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1.发明公开COMPOSITIONS COMPRISING SYNTHETIC POLYNUCLEOTIDES ENCODING CRISPR RELATED PROTEINS AND SYNTHETIC SGRNAS AND METHODS OF USE 审中-公开使用的CRISPR相关的蛋白质和合成sgRNAs和方法合成的多核苷酸编码组合物
公开(公告)号：EP3019619A4
公开(公告)日：2017-01-11
申请号：EP14823392
申请日：2014-07-11
CPC分类号： A61K48/0066 , A61K48/00 , C12N9/16 , C12N15/111 , C12N15/907 , C12N2310/10 , C12N2310/141 , C12N2310/20 , C12N2310/315 , C12N2310/346
摘要： The present invention relates to compositions comprising and methods of using synthetic polynucleotides, e.g., modified mRNA, encoding CRISPR related proteins including dCAS9 and synthetic sgRNAs targeting a gene of interest.
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公开(公告)号：EP2931914A4
公开(公告)日：2016-08-17
申请号：EP13863551
申请日：2013-12-12
发明人： BANCEL STEPHANE , DE FOUGEROLLES ANTONIN , WHORISKEY SUSAN , CHAKRABORTY TIRTHA , HUANG ERIC YI-CHUN
IPC分类号： C12P19/34
CPC分类号： C12N5/0602 , C07K14/535 , C12N9/0069 , C12N15/67 , C12N2500/40 , C12P21/00 , C12Y113/12
摘要： The present invention relates to compositions, methods and kits using cell phenotype altering polynucleotides, cell phenotype altering primary transcripts and cell phenotype altering mmRNA molecules.
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3.发明公开MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES 审中-公开修饰的多核苷酸用于化妆品的蛋白质和多肽生产
公开(公告)号：EP2833894A4
公开(公告)日：2016-08-17
申请号：EP13772947
申请日：2013-03-09
IPC分类号： A61K31/7115
CPC分类号： A61K48/0066 , A61K9/1271 , A61K9/145 , A61K9/5123 , A61K9/5146 , A61K9/5153 , A61K31/7115 , A61K38/00 , A61K38/17 , A61K38/177 , A61K38/1816 , A61K38/1891 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/45 , A61K38/4846 , A61K47/543 , A61K48/0033 , A61K48/005 , A61K48/0075 , C07H21/02 , C07K14/005 , C07K14/435 , C07K14/43595 , C07K14/47 , C07K14/4705 , C07K14/4713 , C07K14/4723 , C07K14/4746 , C07K14/475 , C07K14/485 , C07K14/495 , C07K14/505 , C07K14/515 , C07K14/525 , C07K14/535 , C07K14/5418 , C07K14/56 , C07K14/61 , C07K14/62 , C07K14/705 , C07K14/745 , C07K16/00 , C07K16/2863 , C07K16/2887 , C07K16/40 , C12N9/0069 , C12N9/0091 , C12N9/1051 , C12N9/1241 , C12N9/16 , C12N9/2402 , C12N9/2445 , C12N9/6435 , C12N9/6437 , C12N9/644 , C12N9/6443 , C12N9/6451 , C12N9/88 , C12N9/93 , C12N15/11 , C12N15/52 , C12N15/85 , C12N15/87 , C12P13/04 , C12P21/00 , C12P21/005 , C12Y113/12007 , C12Y116/03001 , C12Y207/07012 , C12Y304/21007 , C12Y304/21022 , C12Y304/21027 , C12Y403/02001 , C12Y603/02019
摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
摘要翻译： 本发明涉及组合物和方法用于制备，制造和治疗用途的多核苷酸，初级转录物和mmRNA的分子。
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公开(公告)号：EP3188749A4
公开(公告)日：2018-06-13
申请号：EP15837583
申请日：2015-09-03
CPC分类号： A61K39/39 , A61K9/14 , A61K39/0008 , A61K39/001 , A61K39/35 , A61K39/36 , A61K2039/53 , A61K2039/545 , A61K2039/55511 , A61K2039/57 , A61K2039/577 , C07K16/00 , C07K16/2809 , C07K16/2812 , C07K16/2818 , C07K16/2875
摘要： The invention relates to tolerogenic compositions and methods for the preparation, manufacture and therapeutic use thereof.
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5.发明公开POLYNUCLEOTIDES FOR THE IN VIVO PRODUCTION OF ANTIBODIES 审中-公开POLYNUKLEOTIDE ZUR in -Vivo- ERZEUGUNG VONANTIKÖRPERN
公开(公告)号：EP3092250A4
公开(公告)日：2017-05-24
申请号：EP15735068
申请日：2015-01-08
IPC分类号： C07K16/18 , A61K39/395 , C07K16/28 , C12P19/34
CPC分类号： C07K16/40 , A61K2039/53 , C07K16/18 , C07K16/24 , C07K16/28 , C07K2317/14
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