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1.发明公开
公开(公告)号：EP1443913A2
公开(公告)日：2004-08-11
申请号：EP02807153.8
申请日：2002-07-03
申请人： Curagen Corporation
发明人： LI, Li , SHENOY, Suresh, G. , PATTURAJAN, Meera , ELLERMAN, Karen , GORMAN, Linda , ZHONG, Mei , CATTERTON, Elina , SPYTEK, Kimberly, A. , MILLER, Charles, E. , EDINGER, Shlomit, R. , HJALT, Tord , GERLACH, Valerie, L. , SHIMKETS, Richard, A. , TAUPIER, Raymond, J., Jr. , ANDERSON, David, W. , GUO, Xiaojia , BAUMGARTNER, Jason, C. , PADIGARU, Muralidhara , PEYMAN, John, A. , SMITHSON, Glennda , CASMAN, Stacie J. , VOSS, Edward Z. , BOLDOG, Ferenc L. , PENA, Carol E.A. , CHAPOVAL, Andrei , RASTELLI, Luca , KEKUDA, Ramesh , VERNET, Corine A.M.
IPC分类号： A61K31/00
摘要： The present invention relates to novel polypeptides, and the nucleic acids encoding them, having properties related to stimulation of biochemical or physiological responses in a cell, a tissue, an organ or an organism. More particularly, the novel polypeptides are gene products of novel genes, or are specified biologically active fragments or derivatives thereof. Methods of use encompass diagnostic and prognostic assay procedures as well as methods of treating diverse pathological conditions.
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公开(公告)号：EP1409681A2
公开(公告)日：2004-04-21
申请号：EP02784815.9
申请日：2002-01-31
申请人： Curagen Corporation
发明人： TCHERNEV, Velizar, T. , SPYTEK, Kimberly, A. , ZERHUSEN, Bryan, D. , PATTURAJAN, Meera , SHIMKETS, Richard, A. , LI, Li , GANGOLLI, Esha, A. , PADIGARU, Muralidhara , ANDERSON, David, W. , RASTELLI, Luca , MILLER, Charles, E. , GERLACH, Valerie, L. , TAUPIER, Raymond, J., Jr. , GUSEV, Vladimir, Y. , COLMAN, Steven, D. , WOLENC, Adam, R.c/o CuraGen Corporation , PENA, Carol, E., A.c/o CuraGen Corporation , FURTAK, Katarzyna , GROSSE, William, M. , ALSOBROOK, John, P., II , LEPLEY, Denise, M. , RIEGER, Daniel, K. , BURGESS, Catherine, E.
IPC分类号： C12N15/12 , C12N1/21 , C07K14/47 , C07K14/705 , C07K16/18
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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3.发明公开
公开(公告)号：EP1513864A2
公开(公告)日：2005-03-16
申请号：EP03710863.6
申请日：2003-02-03
申请人： Curagen Corporation
发明人： ANDERSON, David, W. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , GORMAN, Linda , JI, Weizhen , KEKUDA, Ramesh , LI, Li , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr.
IPC分类号： C07K1/00 , C07K14/00 , C07K16/00 , C07K17/00 , G01N33/53 , C12P21/06 , C12N15/00 , C12N15/09 , C12N15/63
CPC分类号： C07K14/47
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
摘要翻译： 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及免疫特异性结合多肽的抗体，以及对多肽特异的新多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。
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公开(公告)号：EP1409679A2
公开(公告)日：2004-04-21
申请号：EP02715003.6
申请日：2002-02-26
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , ANDERSON, David, W. , BALLINGER, Robert A. , BOLDOG, Ferenc, L. , BURGESS, Catherine, E. , CASMAN, Stacie, J. , ELLERMAN, Karen, E. , GANGOLLI, Esha, A. , GERLACH, Valerie, L. , GILBERT, Jennifer, A. , GORMAN, Linda , GUO, Xiaojia , GUSEV, Vladimir, Y. , KEKUDA, Ramesh , LI, Li , LIU, Xiaohong , MALYANKAR, Uriel, M. , MILLER, Charles, E. , MILLET, Isabelle , PADIGARU, Muralidhara , PATTURAJAN, Meera , PENA, Carol, E., A. , PEYMAN, John, A. , RASTELLI, Luca , SHENOY, Suresh, G. , SHIMKETS, Richard, A. , SMITHSON, Glennda , SPYTEK, Kimberly, A. , STONE, David, J. , TAUPIER, Raymond, J., Jr. , TCHERNEV, Velizar, T. , VERNET, Corine, A., M. , ZERHUSEN, Bryan, D.
