公开(公告)号：EP3204794B1

公开(公告)日：2023-12-27

申请号：EP15848657.1

申请日：2015-10-08

发明人： RAVI, Ananth ,  EASTON, Harry

IPC分类号： G01T1/08 ,  A61B1/31 ,  A61N5/00 ,  G01T1/10

公开(公告)号：EP3401705A1

公开(公告)日：2018-11-14

申请号：EP16883828.2

申请日：2016-12-26

申请人： Tokuyama Corporation

发明人： YANAGIDA Takayuki ,  OKADA Go ,  FUKUDA Kentaro ,  MATSUO Kentaro ,  KATO Takumi

IPC分类号： G01T1/10 ,  C09K11/00 ,  C09K11/55

CPC分类号： C09K11/00 ,  C09K11/55 ,  G01T1/10

摘要： The object of the present invention is to provide a dosimeter capable of reading out a dose multiple times and excellent in biological tissue equivalence, and a radiation measuring method using this dosimeter. A dosimeter of the present invention comprises a detecting element containing magnesium oxide and a dose measuring system thereof is a radio-photoluminescence system. The detecting element preferably comprises a single-crystal body or a sintered body of magnesium oxide, and more preferably further contains a rare-earth element such as samarium. Moreover, the radiation measuring method of the present invention uses the dosimeter of the present invention and a dose measuring system thereof is a radio-photoluminescence system.

公开(公告)号：EP3062880A4

公开(公告)日：2017-11-29

申请号：EP14866277

申请日：2014-11-26

申请人： DALHOUSIE UNIV

发明人： ROBAR JAMES ,  SU SHIQIN

IPC分类号： A61N5/10 ,  A61B6/00 ,  B29C67/04 ,  B33Y50/02 ,  G01T1/10 ,  G01T1/20

CPC分类号： A61N5/1031 ,  A61B6/032 ,  A61B6/5217 ,  A61N5/1048 ,  A61N5/1075 ,  A61N2005/1034 ,  A61N2005/1076 ,  A61N2005/1087 ,  A61N2005/1089 ,  A61N2005/1096 ,  A61N2005/1097 ,  B29C64/106 ,  B29C64/386 ,  B29K2067/046 ,  B29K2995/0056 ,  B29L2031/753 ,  B33Y50/02 ,  B33Y80/00

摘要： Disclosed herein are systems, methods, and computer-readable storage devices for manufacturing patient-specific bolus for use in targeted radiotherapy treatment. Based on dose calculations without a bolus and based on three-dimensional scan data of a patient, the example system generates a model of a bolus for targeting radiotherapy treatment to a planning target volume or target region within the patient. The system can perform several iterations to generate a resulting model for the bolus. Then, the system can generate instructions for controlling a three-dimensional printer to generate the bolus that conforms to the patient's skin surface while also specifically targeting the planning target volume for the radiotherapy treatment. In this way, the amount of radiotherapy treatment administered to other tissue is reduced, while the costs, time, and human involvement in creating the bolus are significantly reduced.

公开(公告)号：EP2567257A4

公开(公告)日：2015-07-08

申请号：EP11778432

申请日：2011-05-06

申请人： IMMUNOLIGHT LLC ,  UNIV DUKE

发明人： FATHI ZAKARAYAE ,  CLAYTON JAMES ,  WALDER HAROLD ,  BOURKE FREDERIC A JR ,  STANTON IAN ,  AYRES JENNIFER ,  STECHER JOSHUA T ,  THERIEN MICHAEL ,  TOONE ERIC ,  GOODEN DAVE ,  DEWHIRST MARK ,  HERBERT JOSEPH A ,  FELS DIANE ,  HANSEN KATHERINE S

