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1.发明授权
公开(公告)号：EP2981166B1
公开(公告)日：2020-09-09
申请号：EP14778180.1
申请日：2014-04-02
发明人： AINLEY, W. Michael , GUSCHIN, Dmitry Y. , HAYDEN, Matthew , ISENEGGER, Daniel , MASON, John , MILLER, Jeffrey C. , PETOLINO, Joseph F. , RAN, Yidong , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R.
IPC分类号： A01H1/00
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公开(公告)号：EP2893006B1
公开(公告)日：2018-08-22
申请号：EP13834682.0
申请日：2013-09-05
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R. , GUPTA, Manju , AINLEY, William Michael , HENRY, Matthew J. , MILLER, Jeffrey C. , GUSCHIN, Dmitry Y.
IPC分类号： C12N5/10
CPC分类号： C12N15/79 , C12N9/22 , C12N15/63 , C12N15/8241 , C12N15/8247
摘要： A method of gene editing or gene stacking within a FAD3 loci by cleaving, in a site directed manner, a location in a FAD3 gene in a cell, to generate a break in the FAD3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.
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公开(公告)号：EP2847338B1
公开(公告)日：2018-09-19
申请号：EP13788413.6
申请日：2013-05-07
发明人： COST, Gregory, J. , URNOV, Fyodor , AINLEY, William M. , PETOLINO, Joseph F. , SAMUEL, Jayakumar Pon , WEBB, Steven R. , SASTRY-DENT, Lakshmi
CPC分类号： C12N15/8201 , C12N15/102 , C12N15/8209 , C12N15/8213 , C12N15/8216 , C12N15/8241 , C12N15/8247 , C12N15/8274 , C12N15/8278 , C12N15/8286 , C12N15/85 , C12N15/87 , C12N2800/80 , Y02A40/162
摘要： Disclosed herein are methods and compositions for homology-independent targeted insertion of donor molecules into the genome of a cell.
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公开(公告)号：EP2892321B1
公开(公告)日：2018-10-24
申请号：EP13834776.0
申请日：2013-09-05
发明人： AINLEY, William Michael , WEBB, Steven R. , SAMUEL, Pon , GUSCHIN, Dmitry Y. , MILLER, Jeffrey C. , ZHANG, Lei
CPC分类号： C12N15/8216 , C07K14/4702 , C07K2319/81 , C12N9/22 , C12N15/102 , C12N15/66 , C12N15/822 , C12N15/8247 , C12N15/902 , C12Y301/00
摘要： A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break in the FAD2 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.
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公开(公告)号：EP3862434A1
公开(公告)日：2021-08-11
申请号：EP21156805.0
申请日：2014-11-03
申请人： Dow AgroSciences LLC
发明人： SASTRY-DENT, Lakshmi , CAO, Zehui , SRIRAM, Shreedharan , WEBB, Steven R. , CAMPER, Debra L. , AINLEY, William Michael
摘要： As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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6.发明公开METHODS AND COMPOSITIONS FOR INTEGRATION OF AN EXOGENOUS SEQUENCE WITHIN THE GENOME OF PLANTS 审中-公开方法和组合物外源序列在植物的基因组整合
公开(公告)号：EP2981166A2
公开(公告)日：2016-02-10
申请号：EP14778180.1
申请日：2014-04-02
发明人： AINLEY, W. Michael , GUSCHIN, Dmitry Y. , HAYDEN, Matthew , ISENEGGER, Daniel , MASON, John , MILLER, Jeffrey C. , PETOLINO, Joseph F. , RAN, Yidong , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R.
IPC分类号： A01H1/00
摘要： Disclosed herein are methods and compositions for parallel or sequential transgene stacking in plants to produce plants with selected phenotypes.
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公开(公告)号：EP2931950A1
公开(公告)日：2015-10-21
申请号：EP13861906.9
申请日：2013-12-13
申请人： Dow AgroSciences LLC
发明人： SASTRY-DENT, Lakshmi , SIMPSON, Matthew , CAO, Zehui , CHEN, Wei , ZHOU, Ning , WEBB, Steven R.
CPC分类号： C12Q1/6858 , A01G24/00 , C12N5/00 , C12N15/1082 , C12N15/66 , C12N15/70 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C40B40/08
摘要： The present disclosure provides methods for detecting and identifying plant events that contain precision targeted genomic loci, and plants and plant cells comprising such targeted genomic loci. The method can be deployed as a high throughput process utilized for screening the intactness or disruption of a targeted genomic loci and optionally for detecting a donor DNA polynucleotide insertion at the targeted genomic loci. The methods are readily applicable for the identification of plant events produced via a targeting method which results from the use of a site specific nuclease.
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8.发明公开PRODUCTION OF FUNCTIONALIZED LINEAR DNA CASSETTE AND QUANTUM DOT/NANOPARTICLE MEDIATED DELIVERY IN PLANTS 审中-公开的一种线性官能化DNA盒及其量子DOT /纳米颗粒介导的递送植物中
公开(公告)号：EP2591115A2
公开(公告)日：2013-05-15
申请号：EP11804352.0
申请日：2011-07-07
申请人： Dow AgroSciences LLC
发明人： YAU, Kerrm Y. , SAMUEL, Jayakumar Pon , BURROUGHS, Frank G. , SAMBOJU, Narasimha Chary , WEBB, Steven R.
CPC分类号： C12N15/8206 , B82Y5/00 , C12N15/8201 , C12N15/8207 , C12N15/87 , C12Q2600/13
摘要： Methods for introducing a functionalized linear nucleic acid cassette molecule of interest into a plant cell comprising a cell wall include use of nanoparticles. In some embodiments, the cell comprising a cell wall is a cultured plant cell. Methods include genetically or otherwise modifying plant cells and for treating or preventing disease in any plant, especially crop plants. Transgenic plants include a nucleic acid molecule of interest produced by regeneration of whole plants from plant cells transformed with functionalized linear nucleic acid cassette molecules.
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公开(公告)号：EP2893025B1
公开(公告)日：2019-03-13
申请号：EP13835965.8
申请日：2013-09-06
申请人： Dow AgroSciences LLC
发明人： COGAN, Noel , FORSTER, John , HAYDEN, Matthew , SAWBRIDGE, Tim , SPANGENBERG, German , WEBB, Steven R. , GUPTA, Manju , AINLEY, W. Mike , HENRY, Matthew J. , MASON, John , KUMAR, Sandeep , NOVAK, Stephen
IPC分类号： C12N5/10
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公开(公告)号：EP3065540A2
公开(公告)日：2016-09-14
申请号：EP14857141.7
申请日：2014-11-03
发明人： SASTRY-DENT, Lakshmi , CAO, Zehui , SRIRAM, Shreedharan , WEBB, Steven R. , CAMPER, Debra L. , ELANGO, Navin
CPC分类号： C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
摘要： As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.
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