公开(公告)号：EP1383893A2

公开(公告)日：2004-01-28

申请号：EP02707409.5

申请日：2002-01-07

申请人： Curagen Corporation

发明人： KEKUDA, Ramesh ,  ALSOBROOK, John, P., II ,  TCHERNEV, Velizar, T. ,  LIU, Xiaohong ,  SPYTEK, Kimberly, A. ,  PATTURAJAN, Meera ,  GROSSE, William M. ,  LEPLEY, Denise, M. ,  BURGESS, Catherine, E. ,  VERNET, Corine, A., M. ,  LI, Li ,  GORMAN, Linda ,  EDINGER, Schlomit ,  SCIORE, Paul ,  ELLERMAN, Karen ,  MALYANKAR, Uriel ,  ROTHENBERG, Mark ,  STONE, David ,  BOLDOG, Ferenc ,  GUO, Xiaojia ,  SHENOY, Suresh ,  ANDERSON, David ,  PADIGARU, Muralidhara ,  TAUPIER, Raymond, J. ,  MILLER, Charles, E. ,  EISEN, Andrew

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/18 ,  G01N33/53 ,  C12Q1/68 ,  G01N33/68 ,  G01N33/50 ,  A61K38/17 ,  A61K48/00 ,  A61K39/395

CPC分类号： C07K14/475 ,  A61K38/00 ,  A61K2039/505 ,  A61K2039/53 ,  C07K14/47 ,  C07K14/57581 ,  C07K14/65 ,  C07K14/705 ,  C07K14/7055 ,  C12N9/22 ,  C12Q1/6883 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N2333/47 ,  G01N2333/475 ,  G01N2333/5759 ,  G01N2333/65 ,  G01N2333/705 ,  G01N2333/7055

摘要： Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these human nucleic acids and proteins.

公开(公告)号：EP1407018A2

公开(公告)日：2004-04-14

申请号：EP01993355.5

申请日：2001-10-26

申请人： Curagen Corporation

发明人： GANGOLLI, Esha, A. ,  SPYTEK, Kimberly, A. ,  GILBERT, Jennifer ,  CASMAN, Stacie ,  BLALOCK, Angela ,  LI, Li ,  VERNET, Corine, A., M. ,  SHENOY, Suresh ,  MISHRA, Vishnu ,  FURTAK, Katarzyna ,  GERLACH, Valerie ,  EDINGER, Shlomit ,  MALYANKAR, Uriel ,  STONE, David ,  MILLET, Isabelle ,  SMITHSON, Glennda ,  GUNTHER, Erik ,  PADIGARU, Muralidhara ,  TAUPIER, Raymond, J., Jr. ,  ANDERSON, David ,  ELLERMAN, Karen

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/18 ,  G01N33/53 ,  C12Q1/68 ,  G01N33/50 ,  A61K39/395 ,  A61K31/7088 ,  A61K38/17

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K39/00

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

公开(公告)号：EP1349930A2

公开(公告)日：2003-10-08

申请号：EP01977537.8

申请日：2001-10-05

申请人： Curagen Corporation

发明人： SHIMKETS, Richard, A. ,  TAUPIER, Raymond, J., Jr. ,  BURGESS, Catherine, E. ,  ZERHUSEN, Bryan, D. ,  MEZES, Peter, S. ,  RASTELLI, Luca ,  MALYANKAR, Uriel, M. ,  GROSSE, William, M. ,  ALSOBROOK, John, P., II ,  LEPLEY, Denise, M. ,  SPYTEK, Kimberly, Ann ,  LI, Li ,  EDINGER, Shlomit ,  GERLACH, Valerie ,  ELLERMAN, Karen ,  MACDOUGALL, John ,  GUNTHER, Erik ,  MILLET, Isabelle ,  STONE, David ,  SMITHSON, Glennda ,  SZEKERES, Edward S., Jr.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/475 ,  C07K14/705 ,  C12N15/63 ,  C12N1/21 ,  C12N5/10 ,  C12Q1/68 ,  G01N33/68

