-
1.发明公开AMIDE AND UREA DERIVATIVES FOR THE TREATMENT OF METABOLIC DISEASES 审中-公开AMID- UND HARNSTOFFDERIVATE ZUR BEHANDLUNG VON STOFFWECHSELERKRANKUNGEN
公开(公告)号：EP2120911A1
公开(公告)日：2009-11-25
申请号：EP08709623.6
申请日：2008-02-15
Applicant: Prosidion Limited
Inventor： BARBA, Oscar , DAWSON, Graham , GATTRELL, William , PROCTER, Martin, James , RASAMISON, Chrystelle, Marie , SAMBROOK-SMITH, Colin, Peter , WONG-KAI-IN, Philippe
IPC: A61K31/165 , A61K31/17 , C07C237/24 , C07C275/42 , A61P3/04 , A61K31/41 , A61K31/435 , C07D207/08 , C07D207/16 , C07D207/34 , C07D209/42 , C07D213/72 , C07D213/81 , C07D213/82 , C07D215/04
CPC classification number: C07D207/08 , C07C233/81 , C07C235/66 , C07C237/24 , C07C275/34 , C07C275/42 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07D207/16 , C07D207/34 , C07D209/42 , C07D213/72 , C07D213/81 , C07D213/82 , C07D215/04 , C07D215/48 , C07D215/54 , C07D217/26 , C07D231/14 , C07D231/56 , C07D233/64 , C07D235/24 , C07D241/28 , C07D241/44 , C07D249/10 , C07D261/08 , C07D261/18 , C07D261/20 , C07D277/56 , C07D277/64 , C07D295/00 , C07D307/85 , C07D317/60 , C07D319/18 , C07D319/20 , C07D333/70 , C07D401/08 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04
Abstract: Compounds of formula (I): or pharmaceutically acceptable salts and esters thereof, are useful for the treatment of obesity, type II diabetes and the metabolic syndrome.
Abstract translation: 式（I）化合物或其药学上可接受的盐和酯可用于治疗肥胖，II型糖尿病和代谢综合征。
-
2.发明公开PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE 有权吡咯并吡啶-2-羧酸作为糖原磷酸化酶的抑制剂
公开(公告)号：EP1636224A2
公开(公告)日：2006-03-22
申请号：EP04753127.2
申请日：2004-05-20
Applicant: Prosidion Limited
Inventor： BRADLEY, Stuart, Edward , KRULLE, Thomas, Martin , MURRAY, Peter, John , PROCTER, Martin, James , ROWLEY, Robert, John , SAMBROOK SMITH, Colin, Peter , THOMAS, Gerard, Hugh , SCHOFIELD, Karen, Lesley
IPC: C07D471/00 , C07D519/00 , A61K31/437 , A61P9/10
CPC classification number: C07D471/04
Abstract: Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.
-
公开(公告)号：EP1594863A1
公开(公告)日：2005-11-16
申请号：EP04709897.5
申请日：2004-02-10
Applicant: Prosidion Limited
Inventor： FYFE, Matthew, Colin, Thor , GARDNER, Lisa, Sarah , NAWANO, Masao , PROCTER, Martin, James , WILLIAMS, Geoffrey, Martyn , WITTER, David , YASUDA, Kosuke , RASAMISON, Chrystelle, Marie , CASTELHANO, Arlindo
IPC: C07D405/08 , C07D213/74 , C07D213/75 , C07D401/12 , C07D401/04 , C07D413/12 , C07D417/12 , C07D417/14 , C07D213/61 , C07D213/70 , C07D239/38 , A61K31/4439 , A61P3/10
CPC classification number: C07D401/04 , C07D213/55 , C07D213/61 , C07D213/70 , C07D213/75 , C07D239/38 , C07D401/12 , C07D413/12 , C07D417/12 , C07D417/14
Abstract: Compounds of Formula (I): (I) or pharmaceutically acceptable salts or N-oxides thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
-
4.发明授权PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE 有权吡咯并吡啶-2-羧酸作为糖原磷酸化酶的抑制剂
公开(公告)号：EP1636224B1
公开(公告)日：2010-07-14
申请号：EP04753127.2
申请日：2004-05-20
Applicant: Prosidion Limited
Inventor： BRADLEY, Stuart, Edward , KRULLE, Thomas, Martin , MURRAY, Peter, John, c/o Patents Department , PROCTER, Martin, James , ROWLEY, Robert, John , SAMBROOK SMITH, Colin, Peter , THOMAS, Gerard, Hugh , SCHOFIELD, Karen, Lesley
IPC: C07D471/00 , C07D519/00 , A61K31/437 , A61P9/10
CPC classification number: C07D471/04
Abstract: Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.
