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    Improved flow cytometer nozzle and flow cytometer sample handling methods
    8.
    发明公开
    Improved flow cytometer nozzle and flow cytometer sample handling methods 有权
    Durchflusszytometerdüse和Durchflusszytometerprobenbehandlungsverfahren

    公开(公告)号：EP2264430A3

    公开(公告)日：2014-05-14

    申请号：EP10182264.1

    申请日：2000-11-29

    申请人： XY, LLC

    发明人： Buchanan, Kristopher S. ,  Herickhoff, Lisa

    IPC分类号： G01N15/14 ,  G01N15/00 ,  G01N15/10

    CPC分类号： G01N15/1404 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1409 ,  G01N2015/1413 ,  G01N2015/1415 ,  G01N2015/149 ,  Y10T436/101666

    摘要： A flow cytometer system, comprising a sample injection tube having an injection point through which a sample may be introduced, a sheath fluid container having a bottom end and wherein said sample injection tube is located within said sheath fluid container, a sheath fluid port connected to said sheath fluid container, a first axial motion surface in a nozzle, a second axial motion surface in said nozzle, a limited maximal acceleration differentiation transition area between said first axial motion surface in said nozzle and said second axial motion surface in said nozzle wherein said limited maximal acceleration differentiation transition area is coordinated with said sample so as to be affirmatively limited to not exceed the practical capabilities of said sample over its length and an analytical system which senses below said nozzle.

    摘要翻译： 已经发明了一种用于流式细胞仪的改进的喷嘴系统，用于平坦样品的高效取向和分选过程，并且专用诸如马或牛精子细胞的物品。 这种改进的喷嘴系统包括具有新颖的内表面几何形状的喷嘴（16），其可以轻轻地加速细胞并且可以在（c）喷嘴内包括椭圆形的单个扭转内表面元件，即单个扭转定向喷嘴 （6）。 椭圆形的单个扭转内表面元件（例如）（8,9,10）可以具有层流表面并且可以产生最简单的流动路径，用于施加以加速性质或取向的流体动力作用的最小力，即 单一的扭转取向力将诸如动物精子细胞的平坦样品（16）定向到正确的方向，以便在临床应用中进行分析和有效分选过程，用于研究和动物授精行业。

    Sex-specific insemination of mammals with low number of sperm cells
    9.
    发明公开
    Sex-specific insemination of mammals with low number of sperm cells 有权
    哺乳动物的性别特异性受精精子数量少

    公开(公告)号：EP2341129A3

    公开(公告)日：2013-11-06

    申请号：EP10185715.9

    申请日：1998-12-31

    申请人： XY, LLC

    发明人： Seidel, George E. ,  Herickhoff, Lisa ,  Schenk, John

    IPC分类号： C12N5/076 ,  A61D19/02 ,  A01K67/02 ,  A01K67/027 ,  C12N15/873

    CPC分类号： C12N5/0612 ,  A01K67/027 ,  A61D19/02 ,  C12N15/873 ,  G01N2015/149

    摘要： Artificial Insemination is achieved for sexed mammalian offspring in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be practical for commercial implementation. Improved insemination systems particularly adapted to use for sex-selected sperm sorting include systems which achieve superovulation and then multiple embryo production with sexed embryos. These systems combine with other techniques, including techniques for enhanced sheath fluid (3) and other strategies which minimize stress on the sperm cells (18), and potentially, a 2.9 percent sodium citrate sheath solution for bovine species and a hepes bovine gamete media for equine species. Improved collection systems (14) and techniques for the process are describeb so that commercial application of sperm samples as well as the resulting animals may now be achieved in the field.

    A HETEROGENEOUS INSEMINATE SYSTEM
    10.
    发明公开
    A HETEROGENEOUS INSEMINATE SYSTEM 有权
    系统FUR异构体BESAMUNG

    公开(公告)号：EP2579792A1

    公开(公告)日：2013-04-17

    申请号：EP11792787.1

    申请日：2011-06-08

    申请人： XY, LLC

    发明人： MORENO, Juan, F. ,  ROSENSTEIN, Maurice, A.

    IPC分类号： A61B17/43 ,  A61K38/00

    CPC分类号： A61D19/02 ,  A61B17/43 ,  A61D19/00 ,  C12N5/061

    摘要： A first amount of sperm of a first animal and a second amount of sperm of a second animal of the same species, the first amount of sperm and the second amount of sperm sex- selected sperm of the same sex, useful in the in-vivo or in-vitro fertilization of an egg of a female animal of the same species of animal for the production of sex-selected embryos and sex- selected offspring.

    摘要翻译： 第一种量的第一种动物的精子和第二种量的第二种动物的同一物种的精子，第一量的精子和第二量的精子性别选择的同一性别的精子，在体内有用 或同一种动物的雌性动物的卵的体外受精，用于产生性别选择的胚胎和性别选择的后代。