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23 条记录 (耗时 0.012 秒)

    METHOD TO DETECT BACTERIA
    3.
    发明授权
    METHOD TO DETECT BACTERIA 失效
    方法细菌检测

    公开(公告)号：EP0876504B1

    公开(公告)日：2002-10-30

    申请号：EP96942457.1

    申请日：1996-12-16

    申请人： Biotec Laboratories Limited

    发明人： WILSON, Stuart, Mark

    IPC分类号： C12Q1/04 ,  C12Q1/06 ,  C12Q1/10 ,  C12N15/03

    CPC分类号： C12Q1/06 ,  C12Q1/04 ,  C12Q1/10 ,  G01N2333/35 ,  Y10S435/864 ,  Y10S435/866

    摘要： The present invention relates to a method for enhancing the time of response of an assay for a first bacterium, characterised in that: a) the said first bacterium is exposed to infection by phage particles to which the said first bacterium is permissive; b) the infected bacterium is treated to in-activate exogenous phage particles; c) the treated bacterium is cultivated in the presence of a second bacterium which is permissive to said phage or its replicand and which has a doubling rate greater than the effective doubling rate of the first bacterium; and d) assessing the extent of plaque formation and/or of second bacterium growth in the cultivated second bacterium cells. The method of the invention can be used to assess the presence of first bacterium in a sample, notably where the first bacterium is a slow growing bacterium, especially Mycobacterium tuberculosis, where the method of the invention enables an operator to detect the presence of low amounts of the bacterium in a sample within days instead of the weeks required with conventional bacterial cultivation techniques. The invention can also be used to assess the effect of a drug or other treatment on a bacterium or of a virus. The invention also provides a diagnostic kit for use in the method of the invention.

    METHOD AND APPARATUS FOR SPECIATING AND IDENTIFYING MAI (MYCOBACTERIUM AVIUM-INTRACELLULARE)
    10.
    发明授权
    METHOD AND APPARATUS FOR SPECIATING AND IDENTIFYING MAI (MYCOBACTERIUM AVIUM-INTRACELLULARE) 失效
    方法和装置种固定及标识可（鸟分枝杆菌胞内）

    公开(公告)号：EP0497876B1

    公开(公告)日：1996-08-28

    申请号：EP90916606.8

    申请日：1990-10-16

    申请人： INFECTECH, INC.

    发明人： OLLAR, Robert, A.

    IPC分类号： C12Q1/04 ,  C12Q1/18 ,  G01N33/569

    CPC分类号： C12Q1/18 ,  C12Q1/04 ,  G01N33/5695 ,  G01N2333/35 ,  Y10S435/863 ,  Y10S435/864 ,  Y10S435/975

    摘要： A method of speciating and identifying MAI in a specimen comprises placing a paraffin coated slide in a receptacle containing a sterile aqueous solution inoculated with the specimen, analyzing the slide after exposure to the specimen to determine the presence or absence of atypical Mycobacteria, and after the analysis step, if atypical Mycobacteria are determined to be present, performing at least one speciation assay to ascertain if the atypical Mycobacteria are MAI. A related apparatus is also disclosed for speciating and identifying MAI in a specimen comprising a paraffin-wax coated slide, a tube having a sterile aqueous solution contained therein, the tube adapted to hold the slide, and at least one speciation assay means for performing an assay to determine the presence or absence of MAI in the speciment after the speciment is introduced into the tube holding the solution and the slide. An apparatus and method for determining the sensitivity of MAI to different antibiotics and dosages thereof is also provided.