-
公开(公告)号：EP2200609A1
公开(公告)日：2010-06-30
申请号：EP08806639.4
申请日：2008-09-10
Applicant: Prosidion Limited
Inventor： BARBA, Oscar , BRADLEY, Stuart, Edward , FYFE, Matthew, Colin, Thor , HANRAHAN, Patrick, Eric , KRULLE, Thomas, Martin , PROCTER, Martin, James , REYNET MCCORMACK, Christine , SCHOFIELD, Karen, Lesley , SMYTH, Donald , STEWART, Alan, John, William , SWAIN, Simon, Andrew , WIDDOWSON, Peter
IPC: A61K31/44 , A61P3/04 , A61P3/10 , C07D401/12 , C07D403/14 , C07D413/14 , C07D417/14
CPC classification number: C07D401/12 , C07D211/18 , C07D211/22 , C07D401/14 , C07D413/04 , C07D413/14 , C07D417/12 , C07D417/14
Abstract: The present invention is directed to therapeutic compounds which have dual activity as agonists of GPR119 and inhibitors of DPP-IV and are useful for the treatment of metabolic disorders including type II diabetes.
Abstract translation: 本发明涉及具有作为GPR119激动剂和DPP-IV抑制剂双重活性的治疗性化合物，并且可用于治疗包括II型糖尿病的代谢病症。
-
Patent Agency Ranking
公开(公告)号：EP2406247A1
公开(公告)日：2012-01-18
申请号：EP10709925.1
申请日：2010-03-12
Applicant: Prosidion Limited
Inventor： BARBA, Oscar , FRY, Peter, Timothy , FYFE, Matthew, Colin, Thor , GATTRELL, William , JEEVARATNAM, Revathy, Perpetua , KRULLE, Thomas, Martin , PROCTER, Martin, James , SAMBROOK-SMITH, Colin, Peter , SCHOFIELD, Karen, Lesley , SMYTH, Donald , STEWART, Alan, John, William , STONEHOUSE, David, French , SWAIN, Simon, Andrew
IPC: C07D401/12 , C07D401/14 , C07D403/14 , C07D413/14 , A61K31/4523 , A61K31/397 , A61P3/00
CPC classification number: C07D401/12 , C07D213/64 , C07D401/14 , C07D403/14 , C07D413/14
Abstract: The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes (I).
Abstract translation: 本发明涉及具有GPR119激动剂活性并可用于治疗包括II型糖尿病（I）的代谢病症的治疗性化合物。
-
7.发明公开BICYCLIC ARYL AND HETEROARYL RECEPTOR MODULATORS 审中-公开BICYCLISCHE ARYL- UND HETEROARYLVERBINDUNGEN ALS REZEPTORMODULATOREN
公开(公告)号：EP2197835A1
公开(公告)日：2010-06-23
申请号：EP08788771.7
申请日：2008-09-08
Applicant: Prosidion Limited
Inventor： BLOXHAM, Jason , BRADLEY, Stuart, Edward , KRULLE, Thomas, Martin , PROCTER, Martin, James , SAMBROOK-SMITH, Colin, Peter , SCHOFIELD, Karen, Lesley , SMYTH, Donald
IPC: C07C237/30 , C07D213/56 , C07D333/20 , C07D333/58 , A61K31/166 , A61K31/381 , A61K31/451 , A61P3/04
CPC classification number: C07C237/30 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2602/42 , C07C2603/74 , C07D213/56 , C07D333/20 , C07D333/58
Abstract: Compounds of formula (I) or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful inter alia for the treatment of obesity.
