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公开(公告)号：EP1385953A2
公开(公告)日：2004-02-04
申请号：EP01993275.5
申请日：2001-12-10
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BURGESS, Catherine, E. , BOLDOG, Ferenc, L. , CASMAN, Stacie, J. , COLMAN, Steven, D. , EDINGER, Shlomit, R. , ELLERMAN, Karen , GERLACH, Valerie , GORMAN, Linda , GROSSE, William, M. , GUO, Xiaojia , HERRMANN, John, L. , KEKUDA, Ramesh , LEPLEY, Denise, M. , LI, Li , MACDOUGALL, John, R. , MILLET, Isabelle , PENA, Carol, E., A. , PEYMAN, John A. , RASTELLI, Luca , RIEGER, Daniel K. , SHIMKETS, Richard A. , SMITHSON, Glennda , SPYTEK, Kimberly A. , STONE, David J. , TCHERNEV, Velizar T. , VERNET, Corine A.M. , VOSS, Edward Z. , ZERHUSEN, Bryan D. , ZHONG, Haihong , ZHONG, Mei
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , G01N33/53 , C12Q1/68 , G01N33/68 , G01N33/50 , A61K38/17 , A61K48/00 , A61K39/395
CPC分类号： G01N33/57484 , A61K38/00 , C07K14/47 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , C12Q2600/16 , G01N33/574 , G01N33/6893 , G01N33/6896 , G01N2500/00
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further disclose therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.
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公开(公告)号：EP1360291A2
公开(公告)日：2003-11-12
申请号：EP01973124.9
申请日：2001-09-17
申请人： Curagen Corporation
发明人： MISHRA, Vishnu, S. , SPYTEK, Kimberly, Ann , TAUPIER, Raymond, J., Jr. , VERNET, Corine, A., M. , COLMAN, Steven, D. , GORMAN, Linda , TCHERNEV, Velizar, T. , MALYANKAR, Uriel, M. , SHENOY, Suresh , TCHERNEV, Velizar, T. , PADIGARU, Muralidhara , SMITHSON, Glennda , MILLET, Isabelle , PEYMAN, John, A. , STONE, David , GUNTHER, Erik , ELLERMAN, Karen , GERLACH, Valerie L. , LI, Li , ZERHUSEN, Bryan D. , MACDOUGAL, John R. , RASTELLI, Luca
IPC分类号： C12N15/12
CPC分类号： A61B10/0275 , A61B2010/0208 , A61B2017/00398 , C07K14/475 , C07K14/5425 , C07K14/705 , C07K14/70571
摘要： Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatibility complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：EP1409681A2
公开(公告)日：2004-04-21
申请号：EP02784815.9
申请日：2002-01-31
申请人： Curagen Corporation
发明人： TCHERNEV, Velizar, T. , SPYTEK, Kimberly, A. , ZERHUSEN, Bryan, D. , PATTURAJAN, Meera , SHIMKETS, Richard, A. , LI, Li , GANGOLLI, Esha, A. , PADIGARU, Muralidhara , ANDERSON, David, W. , RASTELLI, Luca , MILLER, Charles, E. , GERLACH, Valerie, L. , TAUPIER, Raymond, J., Jr. , GUSEV, Vladimir, Y. , COLMAN, Steven, D. , WOLENC, Adam, R.c/o CuraGen Corporation , PENA, Carol, E., A.c/o CuraGen Corporation , FURTAK, Katarzyna , GROSSE, William, M. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , RIEGER, Daniel, K. , BURGESS, Catherine, E.
IPC分类号： C12N15/12 , C12N1/21 , C07K14/47 , C07K14/705 , C07K16/18
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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4.发明公开
公开(公告)号：EP1572922A2
公开(公告)日：2005-09-14
申请号：EP03726032.0
申请日：2003-03-06
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CHAUDHURI, Amitabha , COLMAN, Steven, D. , EDINGER, Shlomit, R. , ETTENBERG, Seth , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GORMAN, Linda , GUO, Xiaojia , KEKUDA, Ramesh , LI, Li , MACLACHLAN, Timothy , MALYANKAR, Uriel, M. , MEZES, Peter, S. , MILLER, Charles, E. , MILLET, Isabelle , PATTURAJAN, Meera , PEYMAN, John
IPC分类号： C12N1/00
摘要： The present invention relates to novel polypeptides, and the nucleic acids encoding them, having properties related to stimulation of biochemical or physiological responses in a cell, a tissue, an organ or an organism. More particularly, the novel polypeptides are gene products of novel genes, or are specified biologically active fragments or derivatives thereof. Methods of use encompass diagnostic and prognostic assay procedures as well as methods of treating diverse pathological conditions.
