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公开(公告)号：EP4153558B1
公开(公告)日：2023-08-02
申请号：EP21724282.5
申请日：2021-05-07
IPC分类号： C07C67/297 , C07D311/32 , C07C49/84 , C07C69/18 , C07C45/69 , C07C45/65 , C07D311/74
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公开(公告)号：EP1753708B1
公开(公告)日：2018-02-21
申请号：EP05711939.8
申请日：2005-01-19
发明人： ANDRUS, Merritt, B. , LIU, Jing
IPC分类号： C07C67/08 , C07C67/14 , C07C67/287 , C07C67/29 , C07C67/293 , C07C69/017 , C07C69/16 , C07C69/18 , C07C69/63 , C07C69/716
CPC分类号： C07C69/017 , C07C67/08 , C07C67/14 , C07C67/287 , C07C67/29 , C07C67/293 , Y02P20/55 , C07C69/716 , C07C69/63 , C07C69/18 , C07C69/16
摘要： The present invention includes methods for preparing resveratrol, resveratrol esters and substituted and unsubstituted stilbenes of the formula given below; where each Y is —O or halogen, each Z is —O or halogen, each n and each m is independently the value of 0, 1, 2, 3, 4 or 5, each A and each B is independently selected from Pn, R or absent, each V and each W is independently selected from Pn, straight or branched alkyl of from 2 to 6 carbon atoms and cycloalkyl of from 3 to 8 carbon atoms, alkoxy, phenyl, benzyl or halogen, R is independently selected from the group comprising alkyl with at least one carbon atom, aryl and aralkyl, Pn is an alcohol protecting group and diastereoisomers of the foregoing. The compounds are made from a multi-step process including a N-heterocyclic carbene-type ligand coupling in the presence of a base with benzyol halide and styrene coupling partners. These compounds show increased stability for use in the food, cosmetic and pharmaceutical industries.
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3.发明公开BIO-POLYOLS FOR BIO-LUBRICANT AND BIO-POLYMER AND METHODS FOR THE PREPARATION THEREOF 审中-公开用于生物活性剂和生物聚合物的生物多元醇及其生产方法
公开(公告)号：EP2819990A4
公开(公告)日：2015-09-23
申请号：EP13755362
申请日：2013-02-28
IPC分类号： C07C67/31 , A61K31/047 , C07C69/18 , C11D3/10
CPC分类号： C07C67/02 , C07C51/09 , C07C67/00 , C07C67/03 , C07C67/08 , C07C67/39 , C11C1/005 , C11C1/04 , C11C3/00 , C11C3/003 , C11C3/006 , C11C3/02 , C07C69/48 , C07C69/24 , C07C69/30 , C07C69/33
摘要： A method for producing an ester polyol, comprising transesterifying a first ester polyol with a primary polyol to produce a second ester polyol, wherein the second ester polyol has a higher hydroxyl value than the first ester polyol.
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公开(公告)号：EP2714643A4
公开(公告)日：2015-04-29
申请号：EP12793877
申请日：2012-03-30
CPC分类号： A24B15/12 , A24B15/10 , A24B15/24 , A24B15/30 , A24B15/302 , C07C29/095 , C07C51/09 , C07C67/08 , C07C69/34 , C07C31/225 , C07C69/18 , C07C53/08
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5.发明公开TRIACYLGLYCEROL PURIFICATION BY A CONTINUOUS REGENERABLE ADSORBENT PROCESS 审中-公开TRIACYLGLYCEROLREINIGUNG通过连续处理与再生吸附
公开(公告)号：EP2361257A4
公开(公告)日：2012-07-25
申请号：EP09818118
申请日：2009-10-02
发明人： MUNSON JAMES R , COOKE BRIAN S , BERTRAM BRYAN L
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6.发明公开
公开(公告)号：EP2295394A1
公开(公告)日：2011-03-16
申请号：EP09170121.9
申请日：2009-09-11
IPC分类号： C07C29/92 , C07C67/03 , C07C67/08 , C07C67/54 , C07C69/14 , C07C69/24 , C07C69/18 , C07C69/30 , C07C31/22
摘要： The present invention generally concerns a process for the purification of crude glycerol obtained as a by-product of industrial processes such as saponification, hydrolysis and transesterification with low chain alcohols of natural oils and fats. The present invention particularly concerns the purification treatment of crude glycerol obtained as a by-product of the biodiesel production from vegetable oils and animal fats, aiming to obtain a concentrated purified product.
