Abstract:
A method for making composite PMC polymeric materials, based on TFE polymers and/or copolymers, having a controlled porosity and modularly adjustable properties, said method comprising the steps of: a) mixing a TFE polymer or copolymer with one or more organic, inorganic substances in a solid or liquid form, to adjust the chemical, physical and mechanical properties of the composite material; b) adding to the mixture chemical organic and inorganic composites and complex mixtures thereof, said substances being adapted to sublimate or quickly evaporate or transform into a gas by a thermal processing in a temperature range from 30° to 380°C, B Composites, said "B Composites" being absent in the end product after sintering; c) processing said mixture to form articles; d) thermally processing, under vacuum, said articles to form a controlled porosity; and e) thermally sintering said controlled porosity articles of said step d).
Abstract:
The present invention is a method of producing porous beads, which comprises the steps of providing a first liquid phase comprising a bead matrix material and essentially edgy templating particle(s), said particle(s) being treated with a surface modifying agent; providing a second liquid phase which is immiscible with the first liquid phase; contacting the first phase and the second phase under conditions resulting in an emulsion of droplets comprised of the first liquid phase dispersed in the continuous second liquid phase; transforming the droplets to mesoporous beads by solidification of the liquid; and removing the templating particle(s) from the beads without causing any essential change of the surrounding bead, whereby hierarchical networks of pores are provided in the beads.
Abstract:
The present invention relates to a method for fabricating a three-dimensional porous fibrous microstructure, various three-dimensional porous fibrous microstructures fabricated by the method, an apparatus for detecting a biological marker and a drug delivery system comprising the microstructure. The porous fibrous microstructure of the present invention has excellent interconnectivity between pores and micropores and captures and delivers target particles at high efficiency, and thus can be usefully applied to biomedical applications including the detection of a biomarker and drug delivery.
Abstract:
The present invention is a method of producing porous beads, which comprises the steps of providing a first liquid phase comprising a bead matrix material and essentially edgy templating particle(s), said particle(s) being treated with a surface modifying agent; providing a second liquid phase which is immiscible with the first liquid phase; contacting the first phase and the second phase under conditions resulting in an emulsion of droplets comprised of the first liquid phase dispersed in the continuous second liquid phase; transforming the droplets to mesoporous beads by solidification of the liquid; and removing the templating particle(s) from the beads without causing any essential change of the surrounding bead, whereby hierarchical networks of pores are provided in the beads.
Abstract:
The invention provides microporous foam suitable for medical applications and methods for preparing these foams. The microporous foams are of controlled pore size that may be utilized in a variety of applications. In general, the foams are characterized in that the pores are continuous and open-celled. In preparing the foams, an organic polymer is melted and combined with a selected solid crystalline fugitive compound, that melts above about 25 °C, and/or that sublimates at above about 25 °C or can be extracted, to produce a substantially isotropic solution. The solution is cooled under controlled conditions to produce a foam precursor containing the solidified fugitive composition dispersed through a matrix of the organic polymer. Crystals of fugitive composition are then removed by solvent extraction and/or sublimation, or like process to produce microcellular foams having a continuous, open-cell structure. The technique may also be utilized to produce filamentous foams, hollow fiber, catheters, and tubes by extrusion, sheets by casting and can also be applied for the creation of foamy or microtextured sufaces on solid polymeric substrates or microtextured organic polymeric surfaces.
Abstract:
The present invention relates to a method of preparing porous macroreticular polymers comprising polymerizing one or more monoethylenically unsaturated monomers in the presence of a silicone based porogen.
Abstract:
The present invention relates to a method of removing water insoluble porogens from macroreticular copolymers comprising distilling said porogen in water soluble organic solvent.