摘要翻译： 本发明涉及新的多肽和编码它们的核酸，其具有与刺激细胞，组织，器官或生物体中的生化或生理反应有关的性质。 更具体地说，新多肽是新基因的基因产物，或者是特定的生物活性片段或衍生物。 使用方法包括诊断和预后测定程序以及治疗不同病理状况的方法。
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公开(公告)号：EP1366162A2
公开(公告)日：2003-12-03
申请号：EP01996122.6
申请日：2001-12-06
申请人： Curagen Corporation
发明人： GUO, Xiaojia , LI, Li , PATTURAJAN, Meera , SHIMKETS, Richard, A. , CASMAN, Stacie, J. , MALYANKAR, Uriel, M. , TCHERNEV, Velizar, T. , VERNET, Corinne, A.M. , SPYTEK, Kimberly A. , SHENOY, Suresh, G. , ALSOBROOK, John, P., II , EDINGER, Schlomit , PEYMAN, John, A. , STONE, David, J. , ELLERMAN, Karen , GANGOLLI, Esha, A. , BOLDOG, Ferenc, L. , COLMAN, Steven, D. , EISEN, Andrew, J. , LIU, Xiaohong , PADIGARU, Muralidhara , SPADERNA, Steven K. , ZERHUSEN, Bryan D.
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , C12Q1/68 , G01N33/53 , G01N33/50 , G01N33/68 , A61K38/17 , A61K48/00 , A61K39/395
摘要： Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
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6.发明公开
公开(公告)号：EP1370659A2
公开(公告)日：2003-12-17
申请号：EP02761846.1
申请日：2002-01-16
申请人： Curagen Corporation
发明人： PADIGARU, Muralidhara , ALSOBROOK, John, P., II , COLMAN, Steven, D. , SPYTEK, Kimberly, A. , BOLDOG, Ferenc , VERNET, Corine, A., M. , LI,Li , SHENOY, Suresh , CASMAN, Stacie , GUO, Xiaojia , EDINGER, Shlomit , MACDOUGALL, John , MALYANKAR, Uriel, M. , PATTURAJAN, Meera , SHIMKETS, Richard, A. , PENA, Carol , TCHERNEV, Velizar , ZERHUSEN, Bryan, D. , MILLET, Isabelle , MILLER, Charles, E. , LEPLEY, Denise, M. , SMITHSON, Glennda , BAUMGARTNER, Jason , HERRMANN, John , PEYMAN, John, A. , GORMAN, Linda , MEZES, Peter , MEZES, Peter , TAUPIER, Raymond, J., Jr. , GERLACH, Valerie , GROSSE, William, M. , LIU, Xiaohong , ELLERMAN, Karen , ROTHENBERG, Mark , STONE, David, J. , BURGESS, Catherine, E. , KEKUDA, Ramesh
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.
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7.发明公开HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME 审中-公开人类蛋白质，多核苷酸编码它们的和使用方法
公开(公告)号：EP1356047A2
公开(公告)日：2003-10-29
申请号：EP01989235.5
申请日：2001-12-17
申请人： Curagen Corporation
发明人： SHIMKETS, Richard, A. , COLMAN, Steven, D. , SPYTEK, Kimberly, A. , BALLINGER, Robert, A. , GUO, Xiaojia , TCHERNEV, Velizar, T. , SHENOY, Suresh, G. , LI, Li , ELLERMAN, Karen, E. , ZERHUSEN, Bryan, D. , PATTURAJAN, Meera , CASMAN, Stacie, J. , BOLDOG, Ferenc , GUSEV, Vladimir, Y. , BURGESS, Catherine, E. , EDINGER, Schlomit , GANGOLLI, Esha, A. , MALYANKAR, Uriel, M. , GUNTHER, Erik , SMITHSON, Glennda , MILLET, Isabelle , GERLACH, Valerie L.
IPC分类号： C12N15/12 , C07K14/47 , C07K14/705 , C07K14/485 , C07K14/81 , C12N9/02 , C07K16/18 , G01N33/53 , G01N33/68 , A61K38/17 , A61K39/00 , C12Q1/68
摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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