IPC分类号： C12N15/12 , C07K14/47 , C07K16/18 , C12Q1/68 , A61K38/17 , A61P3/00 , A61P21/00 , A61P3/10 , A61K39/395 , G01N33/68
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：EP1360291A2
公开(公告)日：2003-11-12
申请号：EP01973124.9
申请日：2001-09-17
申请人： Curagen Corporation
发明人： MISHRA, Vishnu, S. , SPYTEK, Kimberly, Ann , TAUPIER, Raymond, J., Jr. , VERNET, Corine, A., M. , COLMAN, Steven, D. , GORMAN, Linda , TCHERNEV, Velizar, T. , MALYANKAR, Uriel, M. , SHENOY, Suresh , TCHERNEV, Velizar, T. , PADIGARU, Muralidhara , SMITHSON, Glennda , MILLET, Isabelle , PEYMAN, John, A. , STONE, David , GUNTHER, Erik , ELLERMAN, Karen , GERLACH, Valerie L. , LI, Li , ZERHUSEN, Bryan D. , MACDOUGAL, John R. , RASTELLI, Luca
IPC分类号： C12N15/12
CPC分类号： A61B10/0275 , A61B2010/0208 , A61B2017/00398 , C07K14/475 , C07K14/5425 , C07K14/705 , C07K14/70571
摘要： Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatibility complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：EP1309683A2
公开(公告)日：2003-05-14
申请号：EP01928927.1
申请日：2001-04-26
申请人： Curagen Corporation
发明人： VERNET, Corine, A., M. , FERNANDES, Elma, R. , GERLACH, Valerie , SHIMKETS, Richard, A. , MALYANKAR, Uriel, M. , BOLDOG, Ferenc, L. , ZERHUSEN, Bryan, D. , SPYTEK, Kimberly, A. , MAJUMDER, Kumud , TCHERNEV, Velizar, T. , PADIGARU, Muralidhara , PATTURAJAN, Meera , BURGESS, Catherine, E. , GANGOLLI, Esha, A. , SMITHSON, Glennda , RASTELLI, Luca , MACDOUGALL, John, R. , TAUPIER, Raymond, J., Jr. , GROSSE, William, M. , ALSOBROOK, John, P., II
IPC分类号： C12N15/12 , C12N5/10 , C07K16/28 , C07K16/40 , C07K16/18 , C07K14/47 , C07K14/475 , C07K14/705 , C12N9/64 , G01N33/53 , C12Q1/68 , G01N33/50 , A61K48/00 , A61K38/16 , A61K39/00
CPC分类号： C12N9/6445 , A61K38/00 , A61K38/1725 , A61K38/177 , A61K38/18 , A61K38/2292 , A61K38/45 , A61K38/482 , A61K38/4886 , C07K14/47 , C07K14/475 , C07K14/705 , C12N9/6421 , C12N9/6424 , G01N33/5023 , G01N33/566 , G01N2500/04 , A61K2300/00
摘要： Disclosed herein are nucleic acid sequences that encode novel molecules (MOL) polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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7.发明公开
公开(公告)号：EP1432726A2
公开(公告)日：2004-06-30
申请号：EP02770481.6
申请日：2002-09-09
申请人： Curagen Corporation
发明人： ALSOBROOK, John, P., II , BURGESS, Catherine, E. , EDINGER, Shlomit, R. , GERLACH, Valerie, L. , LEPLEY, Denise, M. , PATTURAJAN, Meera , PENA, Carol, E., A. , RIEGER, Daniel, K. , SHIMKETS, Richard, A. , SPYTEK, Kimberly, A. , TAUPIER, Raymond, J., Jr. , ZHONG, Mei
IPC分类号： C07K1/00
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K48/00 , C07K2319/00
摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
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公开(公告)号：EP1255835A2
公开(公告)日：2002-11-13
申请号：EP01912743.0
申请日：2001-02-15
申请人： Curagen Corporation
发明人： VERNET, Corine, A., M. , SHIMKETS, Richard, A. , RASTELLI, Luca , BURGESS, Catherine, E. , TAUPIER, Raymond, J., Jr.
IPC分类号： C12N15/12 , C12N15/54 , C07K14/47 , C07K14/705 , C12N9/10 , C12N15/70 , C12N1/21 , C07K16/18 , C07K16/42 , C12Q1/68 , G01N33/577 , G01N33/68 , A61K38/00
CPC分类号： C07K14/47 , A61K38/00 , C12N9/1051
摘要： The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide, or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide, and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
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公开(公告)号：EP1255833A2
公开(公告)日：2002-11-13
申请号：EP01910722.6
申请日：2001-02-15
申请人： Curagen Corporation
发明人： MALYANKAR, Uriel, M. , TCHERNEV, Velizar T. , PADIGARU, Muralidhara , TAUPIER, Raymond, J., Jr. , SPYTEK, Kimberly, Ann , MAJUMDER, Kumud , GUO, Xiaojia , SPADERNA, Steven, K. , BOLDOG, Ferenc, L.
IPC分类号： C12N15/12 , C12N15/57 , C07K14/47 , C07K14/555 , C07K14/705 , C12N9/64 , C12Q1/68 , A61K38/17 , A61K38/48 , A61K48/00 , G01N33/53 , G01N33/68
CPC分类号： C07K14/47
摘要： The present invention provides isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
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公开(公告)号：EP1232266A2
公开(公告)日：2002-08-21
申请号：EP01918899.4
申请日：2001-03-20
申请人： Curagen Corporation
发明人： TAUPIER, Raymond, J., Jr. , MAJUMDER, Kumud , SPADERNA, Steven, K. , SMITHSON, Glenda , MEZES, Peter, S. , VERNET, Corine, A., M.
CPC分类号： C07K14/47
摘要： The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
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