公开(公告)号：EP1356032A2

公开(公告)日：2003-10-29

申请号：EP01955908.7

申请日：2001-07-20

申请人： Incyte Genomics, Inc. ,  Thornton, Michael

发明人： YUE, Henry ,  KHAN, Farrah, A. ,  GURURAJAN, Rajagopal ,  HAFALIA, April, J., A. ,  CHAWLA, Narinder K. ,  ARVIZU, Chandra S. ,  RAMKUMAR, Jayalaxmi ,  GANDHI, Ameena, R. ,  POLICKY, Jennifer, L. ,  BAUGHN, Mariah, R. ,  TRIBOULEY, Catherine, M. ,  BANDMAN, Olga ,  NGUYEN, Danniel, B. ,  LU, Yan ,  BURFORD, Neil ,  LAL, Preeti ,  DING, Li ,  YAO, Monique, G. ,  ELLIOTT, Vicki, S. ,  RECIPON, Shirley, A. ,  KEARNEY, Liam ,  LU, Dyung, Aina, M. ,  GREENWALD, Sara, R. ,  TANG, Y., Tom ,  XU, Yuming ,  WALSH, Roderick, T. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  JACKSON, Jennifer, L. ,  THORNTON, Michael

IPC分类号： C12N15/00 ,  C12N15/54 ,  C07K16/40 ,  C12N15/63 ,  C12N9/12 ,  A61K38/45 ,  C12Q1/48 ,  C12Q1/68

CPC分类号： C12N9/1205

摘要： The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associatedd withd abberant expression of PKIN.

摘要翻译： 本发明提供了鉴定和编码PKIN的人类人类激酶（PKIN）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PKIN异常表达相关的疾病的方法。

公开(公告)号：EP1320548A2

公开(公告)日：2003-06-25

申请号：EP01939490.7

申请日：2001-05-25

申请人： Incyte Genomics, Inc.

发明人： THORNTON, Michael ,  CHAWLA, Narinder, K ,  YUE, Henry ,  NGUYEN, Danniel, B ,  LAI, Preeti ,  GANDHI, Ameena, R ,  TRIBOULEY, Catherine, M ,  YAO, Monique, G ,  RAMKUMAR, Jayalaxmi ,  AU-YOUNG, Janice ,  LU, Yan ,  TANG, Y., Tom ,  AZIMZAI, Yalda ,  BRUNS, Christopher M., ,  GRIFFIN, Jennifer, A ,  YANG, Junming ,  SANJANWALA, Madhu, S ,  RAUMANN, Brigitte, E ,  LEE, Ernestine, A ,  HAFALIA, April ,  BAUGHN, Mariah, R ,  GREEN, Barrie, D ,  KHAN, Farrah, A ,  KEARNEY, Liam ,  ELLIOT, Vicki, S ,  SEILHAMER, Jeffrey, J ,  POLICKY, Jennifer, L ,  BOROWSKY, Mark, L ,  BURFORD, Neil ,  DING, Li ,  LU, Dyung, Aina, M ,  JACKSON, Jennifer, L

IPC分类号： C07K14/705

CPC分类号： C07K14/47

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

公开(公告)号：EP1313857A2

公开(公告)日：2003-05-28

申请号：EP01952492.5

申请日：2001-07-06

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  AZIMZAI, Yalda ,  DAS, Debopriya ,  THORNTON, Michael ,  LU, Dyung, Aina, M. ,  TRIBOULEY, Catherine, M. ,  YUE, Henry ,  GANDHI, Ameena, R. ,  WALIA, Narinder, K. ,  KHAN, Farrah, A. ,  LU, Yan ,  YAO, Monique, G. ,  HAFALIA, April, J., A. ,  ELLIOTT, Vicki, S. ,  PATTERSON, Chandra ,  LAL, Preeti ,  RAMKUMAR, Jayalaxmi ,  NGUYEN, Danniel, B. ,  BAUGN, Mariah, R.

IPC分类号： C12N15/53 ,  C12N15/55 ,  C12N9/16 ,  C12N9/20 ,  C12N9/02 ,  C12N15/63 ,  C12N1/21 ,  C12N5/10 ,  C12Q1/26 ,  C12Q1/34 ,  C12Q1/68 ,  C07K16/40 ,  G01N33/53 ,  G01N33/68 ,  A61K38/44

CPC分类号： C12N9/20 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4702

摘要： The invention provides human lipid metabolism molecules (LMM) and polynucleotides which identify and encode LMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LMM.

