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26 条记录 (耗时 0.013 秒)

    A method for detection of carcinoembryonic antigens having a modified sugar chain structure
    1.
    发明公开
    A method for detection of carcinoembryonic antigens having a modified sugar chain structure 审中-公开
    一种用于检测癌胚抗原的具有修饰的糖链结构的方法

    公开(公告)号：EP1061370A2

    公开(公告)日：2000-12-20

    申请号：EP00112207.6

    申请日：2000-06-07

    申请人： Wako Pure Chemical Industies, Ltd.

    发明人： Hosokawa, Hideaki ,  Nakamura, Kenji ,  Satomura, Shinji

    IPC分类号： G01N33/574

    CPC分类号： G01N33/57473 ,  G01N2400/02

    摘要： The present invention relates to a method for detection of carcinoembryonic antigens (hereinafter abbreviated as CEAs) having a modified sugar chain structure which comprises using an antibody against a constant region of CEAs and a protein capable of recognizing a modified sugar chain structure of CEAs, a method for detecting a cancer which comprises using an amount of CEAs having a modified sugar chain structure and a kit for detection of CEAs having a modified sugar chain structure which comprises an antibody against a constant region of CEAs and a protein capable of recognizing a modified sugar chain structure of CEAs.
    Said method and kit are useful in a separately measurement of the various CEAs, a detection of a cancer and a definition of the kind of a cancer, and, for example, by using in proper combination of the measurement value of various CEAs obtained by the method of the present invention, it becomes possible to detect the cancer or define the kind of the cancer.

    摘要翻译： 本发明涉及一种用于检测癌胚抗原的方法（在后缩写为CEA）具有包括使用抗体对CEA的恒定区，并且能够认识到CEAS的经修饰的糖链结构的蛋白，其修饰的糖链结构，一个 用于检测包括使用达CEAS的具有修饰的糖链结构和用于检测CEAS的具有修饰的糖链结构，其抗体对CEA的恒定区和蛋白包含能够识别经修饰的糖的试剂盒的癌症的方法 CEAS的链结构。 所述方法和试剂盒是在一个单独的测量的各种CEAS，癌症的检测和种类的癌症的定义，是有用的，并且，例如，通过使用由所述获得的各种CEAS的测量值的适当组合 本发明的方法，能够检测出癌症或限定的种类，癌症的。

    Macroazo compounds comprising silicone and polyether structures
    2.
    发明公开
    Macroazo compounds comprising silicone and polyether structures 有权
    硅和聚醚 - 结构物Makroazo-Verbindungen

    公开(公告)号：EP0967238A1

    公开(公告)日：1999-12-29

    申请号：EP99111844.9

    申请日：1999-06-19

    申请人： Wako Pure Chemical Industies, Ltd.

    发明人： Shiraki, Kazuo ,  Tsurumoto, Hiroyuki ,  Abe, Tomomitsu

    IPC分类号： C08G77/46

    CPC分类号： C08G77/46

    摘要： Macroazo compounds, which comprise a repeating unit composed of a moiety of the formula (a), a moiety of the formula (b) and a moiety of the formula (c)
    wherein X, E, Z and T are independently a lower alkylene group, R 1 , R 2 , R 3 and R 4 are independently a lower alkyl group or a cyano group, R 5 , R 6 , R 7 and R 8 are independently a lower alkyl group or an aryl group, and m and n are independently a positive integer, those moieties being bound with one another through a carboxylic acid ester linkage or a carboxylic acid amido linkage, make it possible, for instance, in a case of using the compound as a polymerization initiator, to produce easily and at high efficiency a block polymer containing both polyorganosiloxane units and polyoxyalkylene units in its molecule.

    摘要翻译： 大分子化合物，其包含由式（a）部分组成的重复单元，式（b）的部分和式（c）的部分，其中X，E，Z和T独立地为 低级亚烷基，R 1，R 2，R 3和R 4独立地为低级烷基或氰基，R 5，R 6，R 7和R <8>独立地是低级烷基或芳基，m和n独立地是正整数，这些部分通过羧酸酯键或羧酸酰胺键彼此结合，例如可以 在使用该化合物作为聚合引发剂的情况下，在分子中容易且高效率地制备含有聚有机硅氧烷单元和聚氧化烯单元的嵌段聚合物。

    Azoamide compounds and their use as polymerisation initiators
    3.
    发明公开
    Azoamide compounds and their use as polymerisation initiators 有权
    Azoamid-Verbindungen und ihre Anwendung als Polymerisationsinitiatoren

    公开(公告)号：EP0957114A1

    公开(公告)日：1999-11-17

    申请号：EP99109142.2

    申请日：1999-05-08

    申请人： Wako Pure Chemical Industies, Ltd.

    发明人： Kondo, Suguru ,  Hirose, Seiji ,  Shiraki, Kazuo

    IPC分类号： C08F4/04 ,  C07C245/04 ,  C07C255/65

    CPC分类号： C08F4/04 ,  C07C245/04 ,  C07C255/65

    摘要： A compound shown by the general formula [1]
    wherein R 1 and R 2 are independently a Lower alkyl group or a cyano group, R 3 is a lower alkyl group and X is a lower alkylene group, showing high solubility into various kinds of polar solvents and are capable of effectively introducing hydroxy groups into terminal positions of polymers and their use.

