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    PRESSURE FLOW SYSTEM AND METHOD FOR TREATING A FLUID PERMEABLE WORKPIECE SUCH AS BONE
    3.
    发明公开
    PRESSURE FLOW SYSTEM AND METHOD FOR TREATING A FLUID PERMEABLE WORKPIECE SUCH AS BONE 失效
    水系是被迫和用于治疗透液性的工件，如骨

    公开(公告)号：EP0979109A1

    公开(公告)日：2000-02-16

    申请号：EP98911575.3

    申请日：1998-03-11

    申请人： Osteotech, Inc.,

    发明人： SCARBOROUGH, Nelson, L. ,  MORRIS, John, W. ,  RUSSELL, James, L. ,  DOWD, Michael

    IPC分类号： A61L27/00

    CPC分类号： A61F2/4644 ,  A61F2/28 ,  A61F2002/4646 ,  A61K35/32 ,  A61L2/0088 ,  A61L2/18 ,  A61L27/36 ,  A61L27/3608 ,  A61L27/3683 ,  Y10S623/923

    摘要： A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of providing a fluid-tight seal about the exterior of a workpiece having a non-uniform surface is positioned within the opening. Fluid under pressure is supplied to the pressure chamber to force fluid to flow through the internal matrix of the workpiece. In a preferred embodiment, the workpiece is a bone or a section thereof, and the fluid is forced to flow from the endosteal portion of bone to the periosteal portion of bone through the vasculature and porous structure of the bone to remove blood, bone marrow and/or other non-bone constituent(s) from the bone. Alternatively, the fluid can be chosen to decontaminate and/or demineralize the bone, to stain the bone to improve visualization of the bone microvasculature or to impregnate with pharmacological agents (antibiotics, bone growth factors, etc.) so that bone can act as a delivery system.

    PRESSURE FLOW SYSTEM AND METHOD FOR TREATING A FLUID PERMEABLE WORKPIECE SUCH AS BONE
    5.
    发明授权
    PRESSURE FLOW SYSTEM AND METHOD FOR TREATING A FLUID PERMEABLE WORKPIECE SUCH AS BONE 失效
    水系是被迫和用于治疗透液性的工件，如骨

    公开(公告)号：EP0979109B1

    公开(公告)日：2003-11-19

    申请号：EP98911575.3

    申请日：1998-03-11

    申请人： Osteotech, Inc.,

    发明人： SCARBOROUGH, Nelson, L. ,  MORRIS, John, W. ,  RUSSELL, James, L. ,  DOWD, Michael

    IPC分类号： A61L27/00

    CPC分类号： A61F2/4644 ,  A61F2/28 ,  A61F2002/4646 ,  A61K35/32 ,  A61L2/0088 ,  A61L2/18 ,  A61L27/36 ,  A61L27/3608 ,  A61L27/3683 ,  Y10S623/923

    摘要： A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of providing a fluid-tight seal about the exterior of a workpiece having a non-uniform surface is positioned within the opening. Fluid under pressure is supplied to the pressure chamber to force fluid to flow through the internal matrix of the workpiece. In a preferred embodiment, the workpiece is a bone or a section thereof, and the fluid is forced to flow from the endosteal portion of bone to the periosteal portion of bone through the vasculature and porous structure of the bone to remove blood, bone marrow and/or other non-bone constituent(s) from the bone. Alternatively, the fluid can be chosen to decontaminate and/or demineralize the bone, to stain the bone to improve visualization of the bone microvasculature or to impregnate with pharmacological agents (antibiotics, bone growth factors, etc.) so that bone can act as a delivery system.

    FUSION IMPLANT DEVICE AND METHOD OF USE
    6.
    发明公开
    FUSION IMPLANT DEVICE AND METHOD OF USE 失效
    植入装置椎融合及使用方法

    公开(公告)号：EP1014900A1

    公开(公告)日：2000-07-05

    申请号：EP97942528.7

    申请日：1997-09-17

    申请人： Osteotech, Inc.,

    发明人： SCARBOROUGH, Nelson ,  MORRIS, John, W.

    IPC分类号： A61F2/44

    CPC分类号： A61F2/447 ,  A61F2/446

    摘要： An intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae and having at least first and second longitudinal sections with respective first and second cross-sectional dimensions. The first cross-sectional dimension of the first implant section is greater than the second cross section dimension of the second implant section to define a stepped region having a retaining surface. Consequently, upon insertion of the implant member within a generally correspondingly dimensioned receiving bed formed within the adjacent vertebrae, the retaining surface facilitates securement therewithin by corresponding engagement with surfaces of the receiving bed. A method for fusion of adjacent vertebrae utilizing the prosthesis is also disclosed.

    CLEANING OF A BONE WORKPIECE BY PULSATILE PRESSURE
    10.
    发明公开
    CLEANING OF A BONE WORKPIECE BY PULSATILE PRESSURE 审中-公开
    CLEANING骨的工件，脉动

    公开(公告)号：EP1253949A1

    公开(公告)日：2002-11-06

    申请号：EP01909046.3

    申请日：2001-02-09

    申请人： Osteotech, Inc.,

    发明人： MORRIS, John, W. ,  SHIMP, Lawrence, A. ,  RUSSELL, James ,  SCARBOROUGH, Nelson, L.

    IPC分类号： A61L2/00

    CPC分类号： A61L2/0005 ,  A61L2/0088

    摘要： There is provided a pulsatile flow pressure system for treating tissue, such as, for example, bone tissue. This system generally includes one, and preferably two, pressure chambers configured to receive the natural ends of intact bone. Alternate positive and negative pressures are enacted on the bone ends to force fluid into the bone and substantially out through an exterior surface thereof. Alternatively, both ends of an intact bone can be positioned in separate pressure chambers and simultaneous positive or negative pressures applied to the bone ends to force fluid through the bone tissue.