公开(公告)号：EP3665294B1

公开(公告)日：2024-10-23

申请号：EP18765177.3

申请日：2018-08-06

发明人： PERINI, Davide ,  PAGLINO, Alessandra ,  SCARDUA, Alessandro

IPC分类号： C12P7/44

公开(公告)号：EP3257934B1

公开(公告)日：2024-10-23

申请号：EP16748721.4

申请日：2016-02-04

发明人： TIAN, Chaoguang ,  LI, Jingen ,  LONG, Chuannan ,  SUN, Tao ,  LIN, Liangcai ,  XU, Jing ,  LIU, Qian ,  JI, Jingxiao ,  SUN, Wenliang ,  MA, Yanhe

IPC分类号： C12P7/44 ,  C12P7/46 ,  C12P7/50 ,  C12N15/80 ,  C12N9/00 ,  C12N9/04 ,  C12N9/10 ,  C07K14/37 ,  C12N1/15 ,  C12N15/52 ,  C12R1/645

公开(公告)号：EP4296364A3

公开(公告)日：2024-08-21

申请号：EP23208030.9

申请日：2014-11-25

申请人： Genomatica, Inc.

发明人： Osterhout, Robin E. ,  Burgard, Anthony P. ,  Pharkya, Priti ,  Andrae, Stefan

IPC分类号： C12N1/19 ,  C12N1/15 ,  C12N1/13 ,  C12N1/11 ,  C12N15/70 ,  C12N15/81 ,  C12P7/42 ,  C12P5/02 ,  C12P13/00 ,  C12P17/10 ,  C12N1/14 ,  C12N1/20 ,  C12P7/02 ,  C12P7/40 ,  C12P7/04 ,  C12P7/44 ,  C12P7/18

CPC分类号： C12N1/14 ,  C12N1/20 ,  C12P7/02 ,  C12P7/18 ,  C12P7/40 ,  C12P7/42 ,  Y02E50/30

摘要： The invention provides non-naturally occurring microbial organisms containing enzymatic pathways and/or metabolic modifications for enhancing carbon flux through acetyl-CoA. In some embodiments, the microbial organisms having such pathways also include pathways for generating reducing equivalents, formaldehyde fixation and/or formate assimilation. The enhanced carbon flux through acetyl-CoA, in combination with pathways for generating reducing equivalents, formaldehyde fixation and/or formate assimilation can, in some embodiments, be used for production of a bioderived compound. Accordingly, in some embodiments, the microbial organisms of the invention can include a pathway capable of producing a bioderived compound of the invention. The invention still further provides a method for producing a bioderived compound of the invention.

公开(公告)号：EP3925997B1

公开(公告)日：2024-07-17

申请号：EP21178711.4

申请日：2006-04-21

IPC分类号： C08G63/16 ,  C08G63/20 ,  C08G63/78 ,  C08L67/02 ,  C08L1/00 ,  C08L5/00 ,  C08L99/00 ,  C12N15/52 ,  C12P7/18 ,  C12P7/44 ,  C12P7/46 ,  C12R1/13 ,  C08L3/00

CPC分类号： C08G63/20 ,  C08G63/78 ,  C08L1/00 ,  C08L3/00 ,  C08L5/00 ,  C08L67/02 ,  C08L99/00 ,  C08L2201/0620130101 ,  C08G63/16 ,  C12P7/18 ,  C12P7/46 ,  C12P7/44 ,  C12R2001/1320210501 ,  C12N15/52 ,  Y02W90/10

公开(公告)号：EP3592858B1

公开(公告)日：2024-06-12

申请号：EP18710031.8

申请日：2018-03-08

IPC分类号： C12P7/44 ,  C10B53/02 ,  C10C5/00 ,  C07C39/08 ,  C07C4/04 ,  C07C63/26 ,  C07D201/08 ,  C08L77/06 ,  C12N1/21 ,  C12N15/01

CPC分类号： C07C39/08 ,  C07C4/04 ,  C07D201/08 ,  C07C63/26 ,  C10B53/02 ,  C12P7/44 ,  C08L77/06 ,  Y02E50/10

公开(公告)号：EP4282965A1

公开(公告)日：2023-11-29

申请号：EP22774121.2

申请日：2022-03-17

申请人： Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences

发明人： SUN, Jibin ,  LIU, Jiao ,  ZHENG, Ping ,  SHI, Tuo ,  ZHOU, Wenjuan ,  MA, Yanhe

IPC分类号： C12N15/113 ,  C12N15/77 ,  C12N15/67 ,  C12N1/21 ,  C12N9/12 ,  C12P13/08 ,  C12P13/06 ,  C12P13/12 ,  C12P13/00 ,  C12P7/44 ,  C12R1/15

摘要： Disclosed are an aspartate kinase gene expression regulatory sequence and use thereof. By modifying positions 366-373 of a sequence represented by SEQ ID NO: 1, a polynucleotide formed by linking the sequence with a start codon GTG or TTG has transcriptional expression regulation activity, and these polynucleotides can improve the expression of the aspartate kinase encoding gene lysC, such that a large amount of L-lysine is accumulated.

公开(公告)号：EP4277728A1

公开(公告)日：2023-11-22

申请号：EP22700017.1

申请日：2022-01-05

申请人： BASF SE

发明人： WÖLFERT, Andreas ,  LORENZ, Michael ,  WATERS, Gerrit ,  REBLE, Marcus ,  FRIEDRICH, Holger ,  WEICKGENANNT, Andreas ,  GMEINER, Wolfgang

IPC分类号： B01D53/34 ,  B01D53/86 ,  C07C51/31 ,  C12P7/44

公开(公告)号：EP3967747B1

公开(公告)日：2023-11-08

申请号：EP21187599.2

申请日：2014-11-25

发明人： OSTERHOUT, Robin E. ,  BURGARD, Anthony P. ,  PHARKYA, Priti ,  ANDRAE, Stefan

IPC分类号： C12N1/19 ,  C12N1/15 ,  C12N1/13 ,  C12N1/11 ,  C12N15/70 ,  C12N15/81 ,  C12P7/42 ,  C12P5/02 ,  C12P13/00 ,  C12P17/10 ,  C12N1/14 ,  C12N1/20 ,  C12P7/02 ,  C12P7/40 ,  C12P7/04 ,  C12P7/44 ,  C12P7/18

公开(公告)号：EP3467113B1

公开(公告)日：2023-06-07

申请号：EP17806657.7

申请日：2017-05-30

发明人： ISOBE, Kyohei ,  KAWAMURA, Kenji ,  ITO, Masateru ,  YAMADA, Katsushige

IPC分类号： C12P7/44 ,  C12N1/20 ,  C12N1/21

公开(公告)号：EP3423563B1

公开(公告)日：2023-05-24

申请号：EP17760744.7

申请日：2017-03-01

发明人： SILLERS, Ryan ,  SPENCER, Michelle ,  YOCUM, R., Rogers ,  HERMANN, Theron ,  UDANI, Russell

IPC分类号： C12N1/21 ,  C12N15/09 ,  C12N15/52 ,  C12P7/44 ,  C12N15/60