专利检索 ap:("Pharmasset, Inc.") AND inv:"PAMULAPATI, Ganapati, Reddy" 第 1 页

1.

发明公开
NUCLEOSIDE CYCLICPHOSPHATES 有权
标题翻译：环磷酸核苷

公开(公告)号：EP2313422A2

公开(公告)日：2011-04-27

申请号：EP09763386.1

申请日：2009-06-08

申请人： Pharmasset, Inc.

发明人： DU, Jinfa , NAGARATHNAM, Dhanapalan , PAMULAPATI, Ganapati, Reddy , ROSS, Bruce, S. , SOFIA, Michael, Joseph

IPC分类号： C07H19/10 , C07H19/20 , C07D473/18

CPC分类号： C07D473/18 , C07H19/10 , C07H19/20

摘要： Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following structure: Formula (I)

2.

发明公开
N- [ (2 ' R) -2 ' -DEOXY-2 ' -FLUORO-2 ' -METHYL-P-PHENYL-5 ' -URIDYLYL]-L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION 有权
标题翻译： N个制造方法 - [（2'R）-2'-脱氧-2'-氟-2'-甲基 - 对 - 苯基-5“-URIDYLYL] -L-丙氨酸1-甲基乙基酯

公开(公告)号：EP2432792A1

公开(公告)日：2012-03-28

申请号：EP10721225.0

申请日：2010-05-20

申请人： Pharmasset, Inc.

发明人： ROSS, Bruce, S. , SOFIA, Michael, Joseph , PAMULAPATI, Ganapati, Reddy , RACHAKONDA, Suguna , ZHANG, Hai-ren , CHUN, Byoung-kwon , WANG, Peiyuan

IPC分类号： C07H19/10 , C07H19/073 , A61K31/7072 , A61P31/14

CPC分类号： C07H19/10 , A61K31/7072 , A61K31/716 , A61K45/00 , C07F9/24 , C07F9/242 , C07F9/65586 , C07H1/00 , C07H17/02 , Y02A50/463 , Y02P20/55

摘要： Disclosed herein are nucleoside phosphoramidates of formula 4 and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.

3.

发明公开
Synthesis of purine nucleosides 审中-公开
标题翻译：嘌呤核苷的合成

公开(公告)号：EP2376515A1

公开(公告)日：2011-10-19

申请号：EP09793688.4

申请日：2009-12-23

申请人： Pharmasset, Inc.

发明人： CHUN, Byoung-kwon , DU, Jinfa , RACHAKONDA, Suguna , ROSS, Bruce, S. , SOFIA, Michael, Joseph , PAMULAPATI, Ganapati, Reddy , CHANG, Wonsuk , ZHANG, Hai-ren , NAGARATHNAM, Dhanapalan

IPC分类号： C07H19/167 , C07H19/20 , C07H19/213 , A61K31/7076 , A61P31/14

CPC分类号： C07H19/20 , C07H1/00 , C07H5/02 , C07H15/04 , C07H19/167 , C07H19/213 , Y02P20/55

摘要： A process for preparing phosphoramidate prodrugs or cyclic phosphate prodrugs of nucleoside derivatives, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof.