公开(公告)号：EP1356032A2

公开(公告)日：2003-10-29

申请号：EP01955908.7

申请日：2001-07-20

申请人： Incyte Genomics, Inc. ,  Thornton, Michael

发明人： YUE, Henry ,  KHAN, Farrah, A. ,  GURURAJAN, Rajagopal ,  HAFALIA, April, J., A. ,  CHAWLA, Narinder K. ,  ARVIZU, Chandra S. ,  RAMKUMAR, Jayalaxmi ,  GANDHI, Ameena, R. ,  POLICKY, Jennifer, L. ,  BAUGHN, Mariah, R. ,  TRIBOULEY, Catherine, M. ,  BANDMAN, Olga ,  NGUYEN, Danniel, B. ,  LU, Yan ,  BURFORD, Neil ,  LAL, Preeti ,  DING, Li ,  YAO, Monique, G. ,  ELLIOTT, Vicki, S. ,  RECIPON, Shirley, A. ,  KEARNEY, Liam ,  LU, Dyung, Aina, M. ,  GREENWALD, Sara, R. ,  TANG, Y., Tom ,  XU, Yuming ,  WALSH, Roderick, T. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  JACKSON, Jennifer, L. ,  THORNTON, Michael

IPC分类号： C12N15/00 ,  C12N15/54 ,  C07K16/40 ,  C12N15/63 ,  C12N9/12 ,  A61K38/45 ,  C12Q1/48 ,  C12Q1/68

CPC分类号： C12N9/1205

摘要： The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associatedd withd abberant expression of PKIN.

摘要翻译： 本发明提供了鉴定和编码PKIN的人类人类激酶（PKIN）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供了用于诊断，治疗或预防与PKIN异常表达相关的疾病的方法。

公开(公告)号：EP1390391A1

公开(公告)日：2004-02-25

申请号：EP02731927.6

申请日：2002-05-24

申请人： Incyte Genomics, Inc.

发明人： RAUMANN, Brigitte, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  BATRA, Sajeev ,  YAO, Monique, G. ,  FORSYTHE, Ian, J. ,  RAMKUMAR, Jayalaxmi ,  DUGGAN, Brendan, M. ,  BAUGHN, Mariah, R. ,  AZIMZAI, Yalda ,  WARREN, Bridget, A. ,  LAL, Preeti, G. ,  GIETZEN, Kimberly, J. ,  CHAWLA, Narinder K. ,  BECHA, Shanya, D. ,  TANG, Y., Tom ,  YUE, Henry ,  CHINN, Anna, M.

IPC分类号： C07K5/00 ,  C07K7/00 ,  C07K14/00 ,  A61K38/00

CPC分类号： C07K14/705 ,  A61K38/00 ,  A61K2039/505

摘要： The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.

公开(公告)号：EP1385977A2

公开(公告)日：2004-02-04

申请号：EP02721790.0

申请日：2002-04-19

申请人： Incyte Genomics, Inc.

发明人： KLAMMER, Aaron, A. ,  HAFALIA, April, J., A. ,  DUGGAN, Brendan, M. ,  WARREN, Bridget, A. ,  EMERLING, Brooke, M. ,  TRIBOULEY, Catherine, M. ,  ARVIZU, Chandra, S. ,  HONCHELL, Cynthia, D. ,  NGUYEN, Danniel, B. ,  KALLICK, Deborah, A. ,  YUE, Henry ,  AU-YOUNG, Janice, K. ,  RAMKUMAR, Jayalaxmi ,  LI, Joana, X. ,  THANGAVELU, Kavitha ,  GIETZEN, Kimberly, J. ,  DING, Li ,  BAUGHN, Mariah, R. ,  YAO, Monique, G. ,  CHAWLA, Narinder K. ,  MASON, Patricia M. ,  LAL, Preeti G. ,  GRAUL, Richard C. ,  REDDY, Roopa ,  BECHA, Shanya D. ,  KAREHT, Stephanie K. ,  RICHARDSON, Thomas W. ,  TRAN, Uyen K. ,  ELLIOTT, Vicki S. ,  TANG, Y. Tom ,  AZIMZAI, Yalda ,  LU, Yan ,  XU, Yuming ,  KARETH, Stephanie K.

IPC分类号： C12P21/06 ,  C12N15/85 ,  C12N15/63

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00

摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

公开(公告)号：EP1299412A2

公开(公告)日：2003-04-09

申请号：EP01948844.4

申请日：2001-06-29

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  LAL, Preeti ,  TANG, Y., Tom ,  LU, Dyung, Aina, M. ,  YAO, Monique, G. ,  NGUYEN, Danniel, B. ,  HAFALIA, April, J., A. ,  ARVIZU, Chandra, S., ,  DELEGEANE, Angelo, M. ,  BURFORD, Neil ,  POLICKY, Jennifer, L. ,  GANDHI, Ameena, R. ,  RAMKUMAR, Jayalaxmi ,  KHAN, Farrah, A. ,  THANGAVELU, Kavitha ,  XU, Yuming ,  GIETZEN, Kimberly, J. ,  CHAWLA, Narinder, K., ,  LU, Yan

IPC分类号： C07K14/00

CPC分类号： C07K14/47

摘要： The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMM.

