.发明公开
公开(公告)号：EP1379554A2
公开(公告)日：2004-01-14
申请号：EP02739088.9
申请日：2002-02-21
申请人： Curagen Corporation
发明人： PENA, Carol, E., A. , SHIMKETS, Richard, A. , LI, Li , SHENOY, Suresh, G. , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , VERNET, Corine, A., M. , MALYANKAR, Uriel, L. , GUO, Xiaojia , GUSEV, Vladimir, Y. , CASMAN, Stacie, J. , BOLDOG, Ferenc, L. , FURTAK, Katarzyna , TCHERNEV, Velizar, T. , PATTURAJAN, Meera , GANGOLLI, Esha, A. , PADIGARU, Muralidhara , LIU, Xiaohong , BAUMGARTNER, Jason, C. , GERLACH, Valerie L. , SPADERNA, Steven K. , ZERHUSEN, Bryan D.
IPC分类号： C07K14/47 , C12N15/12 , C12N5/10 , C07K16/18 , G01N33/53 , G01N33/50 , A61K48/00 , A61K31/713
CPC分类号： G05B19/408 , A61K31/713 , A61K38/00 , A61K48/00 , C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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7.发明公开
公开(公告)号：EP1513864A2
公开(公告)日：2005-03-16
申请号：EP03710863.6
申请日：2003-02-03
申请人： Curagen Corporation
发明人： ANDERSON, David, W. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , GORMAN, Linda , JI, Weizhen , KEKUDA, Ramesh , LI, Li , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr.
IPC分类号： C07K1/00 , C07K14/00 , C07K16/00 , C07K17/00 , G01N33/53 , C12P21/06 , C12N15/00 , C12N15/09 , C12N15/63
CPC分类号： C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
摘要翻译： 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体，以及对多肽特异的新多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。
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公开(公告)号：EP1409679A2
公开(公告)日：2004-04-21
申请号：EP02715003.6
申请日：2002-02-26
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BALLINGER, Robert A. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , ELLERMAN, Karen, E. , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GILBERT, Jennifer, A. , GORMAN, Linda , GUO, Xiaojia , GUSEV, Vladimir, Y. , KEKUDA, Ramesh , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , PEYMAN, John, A. , RASTELLI, Luca , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SMITHSON, Glennda , SPYTEK, Kimberly, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr. , TCHERNEV, Velizar, T. , VERNET, Corine, A., M. , ZERHUSEN, Bryan, D.
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , C12Q1/68 , A61K38/17 , A61P3/00 , A61P21/00 , A61P3/10 , A61K39/395 , G01N33/68
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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9.发明公开THERAPEUTIC POLYPEPTIDES, NUCLEIC ACIDS ENCODING SAME, AND METHODS OF USE 审中-公开治疗性多肽，核酸对这种字符，和方法的应用
公开(公告)号：EP1401858A2
公开(公告)日：2004-03-31
申请号：EP02739617.5
申请日：2002-06-04
申请人： Curagen Corporation
发明人： ANDERSON, David, W. , BAUMGARTNER, Jason, C. , BOLDOG, Ferenc, L. , CASMAN, Stacie, J. , EDINGER, Schlomit, R. , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , HJALT, Tord , KEKUDA, Ramesh , LI, Li , MACDOUGALL, John, R. , MALYANKAR, Uriel, M. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , RASTELLI, Luca , SHIMKETS, Richard A. , STONE, DAVID J. , SPYTEK, Kimberly A. , VERNET, Corine A.M. , VOSS, Edward Z. , ZERHUSEN, Bryan D.
IPC分类号： C07K1/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00
摘要： Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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10.发明公开NOVEL HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开新的人类蛋白质，多核苷酸编码本而方法
公开(公告)号：EP1401486A2
公开(公告)日：2004-03-31
申请号：EP02732026.6
申请日：2002-06-04
申请人： Curagen Corporation
发明人： ZERHUSEN, Bryan, D. , KEKUDA, Ramesh , SPYTEK, Kimberly, A. , SHENOY, Suresh, G. , MILLER, Charles, E. , HJALT, Tord , GERLACH, Valerie, L. , BAUMGARTNER, Jason, C. , GUO, Xiaojia , GANGOLLI, Esha, A. , VERNET, Corine, A., M. , PADIGARU, Muralidhara , LI, Li , PENA, Carol, E., A. , GORMAN, Linda , ANDERSON, David, W. , EDINGER, Shlomit, R. , PATTURAJAN, Meera , STONE, David, J.
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K39/00 , A61K48/00
摘要： Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
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