CPC分类号： C12Q1/6883 ,  A01K2217/05 ,  A61K38/00 ,  A61K39/00 ,  A61K48/00 ,  C07K14/47 ,  C12Q2600/156 ,  C12Q2600/158

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

公开(公告)号：EP1399552A2

公开(公告)日：2004-03-24

申请号：EP01952843.9

申请日：2001-07-18

申请人： Curagen Corporation

发明人： ZERHUSEN, Bryan ,  PADIGARU, Muralidhara ,  LI, Li ,  BURGESS, Catherine, E. ,  CASMAN, Stacie, J. ,  SPYTEK, Kimberly, A. ,  MISHRA, Vishnu ,  TAYLOR, Sarah ,  SHENOY, Suresh ,  VERNET, Corine ,  GERLACH, Valerie ,  ELLERMAN, Karen ,  MACDOUGALL, John, R. ,  STONE, David ,  SMITHSON, Glennda ,  GROSSE, William, M. ,  ALSOBROOK, John, P., II ,  LEPLEY, Denise, M. ,  TCHERNEV, Velizar, T. ,  TAILLON, Bruce

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K16/28 ,  G01N33/53 ,  C12Q1/68

摘要： Disclosed herein are nucleic acid sequences that encode G-proteincoupled-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospeficically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human acids and proteins.

公开(公告)号：EP1373313A2

公开(公告)日：2004-01-02

申请号：EP01979901.4

申请日：2001-09-27

申请人： Curagen Corporation

发明人： GERLACH, Valerie, L. ,  MACDOUGALL, John, R. ,  SMITHSON, Glennda ,  MILLET, Isabelle ,  STONE, David ,  GUNTHER, Erik ,  ELLERMAN, Karen ,  GROSSE, William, M. ,  ALSOBROOK, John, P., II ,  LEPLEY, Denise, M. ,  BURGESS, Catherine, E. ,  PADIGARU, Muralidhara ,  KEKUDA, Ramesha ,  SPYTEK, Kimberly, A. ,  LEACH, Martin, D. ,  SHIMKETS, Richard, A.

IPC分类号： C07K14/47 ,  C12N15/12 ,  C12N5/10 ,  C07K16/18 ,  G01N33/53 ,  G01N33/566 ,  C12Q1/68 ,  A61K38/17 ,  A61K39/395 ,  A61K31/713 ,  A61P9/10 ,  A61P3/10

CPC分类号： C07K14/47 ,  A61K38/00

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antiboides, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

摘要翻译： 本文公开了编码新多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗生素以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。

公开(公告)号：EP1360291A2

公开(公告)日：2003-11-12

申请号：EP01973124.9

申请日：2001-09-17

申请人： Curagen Corporation

发明人： MISHRA, Vishnu, S. ,  SPYTEK, Kimberly, Ann ,  TAUPIER, Raymond, J., Jr. ,  VERNET, Corine, A., M. ,  COLMAN, Steven, D. ,  GORMAN, Linda ,  TCHERNEV, Velizar, T. ,  MALYANKAR, Uriel, M. ,  SHENOY, Suresh ,  TCHERNEV, Velizar, T. ,  PADIGARU, Muralidhara ,  SMITHSON, Glennda ,  MILLET, Isabelle ,  PEYMAN, John, A. ,  STONE, David ,  GUNTHER, Erik ,  ELLERMAN, Karen ,  GERLACH, Valerie L. ,  LI, Li ,  ZERHUSEN, Bryan D. ,  MACDOUGAL, John R. ,  RASTELLI, Luca

IPC分类号： C12N15/12

CPC分类号： A61B10/0275 ,  A61B2010/0208 ,  A61B2017/00398 ,  C07K14/475 ,  C07K14/5425 ,  C07K14/705 ,  C07K14/70571

摘要： Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatibility complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.