摘要翻译： 本发明提供了识别和编码PMMM的人蛋白质修饰和维持分子（PMMM）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明提供了用于诊断，治疗或预防与PMM异常表达相关的病症的方法。

公开(公告)号：EP1521822A2

公开(公告)日：2005-04-13

申请号：EP02773383.1

申请日：2002-09-13

申请人： Incyte Genomics, Inc.

发明人： SPRAGUE, William, W. ,  CHAWLA, Narinder, K. ,  WARREN, Bridget, A. ,  TANG, Y., Tom ,  ELLIOTT, Vicki, S. ,  MARQUIS, Joseph, P. ,  LI, Joana, X. ,  GRIFFIN, Jennifer, A. ,  GIETZEN, Kimberly, J. ,  YANG, Junming ,  LU, Dyung Aina, M. ,  EMERLING, Brooke, M. ,  DUGGAN, Brendan, M. ,  RICHARDSON, Thomas, W. ,  LEE, Soo, Yeun ,  RAMKUMAR, Jayalaxmi ,  BECHA, Shanya, D. ,  LEHR-MASON, Patricia, M. ,  SWARNAKAR, Anita ,  TRAN, Uyen K. ,  KABLE, Amy E. ,  HAFALIA, April J.A. ,  KHARE, Reena

IPC分类号： C12N9/00 ,  C07H21/04

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C12N9/6421

摘要： Various embodiments of the invention provide human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.a.

公开(公告)号：EP1497315A2

公开(公告)日：2005-01-19

申请号：EP02793861.2

申请日：2002-10-29

申请人： Incyte Genomics, Inc.

发明人： BECHA, Shanya, D. ,  BOROWSKY, Mark, L. ,  BURFORD, Neil ,  CHAWLA, Narinder, K. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J., A. ,  ISON, Craig, H. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Sally ,  LEE, Soo, Yeun ,  MARQUIS, Joseph, P. ,  RAMKUMAR, Jayalaxmi ,  SPRAGUE, William, W. ,  SWARNAKAR, Anita ,  WARREN, Bridget, A. ,  TANG, Y. Tom ,  YANG, Yunming ,  YUE, Henry ,  ZEBARJADIAN, Yeganeh

IPC分类号： C07K5/00

CPC分类号： C07K14/47 ,  G01N33/6875 ,  G01N2500/04

摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

公开(公告)号：EP1487989A2

公开(公告)日：2004-12-22

申请号：EP02794113.7

申请日：2002-11-25

申请人： Incyte Genomics, Inc.

发明人： TANG, Y., Tom ,  CHAWLA, Narinder, K. ,  LU, Dyung Aina, M. ,  KHAN, Farrah, A. ,  GANDHI, Ameena, R. ,  SWARNAKAR, Anita ,  AZIMZAI, Yalda ,  MARQUIS, Joseph, P. ,  SPRAGUE, William, W. ,  EMERLING, Brooke, M. ,  YUE, Henry ,  BOROWSKY, Mark, L. ,  BECHA, Shanya, D. ,  ISON, Craig, H. ,  ELLIOTT, Vicki, S. ,  HAFALIA, April, J., A. ,  RING, Huijun, Z. ,  WARREN, Bridget, A. ,  GIETZEN, Kimberly, J. ,  TRAN, Uyen K. ,  LEE, Soo Yeun ,  LEE, Ernestine A. ,  RICHARDSON, Thomas W. ,  KABLE, Amy E. ,  BURFORD, Neil ,  LEHR-MASON, Patricia M. ,  GORVARD, Ann E. ,  LEE, Sally ,  BLAKE, Julie J. ,  HONCHELL, Cynthia D. ,  THANGAVELU, Kavitha ,  RAMKUMAR, Jayalaxmi ,  CHIEN, David ,  JIN, Pei ,  CHANG, Hsin-Ru ,  BAUGHN, Mariah R. ,  NGUYEN, Danniel B. ,  KHARE, Reena ,  BHATIA, Umesh ,  BURRILL, John D. ,  HO, Anne ,  ZHENG, Wenjin

IPC分类号： C12P21/06 ,  C12N1/20 ,  C12N15/00 ,  C07H21/02

CPC分类号： C07K14/47

摘要： Various embodiments of the invention provide human molecules for diseasedetection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.

公开(公告)号：EP1436383A2

公开(公告)日：2004-07-14

申请号：EP02725148.7

申请日：2002-03-05

申请人： Incyte Genomics, Inc.