摘要翻译： 本发明一般涉及纯化作为工业过程的副产物获得的粗甘油的方法，例如皂化，水解和酯交换与天然油和脂肪的低链醇。 本发明特别涉及作为来自植物油和动物脂肪的生物柴油生产的副产物获得的粗甘油的纯化处理，旨在获得浓缩的纯化产物。
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公开(公告)号：EP1623704A4
公开(公告)日：2009-04-01
申请号：EP04730641
申请日：2004-04-30
申请人： TAKARA BIO INC
发明人： ENOKI TATSUJI , KOBAYASHI EIJI , OGAWA KINUKO , KUDO YOKO , TANABE MASASHIGE , SUGIYAMA KATSUMI , OHNOGI HIROMU , SAGAWA HIROAKI , KATO IKUNOSHIN
IPC分类号： A61K31/121 , A23K1/16 , A23L1/30 , A61K31/222 , A61K31/341 , A61K31/343 , A61K31/351 , A61K31/352 , A61K31/365 , A61K31/366 , A61K31/381 , A61P3/08 , A61P3/10 , A61P5/50 , A61P43/00 , C07C49/835 , C07C49/84 , C07C69/017 , C07C69/157 , C07C69/16 , C07C69/18 , C07D307/46 , C07D309/12 , C07D311/32 , C07D493/08
CPC分类号： A61K31/365 , A23K20/111 , A23K20/116 , A23L33/10 , A61K31/121 , A61K31/222 , A61K31/341 , A61K31/343 , A61K31/351 , A61K31/352 , A61K31/366 , A61K31/381 , C07C49/84 , C07C69/017 , C07D307/46
摘要： A preventive or therapeutic agent for diseases accompanied by insulin level or insulin response disorder, characterized in that at least one compound selected from the group consisting of chalcone compounds, acetophenone compounds, coumarin compounds, phthalide compounds, derivatives of these and pharmacologically acceptable salts thereof is contained as an active ingredient. There are further provided an insulin-like agent; a food, beverage or feed; a promoter of glucose introjection in cells; and an agent capable of inducing differentiation to lipocytes.
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公开(公告)号：EP1623704A1
公开(公告)日：2006-02-08
申请号：EP04730641.0
申请日：2004-04-30
申请人： TAKARA BIO INC.
发明人： ENOKI, Tatsuji , KOBAYASHI, Eiji , OGAWA, Kinuko , KUDO, Yoko , TANABE, Masashige , SUGIYAMA, Katsumi , OHNOGI, Hiromu , SAGAWA, Hiroaki , KATO, Ikunoshin
IPC分类号： A61K31/121 , A61K31/222 , A61K31/343 , A61K31/341 , A61K31/365 , A61K31/351 , A61K31/381 , A61K31/366 , A61K31/352 , A61P43/00 , A61P3/10 , A61P3/08 , A61P5/50 , C07D493/08 , C07D309/12 , C07D311/32 , C07C49/84 , C07C49/835 , C07C69/18 , C07C69/157 , C07C69/16
CPC分类号： A61K31/365 , A23K20/111 , A23K20/116 , A23L33/10 , A61K31/121 , A61K31/222 , A61K31/341 , A61K31/343 , A61K31/351 , A61K31/352 , A61K31/366 , A61K31/381 , C07C49/84 , C07C69/017 , C07D307/46
摘要： A therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of a chalcone compound, an acetophenone compound, a coumarin compound, a phthalide compound, derivatives thereof, and pharmacologically acceptable salts thereof.
摘要翻译： 用于伴随胰岛素或胰岛素反应量异常的疾病的治疗剂和预防剂，胰岛素模拟作用剂，食品，饮料和饲料，用于增强葡萄糖摄入细胞的药剂和药剂 用于诱导分化为脂肪细胞的方法，其特征在于，每种包含至少一种选自查耳酮化合物，苯乙酮化合物，香豆素化合物，苯酞化合物，其衍生物和其药理学上可接受的盐中的至少一种化合物作为有效成分 。
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公开(公告)号：EP0765862A1
公开(公告)日：1997-04-02
申请号：EP95921128.5
申请日：1995-06-07
申请人： Kao Corporation
IPC分类号： C07C69/18 , C07C69/21 , C07C69/30 , C07C69/33 , C07C67/29 , C07C43/10 , C07C43/15 , C07C41/20 , A61K7/08
CPC分类号： A61K8/375 , A61Q5/00 , A61Q19/00 , C07C43/10 , C07C43/135 , C07C67/26 , C07C69/18 , C07C69/21 , C07C69/30
摘要： The present invention relates to a fatty acid ester of an etherified polyhydric alcohol represented by the following general formula (1), a production process thereof, a cosmetic composition comprising this compound, and a production process of an etherified polyhydric alcohol via the ester.
G(A) x (B) y (1)
(G: a residue formed by removing H atoms of all the OH groups of a polyhydric alcohol having at least three OH groups, A: -CH 2 CH(OH)R or -CHRCH 2 OH, R 1 : R 1a or -CH 2 OR 1a (R 1a : C 1 -C 36 alkyl or alkenyl group), B: H or C 1 -C 11 acyl group, x + y: the number of the OH groups of G, x ≥ 1, y ≥ 1, and at least one of y groups B: acyl group).
The compound (1) is not only useful as an intermediate for the production of an etherified polyhydric alcohol, but also excellent per se in the performance as a cosmetic base, emulsifier, lubricant, oily component and the like.摘要翻译： 本发明涉及由下述通式（1）表示的醚化多元醇的脂肪酸酯，其制备方法，包含该化合物的化妆品组合物以及经由该酯的醚化多元醇的制备方法。 G（A）×（B）y（1）（G：通过除去具有至少三个OH基团的多元醇的全部OH基团，A：-CH 2 CH（OH）R或-CHRCH 2 OH而形成的残基， R1：R1a或-CH2OR1a（R1a：C1-C36烷基或烯基），B：H或C1-C11酰基，x + y：G的OH基数，x≥1，y≥1和 y组中的至少一个B：酰基）。 化合物（1）不仅作为制造醚化多元醇的中间体有用，而且作为化妆品基剂，乳化剂，润滑剂，油性成分等的性能本身也优异。
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