NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF
    8.
    发明公开
    NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF 审中-公开
    新型OMEGA-3和OMEGA-6脂肪酸组合物及其用途

    公开(公告)号:EP2627326A2

    公开(公告)日:2013-08-21

    申请号:EP11776135.3

    申请日:2011-10-12

    申请人: Vifor SA

    摘要: The present application relates to compositions for use in a method of treating and/or preventing mental and behavioral disorders and/or improving mental health and cognitive functions in a subject, comprising: a) Docosahexaenoic acid (DHA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; b) Eicosapentaenoic acid (EPA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; c) γ-linolenic acid (GLA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; and at least a psychostimulant compound selected among methylphenidate HCI, atomoxetine, amphetamine, gamma-hydroxybutyrate, dextroamphetamine, sibutramine, methylenedioxymethamphetamine, and/or an anxiolytic compound selected among fluoxatine, sertraline, paroxetine, fluoroxamine, citralopram, venlafaxine, bupropion, nefazodone, and mirtazapine. The present application also relates to the method of treating and/or preventing mental and behavioral disorders and/or improving mental health and cognitive functions in a subject, comprising administering an effective amount of a composition comprising: a) Docosahexaenoic acid (DHA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; b) Eicosapentaenoic acid (EPA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; c) γ-linolenic acid (GLA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; and at least a psychostimulant compound selected among methylphenidate HCI, atomoxetine, amphetamine, gamma-hydroxybutyrate, dextroamphetamine, sibutramine, methylenedioxymethamphetamine, and/or an anxiolytic compound selected among fluoxatine, sertraline, paroxetine, fluoroxamine, citralopram, venlafaxine, bupropion, nefazodone, and mirtazapine.

    摘要翻译: 本申请涉及用于在对象中治疗和/或预防精神和行为障碍和/或改善精神健康和认知功能的方法中的组合物,其包含:a)二十二碳六烯酸(DHA)和/或其药学上可接受的衍生物 和/或其前体; b)二十碳五烯酸(EPA)和/或其药学上可接受的衍生物和/或前体; c)γ-亚麻酸(GLA)和/或其药学上可接受的衍生物和/或前体; 和至少一种选自盐酸哌甲酯,阿托西汀,苯丙胺,γ-羟基丁酸酯,右旋安非他命,西布曲明,亚甲基二氧基甲基苯丙胺和/或选自氟西汀,舍曲林,帕罗西汀,氟胺,柠檬醛,文拉法辛,安非他酮,奈法唑酮和抗焦虑药的抗焦虑化合物中的精神兴奋剂化合物 米氮平。 本申请还涉及治疗和/或预防个体的精神和行为障碍和/或改善精神健康和认知功能的方法,其包括给予有效量的组合物,所述组合物包含:a)二十二碳六烯酸(DHA)和/ 或其药学上可接受的衍生物和/或前体; b)二十碳五烯酸(EPA)和/或其药学上可接受的衍生物和/或前体; c)γ-亚麻酸(GLA)和/或其药学上可接受的衍生物和/或前体; 和至少一种选自盐酸哌甲酯,阿托西汀,苯丙胺,γ-羟基丁酸酯,右旋安非他命,西布曲明,亚甲基二氧基甲基苯丙胺和/或选自氟西汀,舍曲林,帕罗西汀,氟胺,柠檬醛,文拉法辛,安非他酮,奈法唑酮和抗焦虑药的抗焦虑化合物中的精神兴奋剂化合物 米氮平。