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公开(公告)号:EP4105325B1
公开(公告)日:2024-10-02
申请号:EP21823718.8
申请日:2021-07-12
CPC分类号: C12N15/77 , C12N9/1077 , C12P19/32 , C12Y204/02007 , C12R2001/1520210501
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公开(公告)号:EP4405376A1
公开(公告)日:2024-07-31
申请号:EP22783442.1
申请日:2022-09-09
CPC分类号: C07K14/34 , C12P13/08 , C12R2001/1520210501
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公开(公告)号:EP4407038A1
公开(公告)日:2024-07-31
申请号:EP22872052.0
申请日:2022-09-22
发明人: MA, Yanhe , CAI, Tao , SUN, Hongbing , WANG, Qinhong , WANG, Guokun , XU, Zhaoyu , ZHU, Zhiguang , MA, Chunling , ZHENG, Ping , WANG, Yu , QIAO, Jing , DONG, Hongjun , GUO, Wei , ZHOU, Hongyi
CPC分类号: Y02P20/133 , C12R2001/0120210501 , C12R2001/1520210501 , C12N1/38 , C12N15/80 , C12R2001/1920210501 , C12N9/10 , C12N15/81 , C12N15/70 , C12R2001/64520210501 , C12P19/04 , C12N1/32 , C12N15/74 , C12N15/77 , C12N15/113 , C12P19/18 , C12R2001/8420210501
摘要: Provided are a method for preparing starch using carbon dioxide, a recombinant microorganism, a method for constructing the recombinant microorganism, and a reagent. The method for preparing starch using carbon dioxide comprises: (1) providing energy and carbon sources for microbial cells on the basis of carbon dioxide and extracellular non-optical energy; and (2) generating starch within the microbial cells on the basis of at least one of up-regulated glucose-1-phosphate adenylyltransferase and starch synthase in the microbial cells. In this way, by utilizing non-optical energy, such as electric energy or hydrogen energy, starch can be effectively prepared inside the microbial cells by fixing carbon dioxide.
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公开(公告)号:EP4050101B1
公开(公告)日:2024-06-26
申请号:EP21739220.8
申请日:2021-04-22
CPC分类号: C12N9/1085 , C12N1/205 , C12R2001/1520210501 , C12P19/32 , C12Y205/01032
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5.
公开(公告)号:EP4353827A3
公开(公告)日:2024-06-19
申请号:EP23216023.4
申请日:2021-06-29
发明人: CHOI, Min Jin , KIM, Bong Ki , KIM, Ha Eun , PARK, Seok Hyun , PARK, Joon Hyun
CPC分类号: C12N9/93 , C12P13/08 , C12N15/77 , C12R2001/1520210501 , C12Y604/01001
摘要: The present disclosure relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The mutant strain may produce L-lysine in an improved yield due to increased or enhanced expression of the gene encoding pyruvate carboxylase, compared to a parent strain thereof.
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公开(公告)号:EP4424299A1
公开(公告)日:2024-09-04
申请号:EP22887627.2
申请日:2022-10-26
申请人: CJ Bioscience, Inc.
发明人: SHIN, Changsik , LEE, Ji Young , KWON, Bo Eun , KIM, Hyun Jeong , KIM, Hanseol , PARK, Hyunkyung , CHOI, Joung Eun
CPC分类号: A61Q19/00 , C12R2001/1520210501 , A61K8/99 , C12N1/20
摘要: The present application relates to a use of a strain of the genus Cutibacterium, a culture of the strain, or a combination thereof for prevention, amelioration, and/or treatment of inflammatory skin diseases. A composition comprising a strain of the genus Cutibacterium, a culture of the strain, or a combination thereof does not show cytotoxicity, inhibits proliferation of immune cells that cause skin inflammation, suppresses immune responses, has an antibacterial effect against acne-causing bacteria, and promotes regeneration of skin cells, thereby exhibiting excellent preventive, ameliorating, and/or therapeutic effects of inflammatory skin diseases.
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8.
公开(公告)号:EP4384624A1
公开(公告)日:2024-06-19
申请号:EP22873184.0
申请日:2022-09-22
发明人: KWON, Nara , BONG, Hyun-Ju , LEE, Ah Reum , HEO, Jung Ok
CPC分类号: C12N15/77 , C07K14/34 , C12P13/18 , C12P13/14 , C12R2001/1520210501
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公开(公告)号:EP4384538A1
公开(公告)日:2024-06-19
申请号:EP22760742.1
申请日:2022-08-03
IPC分类号: C07K14/315 , C12P21/02
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公开(公告)号:EP4361268A1
公开(公告)日:2024-05-01
申请号:EP22819356.1
申请日:2022-05-24
发明人: ZHENG, Ping , LIU, Jiao , SUN, Jibin , SUN, Guannan , ZHOU, Wenjuan , GUO, Xuan
IPC分类号: C12N15/113 , C12N15/09 , C12N1/20 , C07K14/34 , C12N15/67 , C12R1/15 , C12R1/185 , C12R1/13 , C12R1/06
CPC分类号: C12N15/77 , C12N15/67 , C12N15/113 , C12R2001/1520210501 , C12R2001/1920210501 , C12N15/70 , C12N15/74 , C12R2001/18520210501 , C07K14/34 , C12R2001/1320210501 , C12N15/09 , C12R2001/0620210501 , C12N1/20
摘要: A polynucleotide having promoter activity of a malate dehydrogenase gene (mdh gene), a transcription expression cassette, recombinant expression vector and recombinant host cell containing the polynucleotide having the promoter activity, a method for constructing a promoter mutant, a method for regulating the transcription of a target gene, a method for preparing a protein, and method for producing a target compound. The polynucleotide having the promoter activity is a mutant of an mdh gene promoter, and compared with a promoter of a wild-type mdh gene, the promoter activity of the mutant is significantly improved. After operably linking the mutant to a target gene, the expression efficiency of the target gene can be significantly improved, thereby effectively improving the yield and transformation rate of a target compound.
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