    摘要翻译： 由通式Ä1Ü表示的化合物，其中R 1和R 2独立地为低级烷基或氰基，R 3为低级烷基，X为低级亚烷基，显示 能够高分子量地溶解于各种极性溶剂中，能够有效地将羟基引入到聚合物的末端位置及其用途。

    PALLADIUM CATALYST COMPOSITION
    4.
    发明公开
    PALLADIUM CATALYST COMPOSITION 有权
    PALLADIUMKATALYSATORZUSAMMENSETZUNG

    公开(公告)号：EP1537913A1

    公开(公告)日：2005-06-08

    申请号：EP03795271.0

    申请日：2003-09-01

    申请人： Wako Pure Chemical Industies, Ltd. ,  JAPAN SCIENCE AND TECHNOLOGY CORPORATION

    发明人： KOBAYASHI, Shu ,  SANO, Atsunori ,  OONO, Keiji

    IPC分类号： B01J31/28 ,  C07C45/62 ,  C07C49/213 ,  C07C67/343 ,  C07C69/618 ,  C07C69/757 ,  C07C41/16 ,  C07C43/215 ,  C07C45/29 ,  C07C47/232 ,  C07C205/34 ,  C07C201/12 ,  C07B61/00

    CPC分类号： B01J31/06 ,  B01J2231/44 ,  B01J2231/645 ,  B01J2231/70 ,  C07B2200/11 ,  C07C17/16 ,  C07C41/16 ,  C07C45/29 ,  C07C45/62 ,  C07C67/343 ,  C07D303/16 ,  C07F15/006 ,  C07F15/0066 ,  C07C22/04 ,  C07C47/232 ,  C07C49/213 ,  C07C69/618 ,  C07C43/215

    摘要： The present invention discloses 1) a catalyst composition consisting of a crosslinked organic polymer compound and a palladium catalyst, wherein said catalyst is physically carried on said crosslinked organic polymer compound, 2) a manufacturing method of the above catalyst composition 1), characterized by homogenizing a straight chain organic polymer compound, having a crosslinkable functional group, and a palladium catalyst in a solvent dissolving said straight chain organic polymer compound, then depositing a composition thus formed and subjecting the crosslinkable functional group in said deposit to a crosslinking reaction, 3) a method for substitution reaction at an allyl position, characterized by reacting an allyl carbonate and a neucleophilic agent in the presence of the above catalyst composition 1), and 4) a method for oxidizing an alcohol, characterized by subjecting the above catalyst composition 1) to reaction with an alcohol. The catalyst composition of the present invention can be safely and easily handled without danger of spontaneous ignition, and the like, and is extremely useful as a catalyst for various chemical reactions, and further activity thereof is not decreased by repeated use thereof and a metal catalyst does not leak from a polymer compound which is a carrier thereof.

    摘要翻译： 本发明公开了1）由交联的有机高分子化合物和钯催化剂组成的催化剂组合物，其中所述催化剂在所述交联的有机高分子化合物上物理运载，2）上述催化剂组合物1）的制备方法， 具有可交联官能团的直链有机高分子化合物和溶解所述直链有机高分子化合物的溶剂中的钯催化剂，然后沉积由此形成的组合物，并对所述沉积物中的交联性官能团进行交联反应; 3） 在烯丙基位置进行取代反应的方法，其特征在于在上述催化剂组合物1）的存在下使碳酸烯丙酯和亲核试剂反应，和4）一种氧化醇的方法，其特征在于将上述催化剂组合物1） 与酒精反应。 本发明的催化剂组合物可以安全，容易地处理而没有自发点火的危险等，并且作为各种化学反应的催化剂是非常有用的，并且通过反复使用和金属催化剂不会降低其进一步的活性 不会从作为其载体的高分子化合物泄漏。

    Method for measuring thyroglobulin
    9.
    发明公开
    Method for measuring thyroglobulin 有权
    Methode zur Messung von Thyroglobulin

    公开(公告)号：EP0973038A1

    公开(公告)日：2000-01-19

    申请号：EP99112316.7

    申请日：1999-06-26

    申请人： Wako Pure Chemical Industies, Ltd.

    发明人： Kato, Ryoji ,  Maruyama, Masayuki ,  Nakamura, Kenji ,  Shimizu, Kayoko ,  Satomura, Shinji

    IPC分类号： G01N33/78 ,  G01N33/566

    CPC分类号： G01N33/78 ,  G01N33/574 ,  G01N2333/71

    摘要： A method for measuring thyroglobulin(s), comprising using each one or more kinds of proteins capable of binding to a constant region of thyroglobulin(s) and proteins capable of specifically binding to a specific sugar chain structure of thyroglobulin(s) having the specific sugar chain structure, and the method of determining a malignancy of thyroid tumor, a reagent thereof using the obtained by the method for measuring thyroglobulin(s).

    摘要翻译： 一种测定甲状腺球蛋白的方法，其包括使用能够结合甲状腺球蛋白的恒定区域的能够与特异性结合甲状腺球蛋白的特定糖链结构的每种一种或多种蛋白质， 糖链结构以及使用通过测定甲状腺球蛋白的方法得到的试剂来测定甲状腺肿瘤恶性的方法。