利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

11 条记录 (耗时 0.017 秒)

    Photometric in plane detection using a rotatable disc
    1.
    发明公开
    Photometric in plane detection using a rotatable disc 审中-公开
    在eeene einer drebbaren Scheibe的Photometrische detektion

    公开(公告)号：EP1752758A1

    公开(公告)日：2007-02-14

    申请号：EP05017277.4

    申请日：2005-08-09

    申请人： Roche Diagnostics GmbH ,  F. HOFFMANN-LA ROCHE AG

    发明人： Griss, Patrick ,  Hein, Heinz-Michael ,  Jaeggi, Rainer ,  Savatic, Goran

    IPC分类号： G01N21/07

    CPC分类号： G01N21/0303 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0806 ,  B01L2300/168 ,  G01N35/00069

    摘要： On an analytical device for photometric detection of chemistry and/or fluid samples comprising a rotatable disc like body (1) a plurality of receptables (7) for fluid samples and optical means (9) for guiding light beams through the receptables are arranged. At least part of the optical means (9) are designed and/or arranged such, that at least part of the light beams is deflected and guided through the receptables in an angle to the radially outward direction on the disc like body (1) which means in an angle to the radius, connecting the respective optical means with the rotation axis (9) of the disc like body (1). (fig.1)

    摘要翻译： 在用于测量化学和/或流体样品的用于光学测量的分析装置中，包括可旋转盘状体（1），用于流体样品的多个容器（7）和用于引导光束穿过容器的光学装置（9）。 光学装置（9）的至少一部分被设计和/或布置成使得至少部分光束被偏转并且引导穿过接收器与盘状体（1）上的径向向外的方向成一角度 意指与半径成一定角度，将相应的光学装置与盘状体（1）的旋转轴线（9）相连接。 （图。1）

    Systems and method for manipulating liquid fluids in microfluidic devices
    3.
    发明公开
    Systems and method for manipulating liquid fluids in microfluidic devices 审中-公开
    系统与Verfahren zum ManipulierenflüssigerFluide in mikrofluidischen Vorrichtungen

    公开(公告)号：EP2332653A1

    公开(公告)日：2011-06-15

    申请号：EP09179110.3

    申请日：2009-12-14

    申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

    发明人： Korner, Stephan ,  Oosterbroek, Edwin ,  Jaeggi, Rainer ,  Siljegovic, Vuk

    IPC分类号： B01L3/00

    CPC分类号： B01L3/50273 ,  B01L2300/0861 ,  B01L2300/1844 ,  B01L2300/1855 ,  B01L2400/0409 ,  B01L2400/0463 ,  B01L2400/0487

    摘要： The present invention pertains to various systems for manipulating liquid fluids. A first system includes a microfluidic device (102) provided with at least one microfluidic structure communicating with at least one port (104) for introducing said liquid fluid into said microfluidic structure, and at least one nozzle (108) adapted for ejecting an air stream (109), said nozzle being operatively coupled to said port so that said ejected air stream is either made to flow across said port to generate said negative pressure in said microfluidic structure or is made to at least partially flow into said port to generate said positive pressure therein. Alternatively, a substrate may face the device which can be spun around a spin axis and is being provided with one or more step-like protrusions for generating a positive and/or negative pressure. Yet alternatively, a support for supporting the device which can be spun around a spin axis can be envisaged. The support is being provided with at least one duct for generating a positive and/or negative pressure in the microfluidic structure. Yet alternatively, an open-top chamber adapted to be covered by the microfluidic device including at least one cavity communicating with the port and being connected to a pump can be envisaged. The invention further pertains to a method for manipulating liquid fluids in a microfluidic structure, comprising the following steps of: introducing said liquid fluid through one first port into said structure; making air to either flow across said first port or a second port being different from the first port and communicating with the microfluidic structure to generate a negative pressure in said structure and/or to at least partially flow into said port to generate a positive pressure in said structure; and spinning said microfluidic structure around a spin axis to generate a centrifugal force acting on said liquid fluid contained in said microfluidic structure.