摘要翻译： 本发明提供了识别和编码LMM的人类脂质代谢分子（LMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与LMM异常表达相关的病症的方法。

公开(公告)号：EP1299546A2

公开(公告)日：2003-04-09

申请号：EP01950652.6

申请日：2001-06-29

申请人： Incyte Genomics, Inc.

发明人： LEE, Ernestine, A. ,  TANG, Y., Tom ,  LU, Dyung, Aina, M. ,  TRIBOULEY, Catherine, M. ,  GANDHI, Ameena, R. ,  LU, Yan ,  BAUGHN, Mariah, R. ,  WARREN, Bridget, A. ,  THORNTON, Michael ,  YUE, Henry ,  HILLMAN, Jennifer, L. ,  PATTERSON, Chandra ,  ELLIOTT, Vicki, S. ,  THANGAVELU, Kavitha ,  RAMKUMAR, Jayalaxmi ,  WALIA, Narinder, K. ,  YAO, Monique, G.

IPC分类号： C12N15/52 ,  C12N9/00 ,  C12N5/10 ,  C12Q1/25 ,  C12Q1/68 ,  C07K16/40 ,  A61K38/53 ,  A61K39/395 ,  A01K67/027

CPC分类号： C12N9/93 ,  A61K38/00

摘要： The invention provides human aminoacyl tRNA synthetases (ATRS) and polynucleotides which identify and encode ATRS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ATRS.

公开(公告)号：EP1297150A2

公开(公告)日：2003-04-02

申请号：EP01928748.1

申请日：2001-04-20

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  GANDHI, Ameena, R. ,  TRIBOULEY, Catherine, M. ,  KEARNEY, Liam ,  GRIFFIN, Jennifer, A. ,  NGUYEN, Danniel, B. ,  BANDMAN, Olga ,  LU, Dyung, Aina, M. ,  LAL, Preeti ,  BURFORD, Neil ,  KHAN, Farrah, A. ,  WALIA, Narinder, K. ,  YAO, Monique, G. ,  PATTERSON, Chandra ,  BURRILL, John, D. ,  MARCUS, Gregory, A. ,  ZINGLER, Kurt, A. ,  RECIPON, Shirley, A. ,  LU, Yan ,  POLICKY, Jennifer, L. ,  THORNTON, Michael ,  TANG, Y., Tom ,  HAFALIA, April ,  ELLIOTT, Vicki, S. ,  BAUGHN, Mariah, R. ,  WALSH, Roderick, T. ,  RAMKUMAR, Jayalaxmi ,  BOROWSKY, Mark, L. ,  AU-YOUNG, Janice ,  HILLMAN, Jennifer, L. ,  GURURAJAN, Rajagopal

IPC分类号： C12N15/54 ,  C12N9/12 ,  C12Q1/68 ,  A61K38/45 ,  A01K67/027 ,  G01N33/53 ,  G01N33/68

CPC分类号： C12N9/12 ,  A01K2217/05 ,  A61K38/00

摘要： The invention provides human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.

摘要翻译： 本发明提供了识别和编码PKIN的人类激酶（PKIN）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PKIN异常表达相关的病症的方法。

公开(公告)号：EP1297128A2

公开(公告)日：2003-04-02

申请号：EP01939176.2

申请日：2001-05-17

申请人： Incyte Genomics, Inc.

发明人： PATTERSON, Chandra ,  LU, Dyung, Aina, M. ,  THORNTON, Michael ,  LU, Yan ,  TRIBOULEY, Catherine, M. ,  GRAUL, Richard ,  KHAN, Farrah, A. ,  GANDHI, Ammeena, R. ,  WALIA, Narinder, K. ,  NGUYEN, Danniel, B. ,  YUE, Henry ,  HAFALIA, April ,  ELLIOTT, Vicki, S. ,  LAL, Preeti ,  REDDY, Roopa ,  KALLICK, Deborah, A. ,  TANG, Tom, Y. ,  AU-YOUNG, Janice

IPC分类号： C12N15/12 ,  C07K14/705 ,  C12N5/10 ,  C07K16/28 ,  C12Q1/68 ,  G01N33/50 ,  A61K9/00 ,  A61K39/395

CPC分类号： C07K14/705

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

公开(公告)号：EP1551872A2

公开(公告)日：2005-07-13

申请号：EP02746660.6

申请日：2002-06-20

申请人： Incyte Genomics, Inc.