IPC分类号： G01T1/10 ,  C08K3/00 ,  C09J4/00 ,  G01N21/64 ,  G21G5/00

CPC分类号： H01L24/83 ,  A61B17/0057 ,  A61L24/06 ,  B32B3/266 ,  B32B7/14 ,  B32B9/04 ,  B32B37/1284 ,  B32B37/18 ,  B32B38/0008 ,  B32B2037/1253 ,  B32B2457/00 ,  B32B2457/08 ,  B32B2457/14 ,  B41J2/17559 ,  C08K3/00 ,  C09J4/00 ,  C09J9/02 ,  C09J11/04 ,  C09J11/06 ,  C09J133/08 ,  C09K11/02 ,  C09K11/7769 ,  C09K11/777 ,  H01L23/5226 ,  H01L24/32 ,  H01L25/0657 ,  H01L25/50 ,  H01L2224/16225 ,  H01L2224/32225 ,  H01L2224/48091 ,  H01L2224/48227 ,  H01L2224/73204 ,  H01L2224/73253 ,  H01L2224/73265 ,  H01L2224/83192 ,  H01L2224/83855 ,  H01L2224/92125 ,  H01L2225/06524 ,  H01L2225/06589 ,  H01L2924/07811 ,  H01L2924/1461 ,  H01L2924/15311 ,  Y10T428/2852 ,  H01L2924/00014 ,  H01L2924/00

摘要： A polymerizable composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and a phosphor capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.

公开(公告)号：EP2864812A2

公开(公告)日：2015-04-29

申请号：EP13807537.9

申请日：2013-06-21

申请人： LANDAUER, INC.

发明人： AKSELROD, Mark ,  YODER, R. Craig

IPC分类号： G01T1/10

CPC分类号： G01T1/10 ,  G01T1/105

摘要： The invention resides in an apparatus comprising an LED light source (134) for emitting a green illumination light (132) for illuminating an optically stimulated luminescence (OSL) sensor, a photodetector (162) for detecting of green luminescent light emitted by the OSL sensor, a pulse counter for counting photon pulses generated by a photodetector based on photons of luminescent light emitted by the OSL sensor and counted by the photodetector, and a microprocessor (166) for controlling the LED light source and the photodetector and the pulse counter. The microprocessor controls when the LED light source, the photodetector and the pulse counter are switched between an on state and an off state. The pulse counter is part of the microprocessor, and the microprocessor determines a radiation dose of one type of ionizing radiation to which the OSL sensor has been exposed based on the photon pulses counted by the pulse counter.

公开(公告)号：EP2857862A2

公开(公告)日：2015-04-08

申请号：EP14200642.8

申请日：2011-04-08

申请人： Landauer, Inc.

发明人： Yoder, Craig ,  Akselrod, Mark ,  Dillin, Kent ,  Fomenko, Vasiliy ,  Johnson, David

IPC分类号： G01T1/10 ,  G01T7/00

CPC分类号： G01T1/105 ,  G01T1/10 ,  G01T1/115

摘要： Described is a portable dosimeter reader that is small in size and light in weight

摘要翻译： 描述的是便携式剂量计读取器，其尺寸小并且重量轻

公开(公告)号：EP2701194A2

公开(公告)日：2014-02-26

申请号：EP13194084.3

申请日：2005-06-07

申请人： Fluidigm Corporation

发明人： Unger, Marc, A ,  Facer, Geoffrey, Richard ,  Clerkson, Barry ,  Cesar, Christopher, G ,  Switz, Neil

IPC分类号： H01L27/00 ,  G01T1/10 ,  G01N21/00 ,  G01N21/64 ,  H05B33/00 ,  G01J3/30 ,  C12Q1/00

CPC分类号： C12Q1/686 ,  B01J2219/00576 ,  B01J2219/00704 ,  B01L3/5027 ,  B01L7/52 ,  G01N21/64 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/75 ,  G01N21/8483 ,  G01N27/44721 ,  G01N2021/6421 ,  G01N2201/061 ,  G02B21/16 ,  G02B21/36

摘要： An apparatus for imaging one or more selected fluorescence indications from a microfluidic device (205). The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device (205). The imaging path provides for transmission of one or more fluorescent emission signals derived from one or more samples in the at least one chamber of the at least one microfluidic device (205). The chamber has a chamber size, the chamber size being characterized by an actual spatial dimension normal to the imaging path. The apparatus also includes an optical lens system (210, 212) coupled to the imaging path. The optical lens system is adapted to transmit the one or more fluorescent signals associated with the chamber.

