公开(公告)号：JP2009209090A

公开(公告)日：2009-09-17

申请号：JP2008053697

申请日：2008-03-04

申请人： Mitsui Chemicals Inc ,  三井化学株式会社

发明人： KATSUTA HIROYUKI ,  KAI AKIYOSHI ,  WAKITA TAKEO ,  YOSHIDA KEI ,  KOBAYASHI YUMI ,  TAKAHASHI YUSUKE ,  TAKAHASHI KIYOSHI ,  TSUKADA HIDETAKA ,  NOMURA MICHIKAZU ,  DAIDO HIDENORI ,  KAWAHARA NOBUYUKI ,  INOMATA SHINICHI ,  KAWAHARA ATSUKO ,  MAKI JUNJI

IPC分类号： C07C235/56 ,  A01N37/22 ,  A01N43/40 ,  A01N47/20 ,  A01N47/30 ,  A01N51/00 ,  C07C233/66 ,  C07C233/78 ,  C07C235/78 ,  C07C237/40 ,  C07C237/52 ,  C07C243/38 ,  C07C257/02 ,  C07C257/18 ,  C07C261/04 ,  C07C271/22 ,  C07C271/28 ,  C07C271/44 ,  C07C271/58 ,  C07C275/24 ,  C07C275/40 ,  C07C279/36 ,  C07C311/08 ,  C07C311/21 ,  C07C311/44 ,  C07C311/47 ,  C07C323/12 ,  C07C327/32 ,  C07C335/16 ,  C07C335/20 ,  C07C335/22 ,  C07D213/36 ,  C07D213/81 ,  C07D213/82 ,  C07D295/22 ,  C07D307/20

摘要： PROBLEM TO BE SOLVED: To provide an insecticide which exhibits a high insecticidal effect even in a low dosage. SOLUTION: There are provided a compound represented by general formula (1) and an insecticide containing the compound as an active ingredient. In the formula (1), L 1 is Q 1 or D 1 Q 1 ; L 2 is Q 2 or D 2 Q 2 (wherein D 1 and D 2 represent various bonding manners; Q 1 is a 1-6C alkyl group, a 1-6C haloalkyl group, a substituted phenyl group, a substituted heterocyclic group, or the like; Q 2 is a substituted phenyl group, a substituted heterocyclic group, or the like); X is hydrogen atom or a halogen atom; n is an integer of 0-4; A is a carbon atom, a nitrogen atom, or the like which may be substituted with X; and K is a non-metallic atomic group necessary to form a 5- or 6-membered aromatic ring-derived cyclic bonding group together with A and the two carbon atoms to which A is bonded. COPYRIGHT: (C)2009,JPO&INPIT

摘要翻译： 待解决的问题：提供甚至在低剂量下也具有高杀虫作用的杀虫剂。 解决方案：提供由通式（1）表示的化合物和含有该化合物作为活性成分的杀虫剂。 在式（1）中，L 1 是Q 1 或D 1 1 SB。 L 2 是Q 2 或D 2 2 （其中D 1 和 D 2 表示各种键合方式; Q 1 是1-6C烷基，1-6C卤代烷基，取代苯基，取代的杂环基或 类似物; Q 2 是取代的苯基，取代的杂环基等）; X是氢原子或卤素原子; n是0-4的整数; A是可被X取代的碳原子，氮原子等; 并且K是与A和A键合的两个碳原子一起形成5-或6-元芳环来源的环状键合基团所必需的非金属原子团。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2010106031A

公开(公告)日：2010-05-13

申请号：JP2009294372

申请日：2009-12-25

申请人： Mitsui Chemicals Inc ,  三井化学株式会社

发明人： YOSHIDA KEI ,  WAKITA TAKEO ,  KATSUTA HIROYUKI ,  KAI AKIYOSHI ,  CHIBA YUTAKA ,  TAKAHASHI KIYOSHI ,  KATO HIROKO ,  KAWAHARA NOBUYUKI ,  NOMURA MICHIKAZU ,  DAIDO HIDENORI ,  MAKI JUNJI ,  BANBA SHINICHI ,  KAWAHARA ATSUKO

IPC分类号： C07C321/28 ,  A01N47/20 ,  C07C211/52 ,  C07C327/48 ,  C07C333/08 ,  C07D213/81

CPC分类号： A01N47/20 ,  C07C211/47 ,  C07C211/48 ,  C07C215/68 ,  C07C237/40 ,  C07C265/12 ,  C07C271/28 ,  C07C317/18 ,  C07C317/36 ,  C07C317/40 ,  C07C323/12 ,  C07C323/36 ,  C07C323/42 ,  C07C327/48 ,  C07C333/08 ,  C07C2601/04 ,  C07C2601/08 ,  C07D213/81

摘要： PROBLEM TO BE SOLVED: To provide intermediate aniline derivatives of insecticides having high effectiveness. SOLUTION: The aniline derivatives are represented by general formulae (8), (9). In the formula (8), R 7 is a 1-6C haloalkyl group; and Y 10 , Y 11 , Y 12 , Y 13 may be identical or different and each represents a hydrogen atom, a halogen atom, a 1-6C alkyl group or the like. In the formula (9), R 10 is a 1-6C haloalkyl group which may be substituted by at least one hydroxy group; and R 11 represents a hydrogen atom, a 1-4C alkyl group, a substituted m-nitrobenzoyl group or the like. COPYRIGHT: (C)2010,JPO&INPIT

摘要翻译： 要解决的问题：提供具有高效率的杀虫剂的中间体苯胺衍生物。 苯胺衍生物由通式（8），（9）表示。 在式（8）中，R SB为7-6个卤代烷基; 和Y 10 ，Y

公开(公告)号：JP2003306487A

公开(公告)日：2003-10-28

申请号：JP2002113303

申请日：2002-04-16

申请人： Mitsui Chemicals Inc ,  三井化学株式会社

发明人： ENOMOTO MIKI ,  MIYAHARA TORU ,  KAI AKIYOSHI ,  SATO KENICHI

IPC分类号： C07D333/36 ,  C07D409/12 ,  C07D411/12 ,  C07D417/12

摘要： PROBLEM TO BE SOLVED: To provide a method for the industrial production of a 3-acylamino- thiophene derivative from 2-carboxymethyl-3-amino-thienyl in high yield by 3 steps comprising amidation, demethylation and decarbonation.
SOLUTION: The improvement of the production method comprises the use of pyridine as the base to be used in the amidation reaction, the selection of a proper reaction solvent, the setting of the aging temperature in two steps, etc. The method is industrially advantageous because the 3 reaction stages can be carried out in the same reactor without separating the reaction product in each unit operation.
COPYRIGHT: (C)2004,JPO

摘要翻译： 待解决的问题：提供从2-羧甲基-3-氨基噻吩衍生物以高产率工业生产3步，包括酰胺化，去甲基化和脱碳的方法。 解决方案：生产方法的改进包括使用吡啶作为酰胺化反应中使用的碱，选择适当的反应溶剂，分两步设置老化温度等。方法是 工业上有利的是因为3个反应阶段可以在相同的反应器中进行，而不需要在每个单元操作中分离出反应产物。 版权所有（C）2004，JPO

公开(公告)号：JP2007099761A

公开(公告)日：2007-04-19

申请号：JP2006241058

申请日：2006-09-06

申请人： Mitsui Chemicals Inc ,  三井化学株式会社

发明人： WAKITA TAKEO ,  DAIDO HIDENORI ,  KAI AKIYOSHI ,  KAWAHARA NOBUYUKI ,  YOSHIDA KEI

IPC分类号： C07C271/28 ,  A01N37/22 ,  A01N41/06 ,  A01N47/10 ,  A01P3/00 ,  C07C237/42 ,  C07C311/09 ,  C07C323/36 ,  C07D213/82

摘要： PROBLEM TO BE SOLVED: To provide a compound exhibiting high insecticidal effect, and to provide an insecticide containing the compound. SOLUTION: The compound is represented by general formula (1) [wherein, A 1 , A 2 , A 3 and A 4 are C, N or the like; Z is -C(=G 1 )Q 1 , -C(=G 1 )G 2 G 3 , -SO 2 Q 1 or -Q 1 ; G 3 is O or the like; X is H, a halogen or the like; n is an integer of 0-4; Q 2 is phenyl, a heterocycle or the like; and R 1 and R 2 are a 1-4C alkoxycarbonyl or the like] and the insecticide contains the compound as an active ingredient. COPYRIGHT: (C)2007,JPO&INPIT

摘要翻译： 要解决的问题：提供具有高杀虫效果的化合物，并提供含有该化合物的杀虫剂。 解决方案：该化合物由通式（1）表示[其中，A 1 ，A 2 ，A 3 SB> 4 是C，N等; Z是-C（= G 1 ）Q 1 ，-C（= G 1 3 ，-SO 2 1 或-Q 1 。 G <3> 为O等; X是H，卤素等; n是0-4的整数; Q 2是苯基，杂环等; 和R SB 1和R SB 2是一个1-4C的烷氧基羰基等〕，杀虫剂含有该化合物作为活性成分。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2006306771A

公开(公告)日：2006-11-09

申请号：JP2005130675

申请日：2005-04-28

申请人： Mitsui Chemicals Inc ,  三井化学株式会社

发明人： KAI AKIYOSHI ,  WAKITA TAKEO ,  YOSHIDA KEI ,  KAWAHARA NOBUYUKI ,  NOMURA MICHIKAZU ,  DAIDO HIDENORI

IPC分类号： C07C237/42 ,  A01N37/34 ,  A01N37/46 ,  A01N43/08 ,  A01N43/10 ,  A01N43/16 ,  A01N43/24 ,  A01N43/36 ,  A01N43/40 ,  A01N43/713 ,  A01N43/78 ,  C07C255/19 ,  C07C255/41 ,  C07C255/46 ,  C07C317/40 ,  C07C317/44 ,  C07C323/42 ,  C07C323/60 ,  C07D309/28

摘要： PROBLEM TO BE SOLVED: To provide an agricultural/horticultural insecticide having excellent insecticidal efficiency. SOLUTION: This insecticide includes as an effective component, a compound represented by general formula (1) (wherein A 1 to A 4 are each C, N or the like; R 1 is 1-6C alkyl; R 2 and R 3 are each H, 1-4C alkyl, 1-4C alkylcarbonyl or the like; G 1 and G 3 are each O or S; X is H, halogen, 1-4C alkyl, amino or the like; n is an integer of 0 to 4; and Q is phenyl, naphthyl, tetrahydronaphthyl, heterocyclic aromatic or the like). COPYRIGHT: (C)2007,JPO&INPIT

摘要翻译： 要解决的问题：提供具有优异杀虫效率的农业/园艺杀虫剂。 解决方案：该杀虫剂包括作为有效成分的由通式（1）表示的化合物（其中A 1 至A 4 分别为C，N或 R SB 1是C 1-6烷基; R SB 2和R SB 3各自为H，1-4C烷基，1-4C烷基羰基或 类似物; G 1 和G 3 各自为O或S; X为H，卤素，1-4C烷基，氨基等; n为整数0 至4; Q为苯基，萘基，四氢萘基，杂环芳族等）。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2006225340A

公开(公告)日：2006-08-31

申请号：JP2005042338

申请日：2005-02-18

申请人： MITSUI CHEMICALS INC

发明人： TAKAHASHI KIYOSHI ,  KAI AKIYOSHI ,  WAKITA TAKEO

IPC分类号： C07C271/28 ,  A01N47/20 ,  C07C269/06 ,  C07D213/81 ,  C07D213/89

摘要： PROBLEM TO BE SOLVED: To provide a method for producing an insecticide for agriculture and horticulture expressed by general formula (1). SOLUTION: The insecticide for agriculture and horticulture is a compound expressed by general formula (1) and produced by using production intermediates expressed by general formula (2) and general formula (3), wherein A 1 , A 2 , A 3 and A 4 express each a carbon atom or the like; R 1 expresses an alkyl or the like; R 2 and R 3 express each H or the like; G 1 , G 2 and G 3 express each O or the like; X expresses H or the like; R a and R b express each F or the like; R c expresses a halogen atom or the like; Y 1 , Y 2 , Y 4 and Y 5 express each H or the like. COPYRIGHT: (C)2006,JPO&NCIPI

公开(公告)号：JP2000080066A

公开(公告)日：2000-03-21

申请号：JP16945199

申请日：1999-06-16

申请人： MITSUI CHEMICALS INC

发明人： YAMASHITA HIROYUKI ,  TOGASHI KAZUHIKO ,  KAI AKIYOSHI ,  MORI JUNICHI ,  MORI HARUKI ,  KAWAI KOICHI ,  KOYABE AKIHIRO ,  SATO TAKASHI

IPC分类号： C07D295/08 ,  A61K31/00 ,  A61K31/165 ,  A61K31/167 ,  A61K31/34 ,  A61K31/341 ,  A61K31/35 ,  A61K31/351 ,  A61K31/40 ,  A61K31/445 ,  A61K31/535 ,  A61K31/5375 ,  A61P9/00 ,  A61P9/06 ,  C07C235/64 ,  C07C311/08 ,  C07C317/44 ,  C07D307/22 ,  C07D307/68 ,  C07D309/08