发明人： YUE, Henry ,  YANG, Jumming ,  ELLIOTT, Vicki, S. ,  DUGGAN, Brendan, M. ,  HONCHELL, Cynthia, D. ,  LEE, Sally ,  THANGAVELU, Kavitha ,  GIETZEN, Kimberly, J. ,  FORSYTHE, Ian, J. ,  LU, Dyung, Aina, M. ,  GRIFFIN, Jennifer, A. ,  GURURAJAN, Rajagopal ,  LAL, Preeti, G. ,  BAUGHN, Mariah, R. ,  XU, Yuming ,  TANG, Y., Tom ,  AZIMZAI, Yalda ,  AU-YOUNG, Janice ,  KALLICK, Deborah, A. ,  CHAWLA, Narinder, K. ,  MASON, Patricia, M. ,  TRAN, Uyen, K.

IPC分类号： C12N9/04 ,  C12Q1/32 ,  A01N37/18

CPC分类号： C07K14/47 ,  A61K38/00 ,  C12N9/6421

摘要： The invention provides human secreted proteins (SECP) and polynucleotides which identify and encode SECP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

公开(公告)号：EP1423511A2

公开(公告)日：2004-06-02

申请号：EP02761367.8

申请日：2002-08-14

申请人： Incyte Genomics, Inc.

发明人： BARROSO, Ines ,  BAUGHN, Mariah, R. ,  BECHA, Shanya, D. ,  BLAKE, Julie, J. ,  BOROWSKY, Mark, L. ,  BURFORD, Neil ,  DUGGAN, Brendan, M. ,  ELLIOTT, Vicki, S. ,  EMERLING, Brooke, M. ,  FORSYTHE, Ian, J. ,  GIETZEN, Kimberly, J. ,  GORVAD, Ann, E. ,  GRIFFIN, Jennifer, A. ,  HAFALIA, April, J.A. ,  HONCHELL, Cynthia, D. ,  ISON, Craig, H. ,  KHAN, Farrah, A. ,  LAL, Preeti, G. ,  LEE, Ernestine, A. ,  LEE, Sally ,  LEE, Soo Yeun ,  LI, Joana X. ,  LU, Dyung Aina M. ,  LU, Yan ,  LEHR-MASON, Patricia M. ,  NGUYEN, Danniel B. ,  RAMKUMAR, Jayalaxmi ,  SPRAGUE, William W. ,  TANG, Y. Tom ,  THANGAVELU, Kavitha ,  THORNTON, Michael ,  TRAN, Uyen K. ,  CHAWLA, Narinder K. ,  WARREN, Bridget A. ,  XU, Yuming ,  YAO, Monique G. ,  YUE, Henry ,  YUE, Huibin ,  ZEBARJADIAN, Yeganeh

IPC分类号： C12N9/00 ,  C07H21/04 ,  A61K38/43

CPC分类号： C07K14/4702 ,  A61K38/00 ,  G01N2500/00

摘要： Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码NAAP的人核酸相关蛋白（NAAP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与NAAP的异常表达相关的病症的方法。

公开(公告)号：EP1417224A2

公开(公告)日：2004-05-12

申请号：EP02763529.1

申请日：2002-08-15

申请人： Incyte Genomics, Inc.

发明人： TANG, Tom, Y. ,  WARREN, Bridget, A. ,  GIETZEN, Kimberly, J. ,  LAL, Preeti, G. ,  YUE, Henry ,  HONCHELL, Cynthia, D. ,  LEHR-MASON, Patricia, M. ,  BURFORD, Neil ,  XU, Yuming ,  BAUGHN, Mariah, R. ,  DUGGAN, Brendan, M. ,  TRAN, Uyen, K. ,  LEE, Ernestine, A. ,  FORSYTHE, Ian, J. ,  RICHARDSON, Thomas, W. ,  LEE, Sally ,  THANGAVELU, Kavitha ,  YUE, Huibin ,  EMERLING, Brooke, M. ,  CHAWLA, Narinder K. ,  AZIMZAI, Yalda ,  SANJANWALA, Bharati ,  HAFALIA, April J.A. ,  BOROWSKY, Mark L. ,  NGUYEN, Danniel B. ,  ISON, Craig H. ,  ASTROMOFF, Anna ,  DING, Li ,  LEE, Soo Yeun ,  BECHA, Shanya D. ,  RAMKUMAR, Jayalaxmi ,  GANDHI, Ameena r. ,  JIN, Pei ,  FU, Glenn K. ,  SWARNAKAR, Anita

IPC分类号： C07K14/00 ,  C12P21/06 ,  A61K38/00

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/705 ,  C12N9/1205 ,  C12N9/16 ,  C12N9/6421

摘要： Various embodiments of the invention provide human secreted proteins(SECP) and polynucleotides which identify and encode SECP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of SECP.

摘要翻译： 本发明的各种实施方案提供了鉴定和编码SECP的人分泌蛋白（SECP）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其他实施方案提供了用于诊断，治疗或预防与SECP的异常表达相关的病症的方法。