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233 条记录 (耗时 0.019 秒)

    SYNERGISTISCHE WIRKSTOFFKOMBINATIONEN ZUR KOSMETISCHEN ODER DERMATOLOGISCHEN PFLEGE DER HAUT ODER DER HAUTANHANGSGEBILDE
    1.
    发明授权
    SYNERGISTISCHE WIRKSTOFFKOMBINATIONEN ZUR KOSMETISCHEN ODER DERMATOLOGISCHEN PFLEGE DER HAUT ODER DER HAUTANHANGSGEBILDE 失效
    协同ACTIVE组合化妆品或皮肤护理皮肤或皮肤相关的结构

    公开(公告)号：EP0674505B2

    公开(公告)日：2009-08-12

    申请号：EP94900762.9

    申请日：1993-12-07

    申请人： Beiersdorf Aktiengesellschaft

    发明人： SAUERMANN, Gerhard ,  SCHÖNROCK, Uwe ,  SCHREINER, Volker ,  STÄB, Franz

    IPC分类号： A61K31/415 ,  A61K8/35 ,  A61K8/365 ,  A61K8/49 ,  A61K8/67 ,  A61Q19/00 ,  A61Q19/08

    CPC分类号： A61K8/67 ,  A61K8/365 ,  A61K2800/59 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08 ,  Y10S514/861 ,  Y10S514/864 ,  Y10S514/88 ,  Y10S514/881

    摘要： The invention concerns cosmetic and/or dermatological combinations of active substances consisting of (a) an active amount of biotin and/or biotin esters, (b) an active amount of one or more α-hydroxycarboxylic acids of general formula (I) and/or an effective amount of one or more α-ketocarboxylic acids of the formula (II) in which R' and R', independently of each other, are selected from the group comprising (b1) H, (b2) branched-chain or straight-chain C1-25 alkyl, (b3) branched-chain or straight-chain C1-25 alkyl substituted with one or more carboxyl groups and/or hydroxy groups and/or aldehyde groups and/or oxo groups (keto groups), (b4) phenyl, (b5) phenyl substituted with one or more carboxyl groups and/or hydroxy groups and/or branched-chain and/or straight-chain C1-25 alkyl groups, or in which the α-carbon atom of the α-hydroxy-carboxylic acid forms, together with R' and R', (b6) an unsubstituted cycloalkyl group with 3 to 7 ring atoms or (b7) a cycloakyl group with 3 to 7 ring atoms, substituted with one or more carboxylic groups and/or hydroxy groups and/or oxo groups (keto groups) and/or straight-chain and/or branched-chain C1-25 alkyl groups, whereby the α-hydroxycarboxylic acid or acids or the α-ketocarboxylic acid or acids may be present as their physiologically tolerated salts and/or ethyl esters and/or methyl esters and (c) optionally an active amount of one or more antioxidants. The invention also concerns preparations containing such combinations of active substances.

    External preparations for treating dermatoses
    8.
    发明公开
    External preparations for treating dermatoses 失效
    PräparatezuräusserlichenAnwendung zur Behandlung von Dermatosen

    公开(公告)号：EP1374861A1

    公开(公告)日：2004-01-02

    申请号：EP03015859.6

    申请日：1996-04-22

    申请人： SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA

    发明人： Shimizu, Tatsuo ,  Horiguchi, Tomoko ,  Kuriyama, Kiyoshi ,  Watabe, Mitsuo

    IPC分类号： A61K31/01 ,  A61K31/355 ,  A61K47/16 ,  A61K47/14 ,  A61K47/12 ,  A61K9/06 ,  A61K9/70

    CPC分类号： A61K31/01 ,  A61K31/355 ,  A61K31/575 ,  A61K45/06 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/864 ,  A61K2300/00

    摘要： The first invention provides an external preparation for treating dermatoses comprising vitamin E and squalane, which has an efficacy at least equivalent to that of external preparations containing adrenocortical hormones as the active ingredient. The second invention provides an external preparation for treating dermatoses comprising an adrenocortical hormone, vitamin E and squalane, which is reduced in adrenocortical hormone content as compared with conventional preparations, is also reduced in side effects, and has high clinical efficacy. The third invention provides an external preparation for treating dermatoses comprising a nonsteroidal antiinflammatory agent, vitamin E and squalane and/or squalene, which is reduced in side effects and is highly efficacious. The fourth invention provides an external preparation for treating dermatoses comprising an antihistaminic agent, vitamin E and squalane and/or squalene, which is reduced in side effects and is highly efficacious like the above preparation. The fifth invention provides an external preparation for treating dermatoses comprising vitamin E, squalene and squalane, which is reduced in side effects and is highly efficacious.

    摘要翻译： 第一项发明提供了用于治疗包含维生素E和角鲨烷的皮肤病的外用制剂，其具有至少相当于含有肾上腺皮质激素作为活性成分的外用制剂的功效。 第二发明提供了用于治疗皮肤病的外用制剂，其包含与常规制剂相比降低肾上腺皮质激素含量的肾上腺皮质激素，维生素E和角鲨烷，还减少副作用，并具有高临床疗效。 第三发明提供了用于治疗皮肤病的外用制剂，其包含非甾体抗炎剂，维生素E和角鲨烷和/或角鲨烯，其降低副作用并且是高度有效的。 第四发明提供了用于治疗皮肤病的外用制剂，其包含抗组胺剂，维生素E和角鲨烷和/或角鲨烯，其降低了副作用，并且与上述制剂一样是高效的。 第五发明提供了用于治疗皮肤病的外用制剂，其包含维生素E，角鲨烯和角鲨烷，其减少副作用并且是高度有效的。