Abstract translation: 式（I）化合物或其药学上可接受的盐是阿片样物质受体调节剂，例如 μ-阿片受体拮抗剂，中性拮抗剂或反向激动剂，并且尤其用于治疗肥胖症。
-
公开(公告)号：EP1907384A2
公开(公告)日：2008-04-09
申请号：EP06744357.2
申请日：2006-06-29
Applicant: Prosidion Limited
Inventor： BRADLEY, Stuart, Edward , FYFE, Matthew, Colin, Thor , BERTRAM, Lisa, Sarah , GATTRELL, William , PROCTER, Martin, James , RASAMISON, Chrystelle, Marie , SAMBROOK-SMITH, Colin, Peter , SHAH, Vilasben, Kanji , STONEHOUSE, David, French , SWAIN, Simon, Andrew , THOMAS, Gerard, Hugh
IPC: C07D413/14 , C07D471/04 , C07D495/04 , C07D417/14
CPC classification number: C07D471/04 , C07D405/06 , C07D405/12 , C07D413/14 , C07D417/14 , C07D495/04
Abstract: Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
-
公开(公告)号：EP1594867A2
公开(公告)日：2005-11-16
申请号：EP04707845.6
申请日：2004-02-10
Applicant: Prosidion Limited
Inventor： FYFE, Matthew, Colin, Thor , GARDNER, Lisa, Sarah , NAWANO, Masao , PROCTER, Martin, James , RASAMISON, Chrystelle, Marie , SCHOFIELD, Karen, Lesley , SHAH, Vilasben, Kanji , YASUDA, Kosuke
IPC: C07D417/12 , C07D405/12 , C07D413/12 , C07D277/46 , C07D417/14 , C07D491/08 , A61K31/427 , A61K31/4439 , A61K31/454 , A61K31/495 , A61P3/10 , C07D309/04 , C07D277/40
CPC classification number: C07D231/12 , C07D211/34 , C07D213/55 , C07D233/56 , C07D249/08 , C07D277/30 , C07D277/40 , C07D277/46 , C07D307/54 , C07D309/04 , C07D309/08 , C07D333/24 , C07D333/28 , C07D335/02 , C07D405/10 , C07D405/12 , C07D407/12 , C07D409/10 , C07D413/12 , C07D417/12 , C07D417/14 , C07D491/08
Abstract: Compounds of Formula (I): or pharmaceutically acceptable salts thereof, are useful in the prophylactic and therapeutic treatment of hyperglycemia and diabetes.
-
10.发明公开BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开双环芳基和杂芳基的代谢障碍的治疗
公开(公告)号：EP2152671A1
公开(公告)日：2010-02-17
申请号：EP08750765.3
申请日：2008-05-22
Applicant: Prosidion Limited
Inventor： BLOXHAM, Jason , BRADLEY, Stuart, Edward , DUPREE, Tom, Banksia , FRY, Peter, Timothy , HANRAHAN, Patrick, Eric , KRULLE, Thomas, Martin , PROCTER, Martin, James , SAMBROOK-SMITH, Colin, Peter , SCHOFIELD, Karen, Lesley , SMYTH, Donald , STEWART, Alan, John, William
IPC: C07D213/62 , C07D401/12 , C07D405/12 , C07D409/12 , A61K31/44 , A61P3/04
CPC classification number: C07D213/62 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu- opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.017 seconds)
