摘要:
The instant invention provides the porcine GRF receptor protein. The invention also provides DNA compounds encoding the pGRF receptor, recombinant DNA cloning and expression vectors comprising said DNA sequence, and recombinant host cells comprising said vectors. The invention also provides methods of making the pGRF receptor in recombinant and solid phase systems. The invention also provides methods of using the pGRF receptor in assay systems. The invention also provides methods of using said DNA sequences as probes to isolate and characterize GRF receptors and corresponding DNA sequences from other species.
摘要:
The present invention relates to novel selectable and autonomously replicating recombinant DNA expression vectors which code for bovine growth hormone derivatives. The invention further comprises novel transformants of the aforementioned vectors, a method of making proteinaceous granules and a method of use.
摘要:
A process for selectively removing a β-cyanoethyl blocking group from the phosphate moiety of a nucleotide or polynucleotide, which comprises treating said nucleotide or polynucleotide with a primary amine having from 3 to 5 carbon atoms or diethylamine.
摘要:
This invention is in the general field of molecular biology as applied to pharmaceutical or animal health research and development. The invention includes proteins, DNA compounds, vectors, and methods useful for expressing proteins that are regulate the body's volume of adipose tissue.
摘要:
The present invention concerns novel DNA compounds which function as transcriptional activating sequences. Recombinant DNA expression vectors which contain the transcriptional activating sequences and host cells transformed with these expression vectors are also provided. When properly positioned in an expression vector, the novel transcriptional activating sequences enable regulatable expression of an operably linked gene and enhance the structural stability of the expression vector.
摘要:
The present invention provides polypeptide compounds which are two forms of the porcine growth hormone releasing factor (pGRF) precursor and the pGRF leader peptide, and a new form of mature pGRF. The invention also provides DNA compounds encoding these polypeptide compounds and mature pGRF, pharmaceutical compositions and methods for the inducement of growth hormone release.
摘要:
The present invention provides novel analogs of growth hormone releasing factor (GRF). Chemically modified versions of these molecules are also provided as are DNA compounds encoding GRF analogs. Some of the polypeptide compounds can be obtained in large yields by production of the compounds in E . coli . The invention also provides pharmaceutical compositions and methods for the inducement of growth hormone release.
摘要:
The present invention provides polypeptide compounds which are two forms of the bovine growth hormone releasing factor (bGRF) precursor and the bGRF leader peptide, and a new form of mature bGRF. The invention also provides DNA compounds encoding these polypeptide compounds and mature bGRF, pharmaceutical compositions and methods for the inducement of growth hormone release.