摘要： PROBLEM TO BE SOLVED: To obtain a new anilide derivative useful as an active ingredient for new type antiarrhythmic medicines having high safety and free from a ventricular function-inhibiting action and an arhythmia-stimulating action. SOLUTION: An anilide derivative of formula I (R1 is a 1-3C alkoxy, a 1-3C alkyl or the like; R2, R3 are each H, a 1-3C alkoxy, a 1-3C alkyl or the like; R4, R5 are each H, a 1-4C alkyl, a 3-6C cycloalkyl or the like) or its pharmacologically acceatable salt, for examale, 4'-[2-(ethylamino) ethoxy]-2-(methanesulfonamido)benzanilide. The anilide derivative of formula I is obtained, for example, by condensing a carboxylic acid derivative of formula II with an aniline derivative of formula III in the presence of a condensing agent such as dicyclohexylcarbodiimide or carbonyldiimidazole. The anilide derivative of formula I can be used as an active ingredient to provide an antiarrhythmic medicine not affecting an ventricular function, especially an auricular arrhythmia-treating medicine.

公开(公告)号：JP2002167388A

公开(公告)日：2002-06-11

申请号：JP2001220077

申请日：2001-07-19

申请人： MITSUI CHEMICALS INC

发明人： SUZUKI TSUNESHI ,  NAGASE HIROSHI ,  KAI AKIYOSHI ,  IIZUKA HAJIME

IPC分类号： C07H1/00 ,  C07D498/14 ,  C07H19/067

摘要： PROBLEM TO BE SOLVED: To provide an 2,2'-anhydro nucleic acid compound derivative and a L-cytidine derivative which are useful as intermediates of drugs and pesticides using inexpensive compounds as starting materials. SOLUTION: The 2,2'-anhydro nucleic acid compound derivative is obtained by reacting a compound represented by formula (2) [wherein, R1, R2, R3, R4, Q, X, Y and Z are each independently a particular group] with a compound represented by formula (3). With this reaction, the 2,2'-anhydro nucleic acid compound derivative useful as an intermediate of drugs and pesticides can be obtained from inexpensive compounds as starting materials. The L-cytidine derivative useful as an intermediate of drugs and pesticides can be obtained by synthesizing 2'-alkoxy cytidine directly from a 2,2'-anhydro cytidine derivative.

公开(公告)号：JP2001270858A

公开(公告)日：2001-10-02

申请号：JP2000085460

申请日：2000-03-27

申请人： MITSUI CHEMICALS INC

发明人： YAMASHITA HIROYUKI ,  MORI HARUKI ,  TOGASHI KAZUHIKO ,  KAI AKIYOSHI ,  MORI JUNICHI

IPC分类号： C07C235/16 ,  C07C309/66 ,  C07C309/73

摘要： PROBLEM TO BE SOLVED: To obtain a new aminophenol derivative useful as an intermediate for medicaments/agrochemicals, or the like. SOLUTION: This aminophenol derivative is represented by general formula (1) [wherein, R1 is a 1-4C alkyl; (n) is an integer of 2 or 3; and R2 is H or (CH2)mR3 ((m) is an integer of 2 or 3; R3 is OH, a halogen atom, methanesulfonyloxy group or p-toluenesulfonyloxy group)].

公开(公告)号：JP2001151742A

公开(公告)日：2001-06-05

申请号：JP33524499

申请日：1999-11-26

申请人： MITSUI CHEMICALS INC

发明人： YAMASHITA HIROYUKI ,  TOGASHI KAZUHIKO ,  KAI AKIYOSHI ,  MORI JUNICHI ,  MORI HARUKI ,  KAWAI KOICHI ,  KOYABE AKIHIRO ,  SATO TAKASHI

IPC分类号： C07D295/00 ,  A61K31/167 ,  A61K31/40 ,  A61K31/4453 ,  A61K31/5375 ,  A61P9/06 ,  C07C235/64 ,  C07C235/88 ,  C07C237/42 ,  C07C237/50

摘要： PROBLEM TO BE SOLVED: To obtain a new antiarrhythmic agent having no effect on cardiac function. SOLUTION: This antiarrhythmic agent comprises a new anilide derivative represented by the general formula. The antiarrhythmic agent is applicable also to patients lowered in cardiac function and excellent in safety.