摘要翻译： 一种用于从微流体装置（205）成像一个或多个选定的荧光指示的装置。 该装置包括耦合到至少一个微流体装置（205）中的至少一个室的成像路径。 成像路径提供从至少一个微流体装置（205）的至少一个室中的一个或多个样品衍生的一个或多个荧光发射信号的传输。 腔室具有腔室尺寸，腔室尺寸的特征在于与成像路径垂直的实际空间尺寸。 该装置还包括耦合到成像路径的光学透镜系统（210,212）。 光学透镜系统适于透射与腔室相关联的一个或多个荧光信号。

公开(公告)号：EP2671096A2

公开(公告)日：2013-12-11

申请号：EP12706651.2

申请日：2012-01-30

申请人： Commissariat à l'Énergie Atomique et aux Énergies Alternatives

发明人： NEGRE, Jean-Paul

IPC分类号： G01T1/10

CPC分类号： G01T1/10 ,  G01T1/105

摘要： Sensitive charge for passive dosimeter includes a plurality of flexible photostimulable screens designed to be stacked inside a dosimeter casing and each having a radiosensitive layer of radiophotoluminescent material which can therefore be read differentially by illumination. The screens being integral with a foldable support having two configurations, namely a folded detection configuration, in which the screens are stacked on one another, and an unfolded reading configuration, in which the screens are arranged alongside one another on the same face of the support. Intercalated sheets with reinforcing/absorbing effect can also be fixed to the support, alternating with the screens, the screens being separated from the adjacent screens by two folds and the sheets are separated from the adjacent sheets by two folds.

公开(公告)号：EP2442139A2

公开(公告)日：2012-04-18

申请号：EP11182064.3

申请日：2009-10-22

申请人： Landauer, Inc.

发明人： Akselrod, Mark S. ,  Sykora, Garret J.

IPC分类号： G01T1/02 ,  G01T1/10

CPC分类号： G01T1/10 ,  G01T5/00

摘要： A method of determining the doses of neutrons, gamma and X-ray photons, beta, alpha and other ionizing radiations using a method of image processing in spatial and frequency domain that produces parameters that are related to the radiation dose absorbed in a luminescent material. Portions of the luminescent material may be covered by different converters to allow for doses of different radiations to be discriminated.

摘要翻译： 一种使用空间和频率域图像处理方法确定中子，γ和X射线光子，β，α和其他电离辐射剂量的方法，该方法产生与在发光材料中吸收的辐射剂量有关的参数。 发光材料的部分可以被不同的转换器覆盖以允许区分不同辐射的剂量。

公开(公告)号：EP2413161A2

公开(公告)日：2012-02-01

申请号：EP11182063.5

申请日：2009-10-22

申请人： Landauer, Inc.

发明人： Akselrod, Mark S. ,  Sykora, Garret, J.

IPC分类号： G01T1/10

CPC分类号： G01T1/10 ,  G01T5/00

摘要： A method of determining the doses of neutrons, gamma and X-ray photons, beta, alpha and other ionizing radiations using a method of image processing in spatial and frequency domain that produces parameters that are related to the radiation dose absorbed in a luminescent material. Portions of the luminescent material may be covered by different converters to allow for doses of different radiations to be discriminated.

摘要翻译： 使用在空间和频域中的图像处理方法来确定与发光材料中吸收的辐射剂量相关的参数的中子，γ和X射线光子，β，α和其他电离辐射的剂量的方法。 发光材料的一部分可以由不同的转换器覆盖，以允许区分不同辐射的剂量。