    摘要翻译： 本发明涉及用于操纵液体流体的各种系统。 第一系统包括设置有至少一个微流体结构的微流体装置（102），该至少一个微流体结构与至少一个用于将所述液体流体引入所述微流体结构的端口（104）连通，以及至少一个喷嘴（108） （109），所述喷嘴可操作地联接到所述端口，使得所述喷射的空气流被制成流过所述端口以在所述微流体结构中产生所述负压，或者使其至少部分地流入所述端口以产生所述正 压力。 或者，衬底可以面对能够围绕旋转轴旋转的装置，并且设置有一个或多个用于产生正和/或负压力的阶梯状突起。 或者，可以设想用于支撑可围绕旋转轴旋转的装置的支撑件。 该支撑件设置有至少一个用于在微流体结构中产生正和/或负压力的管道。 或者，可以设想适于被微流体装置覆盖的敞开顶部室，其包括与端口连通并连接到泵的至少一个空腔。 本发明还涉及一种用于操纵微流体结构中的液体流体的方法，包括以下步骤：将所述液体流体通过一个第一端口引入所述结构体; 使空气流过所述第一端口或与第一端口不同的第二端口并与微流体结构连通以在所述结构中产生负压并且/或至少部分地流入所述端口以产生正压力 说结构 以及围绕旋转轴线旋转所述微流体结构以产生作用在所述微流体结构中包含的所述液体流体上的离心力。

    SYSTEM FOR THE ANALYSIS OF LIQUID SAMPLES
    4.
    发明公开
    SYSTEM FOR THE ANALYSIS OF LIQUID SAMPLES 审中-公开
    系统ZUR ANALYZE VONFLÜSSIGPROBEN

    公开(公告)号：EP2952906A1

    公开(公告)日：2015-12-09

    申请号：EP09167520.7

    申请日：2009-08-07

    申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

    发明人： Jaeggi, Rainer ,  Gutmann, Oliver ,  Oosterbroek, Edwin ,  Glauser, Michael ,  Heinrich, Michael ,  Hein, Heinz-Michael

    IPC分类号： G01N35/08 ,  G01N35/10

    CPC分类号： G01N35/1095 ,  B01L2200/027 ,  G01N35/085 ,  G01N2035/00158 ,  G01N2035/1034

    摘要： The present invention relates to a system (1) for the automated analysis of liquid samples, comprising: one or more processing units (3) for reaction between said samples and one or more reagents to take place to thereby obtain reaction products; a sample unit (7) for supplying said samples to said one or more processing units (3); a reagent unit (5) equipped with plural reagent vessels (8) containing one or more reagents for mixing with said samples; a distribution unit (6) for distributing fluids including said one or more reagents provided with plural distribution lines (13) at least some of which being connected to said reagent vessels (8) and said one or more processing units (3); at least one analytical unit (2) for analyzing said samples based on said reaction products, said analytical unit (2) including at least one detector (4, 19) for detecting said reaction products.

    摘要翻译： 本发明涉及一种用于液体样品的自动分析的系统（1），包括：一个或多个处理单元（3），用于在所述样品和一种或多种试剂之间进行反应，从而获得反应产物; 用于将所述样本提供给所述一个或多个处理单元（3）的采样单元（7）; 配备有多个试剂容器（8）的试剂单元（5），其包含一种或多种用于与所述样品混合的试剂; 分配单元（6），用于分配包含所述一种或多种试剂的流体，所述试剂具有多个分配管线（13），其中至少一些连接到所述试剂容器（8）和所述一个或多个处理单元（3）; 至少一个用于基于所述反应产物分析所述样品的分析单元（2），所述分析单元（2）包括用于检测所述反应产物的至少一个检测器（4,19）。