发明人： BAUGHN, Mariah, R. ,  CHAWLA, Narinder, K. ,  RICHARDSON, Thomas, W. ,  ISON, Craig, H. ,  YANG, Junming ,  EMERLING, Brooke, M. ,  THORNTON, Michael ,  BOROWSKY, Mark, L. ,  RAMKUMAR, Jayalaxmi ,  YUE, Henry ,  GRAUL, Richard, C. ,  HAFALIA, April, J., A. ,  LU, Dyung Aina, M. ,  LU, Yan ,  KALLICK, Deborah, A. ,  GANDHI, Ameena, R. ,  WARREN, Bridget, A. ,  LEE, Ernestine, A. ,  SWARNAKAR, Anita ,  WALSH, Roderick, T. ,  YAO, Monique, G. ,  GRIFFIN, Jennifer, A. ,  AU-YOUNG, Janice, K. ,  KHAN, Farrah, A. ,  LEE, Soo, Yeun ,  ELLIOTT, Vicki, S.

IPC分类号： C07K14/705 ,  C12N15/12

CPC分类号： C07K14/705

摘要： Various embodiments of the invention provide human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码GCREC的人G蛋白偶联受体（GCREC）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与GCREC的异常表达相关的病症的方法。

公开(公告)号：EP1339854A2

公开(公告)日：2003-09-03

申请号：EP01966141.2

申请日：2001-08-22

申请人： Incyte Genomics, Inc.

发明人： GRIFFIN, Jennifer, A. ,  PATTERSON, Chandra ,  GANDHI, Ameena, R. ,  LU, Yan ,  YAO, Monique, G. ,  BAUGHN, Mariah, R. ,  CHAWLA, Narinder, K. ,  HAFALIA, April, J., A. ,  DING, Li ,  TRIBOULEY, Catherine, M. ,  DAS, Debopriya ,  THORNTON, Michael ,  LAL, Preeti

IPC分类号： C12N15/55 ,  C12N9/20 ,  C12N9/02 ,  C12N1/21 ,  C07K16/40 ,  C12Q1/34 ,  C12Q1/68 ,  A01K67/027 ,  A61K38/46 ,  A61K39/395

CPC分类号： C12N9/20 ,  A61K38/00

摘要： The invention provides human lipid metabolism enzymes (LMM) and polynucleotides which identify and encode LMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LMM.

摘要翻译： 本发明提供了鉴定和编码LMM的人脂质代谢酶（LMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与LMM异常表达相关的病症的方法。

公开(公告)号：EP1309700A2

公开(公告)日：2003-05-14

申请号：EP01948678.6

申请日：2001-06-21

申请人： Incyte Genomics, Inc.

发明人： THORNTON, Michael ,  DING, Li ,  PATTERSON, Chandra ,  YAO, Monique, G. ,  TRIBOULEY, Catherine, M. ,  LAL, Preeti ,  HAFALIA, April, J., A. ,  BAUGHN, Mariah, R. ,  RAMKUMAR, Jayalaxmi ,  LU, Yan ,  WALIA, Narinder, K.

IPC分类号： C12N15/55 ,  C12N9/16 ,  C12Q1/68 ,  C07K16/40 ,  G01N33/50 ,  G01N33/53 ,  A61K38/46

CPC分类号： C12N9/16 ,  A61K38/00

摘要： The invention provides human phosphodiesterases (HPDE) and polynucleotides which identify and encode HPDE. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of HPDE.

公开(公告)号：EP1303609A2

公开(公告)日：2003-04-23

申请号：EP01959203.9

申请日：2001-07-25

申请人： Incyte Genomics, Inc.

发明人： THORNTON, Michael ,  PATTERSON, Chandra ,  LAL, Preeti ,  BURFORD, Neil ,  YUE, Henry ,  GANDHI, Ameena, R. ,  ELLIOT, Vicki, S. ,  RAMKUMAR, Jayalaxmi ,  BAUGHN, Mariah, R. ,  KALLICK, Deborah, A. ,  WALIA, Narinder, K. ,  HAFALIA, April, J., A. ,  YAO, Monique, G. ,  LU, Yan ,  TRIBOULEY, Catherine, M. ,  POLICKY, Jennifer, L. ,  KEARNEY, Liam ,  GRAUL, Richard, C. ,  WARREN, Bridget, A. ,  LEE, Ernestine A. ,  DING, Li

IPC分类号： C12N15/12 ,  C07K14/705 ,  C07K16/28 ,  C12Q1/68 ,  G01N33/50 ,  G01N33/577 ,  A61K38/17 ,  A01K67/027

摘要： The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonist, and antagonist. The invention also provides mehtods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.

摘要翻译： 本发明提供了鉴定和编码GCREC的人G蛋白偶联受体（GCREC）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与GCREC的异常表达相关的病症的方法。