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    INFLUENZA C VIRUS AND VACCINE
    1.
    发明公开
    INFLUENZA C VIRUS AND VACCINE 审中-公开
    INFLUENZA-C-VIRUS UND IMPFSTOFFE

    公开(公告)号：EP2807184A1

    公开(公告)日：2014-12-03

    申请号：EP13704305.5

    申请日：2013-01-28

    申请人： Newport Laboratories, Inc.

    发明人： SIMONSON, Randy, R. ,  COLLIN, Emily, A. ,  HAUSE, Benjamin, M.

    IPC分类号： C07K14/11 ,  A61P31/16 ,  A61K39/145

    CPC分类号： C07K14/005 ,  A61K2039/5252 ,  C12N7/00 ,  C12N2760/16321 ,  C12N2760/16322 ,  C12N2760/16334

    摘要： A further influenza C virus with only low homology to any influenza C virus previously characterized. Challenge studies show that the virus can infect pigs and be transmitted between pigs. Additionally, influenza C is commonly thought of as a human pathogen and serological studies have been performed, looking at the incidence of antibodies against this virus in both pigs and humans. Approximately 10% of pigs and 30% of humans have antibodies to this virus. Additional experimental data show that the virus can infect and transmit in ferrets (a surrogate for human infection studies). In a third aspect, the present invention is the partial genome of this novel influenza C virus. In another aspect, the present invention is a method of detection in animals of this further influenza C virus.

    摘要翻译： 一种与以前特有的任何甲型流感病毒只有低同源性的新型甲型流感病毒。 挑战研究表明，病毒可以感染猪，并在猪之间传播。 此外，流感C通常被认为是人类病原体，并且已经进行了血清学研究，研究了猪和人中针对该病毒的抗体的发生率。 大约10％的猪和30％的人对这种病毒有抗体。 额外的实验数据表明病毒可以感染和传播在雪貂（人类感染研究的替代品）。 在第三方面，本发明是该新型流感C病毒的部分基因组。 另一方面，本发明是这种新型甲型流感病毒的动物检测方法。