    Body fluid sampling device
    5.
    发明公开
    Body fluid sampling device 有权
    体液采样装置

    公开(公告)号：EP2705792A1

    公开(公告)日：2014-03-12

    申请号：EP13183580.3

    申请日：2005-03-04

    申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

    发明人： Calasso, Irio Giuseppe ,  Griss, Patrick ,  Jaeggi, Rainer ,  Sarofim, Emad

    IPC分类号： A61B5/15 ,  A61B5/145 ,  A61B5/1486

    CPC分类号： A61B5/14532 ,  A61B5/1411 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150251 ,  A61B5/150297 ,  A61B5/150358 ,  A61B5/150419 ,  A61B5/150435 ,  A61B5/150503 ,  A61B5/15107 ,  A61B5/15117

    摘要： Body fluid sampling device comprising a skin-piercing element (10) having a fluid pathway (11) for receiving body fluid, at least a portion of said fluid pathway is open to the environment and further comprising a fluid receiving means (40) being spaced from said fluid pathway so that fluid in said pathway will not contact the fluid receiving means initially. Said fluid receiving means may have a test zone (45) for performing an analytical reaction. Fluid from said channel is contacted with said fluid receiving means either by bringing the fluid receiving means and the fluid into mechanical contact or by electrically transporting fluid from the channel onto the fluid receiving means.

    摘要翻译： 包括具有用于接收体液的流体通路（11）的皮肤穿刺元件（10）的体液采集装置，所述流体通路的至少一部分对环境开放，并且还包括流体接收装置（40） 从所述流体通路流出，使得所述通路中的流体最初不会与流体接收装置接触。 所述流体接收装置可具有用于执行分析反应的测试区（45）。 来自所述通道的流体通过使流体接收装置和流体进入机械接触或通过将流体从通道电力传输到流体接收装置上而与所述流体接收装置接触。

    Plasma separation on a disk like device
    6.
    发明公开
    Plasma separation on a disk like device 审中-公开
    Plasmatrennung auf einerplattenähnlichenVorrichtung

    公开(公告)号：EP1795894A1

    公开(公告)日：2007-06-13

    申请号：EP05026571.9

    申请日：2005-12-06

    申请人： Roche Diagnostics GmbH ,  F.HOFFMANN-LA ROCHE AG

    发明人： Jaeggi, Rainer ,  Griss, Patrick ,  Wahl, Hans-Peter

    IPC分类号： G01N33/49

    CPC分类号： G01N21/07 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2400/0409 ,  B01L2400/086 ,  G01N33/491

    摘要： Device for at least partial fractioning or separating fluid from higher density and/or solid particles containing samples, the device comprising a movable or drivable body as e.g. a rotatable plate-like or disc-like body (1) with at least one flow path (3). Within this flow path at one internal wall surface at moving or driving the body the flow velocity of the fluid sample is higher compared with the velocity at e.g. the opposite internal wall surface. At least the one path (3) is comprising at the mentioned one internal wall surface (4) means (5) to at least delay the flow of the fluid sample mixture along the mentioned wall surface. The device is e.g. suitable for the separation of blood e.g. of plasma from at least red blood cells, preferably from red and white blood cells to achieve blood plasma with high purity for analytical reasons.

    摘要翻译： 用于至少部分分馏或从含有较高密度和/或固体颗粒的样品中分离流体的装置，该装置包括可移动或可驱动的主体， 具有至少一个流动路径（3）的可旋转板状或圆盘状体（1）。 在移动或驱动身体的一个内壁表面的该流动路径内，流体样品的流速比例如流体样品的流速高。 相对的内壁表面。 至少一个路径（3）包括在所述的一个内壁表面（4）装置（5），以至少延迟流体样品混合物沿所述壁表面的流动。 该装置是例如 适合分离血液 的血浆从至少红细胞，优选从红细胞和白细胞获得，以获得高纯度的血浆，用于分析的原因。