公开(公告)号：EP1255833A2

公开(公告)日：2002-11-13

申请号：EP01910722.6

申请日：2001-02-15

申请人： Curagen Corporation

发明人： MALYANKAR, Uriel, M. ,  TCHERNEV, Velizar T. ,  PADIGARU, Muralidhara ,  TAUPIER, Raymond, J., Jr. ,  SPYTEK, Kimberly, Ann ,  MAJUMDER, Kumud ,  GUO, Xiaojia ,  SPADERNA, Steven, K. ,  BOLDOG, Ferenc, L.

IPC分类号： C12N15/12 ,  C12N15/57 ,  C07K14/47 ,  C07K14/555 ,  C07K14/705 ,  C12N9/64 ,  C12Q1/68 ,  A61K38/17 ,  A61K38/48 ,  A61K48/00 ,  G01N33/53 ,  G01N33/68

CPC分类号： C07K14/47

摘要： The present invention provides isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.

公开(公告)号：EP1360291A2

公开(公告)日：2003-11-12

申请号：EP01973124.9

申请日：2001-09-17

申请人： Curagen Corporation

发明人： MISHRA, Vishnu, S. ,  SPYTEK, Kimberly, Ann ,  TAUPIER, Raymond, J., Jr. ,  VERNET, Corine, A., M. ,  COLMAN, Steven, D. ,  GORMAN, Linda ,  TCHERNEV, Velizar, T. ,  MALYANKAR, Uriel, M. ,  SHENOY, Suresh ,  TCHERNEV, Velizar, T. ,  PADIGARU, Muralidhara ,  SMITHSON, Glennda ,  MILLET, Isabelle ,  PEYMAN, John, A. ,  STONE, David ,  GUNTHER, Erik ,  ELLERMAN, Karen ,  GERLACH, Valerie L. ,  LI, Li ,  ZERHUSEN, Bryan D. ,  MACDOUGAL, John R. ,  RASTELLI, Luca

IPC分类号： C12N15/12

CPC分类号： A61B10/0275 ,  A61B2010/0208 ,  A61B2017/00398 ,  C07K14/475 ,  C07K14/5425 ,  C07K14/705 ,  C07K14/70571

摘要： Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatibility complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

公开(公告)号：EP1349930A2

公开(公告)日：2003-10-08

申请号：EP01977537.8

申请日：2001-10-05

申请人： Curagen Corporation

发明人： SHIMKETS, Richard, A. ,  TAUPIER, Raymond, J., Jr. ,  BURGESS, Catherine, E. ,  ZERHUSEN, Bryan, D. ,  MEZES, Peter, S. ,  RASTELLI, Luca ,  MALYANKAR, Uriel, M. ,  GROSSE, William, M. ,  ALSOBROOK, John, P., II ,  LEPLEY, Denise, M. ,  SPYTEK, Kimberly, Ann ,  LI, Li ,  EDINGER, Shlomit ,  GERLACH, Valerie ,  ELLERMAN, Karen ,  MACDOUGALL, John ,  GUNTHER, Erik ,  MILLET, Isabelle ,  STONE, David ,  SMITHSON, Glennda ,  SZEKERES, Edward S., Jr.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/475 ,  C07K14/705 ,  C12N15/63 ,  C12N1/21 ,  C12N5/10 ,  C12Q1/68 ,  G01N33/68

CPC分类号： C12Q1/6883 ,  A01K2217/05 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/47 ,  C12Q2600/156 ,  C12Q2600/158

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

公开(公告)号：EP1268540A2

公开(公告)日：2003-01-02

申请号：EP01923104.2

申请日：2001-04-03

申请人： Curagen Corporation

发明人： VERNET, Corine, A., M. ,  BURGESS, Catherine, E. ,  FERNANDES, Elma ,  TAUPIER, Raymond, J., Jr. ,  QUINN, Kerry, E. ,  SPYTEK, Kimberly, Ann ,  RASTELLI, Luca ,  HERRMANN, John, L.

IPC分类号： C07K14/47 ,  C07K14/705 ,  C07K14/745 ,  C07K14/485 ,  C07K14/54 ,  C07K14/475 ,  C07K14/51 ,  C12N15/12 ,  C12N5/10 ,  C07K16/18 ,  G01N33/68 ,  C12Q1/68 ,  G01N33/50 ,  A61K38/16

摘要： Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.