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公开(公告)号：US08062372B2
公开(公告)日：2011-11-22
申请号：US11611821
申请日：2006-12-15
申请人： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
发明人： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61F2/30771 , A61F2002/2835 , A61F2002/3008 , A61F2002/30153 , A61F2002/30163 , A61F2002/30171 , A61F2002/30772 , A61F2002/4629 , A61F2230/0019 , A61F2230/0028 , A61F2230/005 , A61F2250/0098 , A61F2310/00179 , A61F2310/00365
摘要： A spinal fusion device abutting and fixed between adjacent vertebrae. The spinal fusion device includes a support frame. The support frame has a plurality of extending bodies, each radially extending from a center of the support frame. A predetermined gap exists between every two adjacent extending bodies, receiving a bone graft.
摘要翻译： 脊椎融合装置邻接并固定在相邻的椎骨之间。 脊柱融合装置包括支撑框架。 支撑框架具有多个延伸体，每个延伸体从支撑框架的中心径向延伸。 在每两个相邻的延伸体之间存在预定的间隙，接收骨移植物。
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公开(公告)号：US20070156240A1
公开(公告)日：2007-07-05
申请号：US11611821
申请日：2006-12-15
申请人： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
发明人： Yang-Hwei Tsuang , Jui-Sheng Sun , Chun-Jen Liao , Chen-Chi Tsai , Shan-Chang Chueh , Yi-Hung Lin , Shian-Yih Wang , I-Fan Chiu
IPC分类号： A61F2/44
CPC分类号： A61F2/4455 , A61F2/30771 , A61F2002/2835 , A61F2002/3008 , A61F2002/30153 , A61F2002/30163 , A61F2002/30171 , A61F2002/30772 , A61F2002/4629 , A61F2230/0019 , A61F2230/0028 , A61F2230/005 , A61F2250/0098 , A61F2310/00179 , A61F2310/00365
摘要： A spinal fusion device abutting and fixed between adjacent vertebrae. The spinal fusion device includes a support frame. The support frame has a plurality of extending bodies, each radially extending from a center of the support frame. A predetermined gap exists between every two adjacent extending bodies, receiving a bone graft.
摘要翻译： 脊椎融合装置邻接并固定在相邻的椎骨之间。 脊柱融合装置包括支撑框架。 支撑框架具有多个延伸体，每个延伸体从支撑框架的中心径向延伸。 在每两个相邻的延伸体之间存在预定的间隙，接收骨移植物。
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公开(公告)号：US20050133447A1
公开(公告)日：2005-06-23
申请号：US10962609
申请日：2004-10-13
申请人： Chen-Chi Tsai , Yung-Chih Wu
发明人： Chen-Chi Tsai , Yung-Chih Wu
摘要： The present invention relates to a process and apparatus for separating blood plasma, having a mixing unit in the form of a first injection having a first connecting tube and a first piston to provide a compartment for a mixture composed of plasma to be separated and the protein-precipitating agent; a separating unit composed of a filtering tube for separating and preserving a solid material after separation. The filtering tube includes a third connecting tube a filter and a third piston, the third connecting tube communicates with the fourth injection tube having a fourth piston for receiving a separated liquid; and a storage unit in the form of a fifth injection tube having a fifth connecting tube, a second connecting valve and a fifth piston.
摘要翻译： 本发明涉及一种用于分离血浆的方法和装置，其具有第一注射形式的混合单元，其具有第一连接管和第一活塞，以提供由待分离血浆组成的混合物的隔室和蛋白质 - 沉淀剂; 分离单元，由分离后分离保存固体物质的过滤管构成。 过滤管包括第三连接管，过滤器和第三活塞，第三连接管与第四注入管连通，具有用于接收分离液体的第四活塞; 以及具有第五连接管，第二连接阀和第五活塞的第五注入管形式的存储单元。
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4.发明授权公开(公告)号：US07700355B2
公开(公告)日：2010-04-20
申请号：US11030150
申请日：2005-01-07
申请人： Chun-Jen Liao , Jui-Hsiang Chen , Chen-Chi Tsai , Yung-Chih Wu , Shu-Fang Chiang , Yi-Jung Hsiang
发明人： Chun-Jen Liao , Jui-Hsiang Chen , Chen-Chi Tsai , Yung-Chih Wu , Shu-Fang Chiang , Yi-Jung Hsiang
CPC分类号： C12N5/0068 , A61L27/46 , A61L27/56 , C12N2533/18 , C08L5/04
摘要： A porous matrix, preparation thereof, and methods of using the same. The porous matrix of calcium alginate is prepared using a plurality of particles containing a multivalent cation, admixing the particles with ionic cross-linked polysaccharides and water to form a mixture, introducing a cross linker to solidify the mixture, dissolving the particles of the mixture in an acid to form a porous structure, and neutralizing and cross-linking the porous structure.
摘要翻译： 多孔基体，其制备方法及其使用方法。 藻酸钙的多孔基质是使用多个含有多价阳离子的颗粒制备的，将颗粒与离子交联的多糖和水混合以形成混合物，引入交联剂固化混合物，将混合物的颗粒溶解在 酸形成多孔结构，中和并交联多孔结构。
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5.发明申请Surface modification of polysaccharide, the modified polysaccharide, and method of culturing and recovery cells using the same 有权多糖的表面改性，改性多糖，以及使用该多糖的培养和回收细胞的方法公开(公告)号：US20070148768A1
公开(公告)日：2007-06-28
申请号：US11384386
申请日：2006-03-21
申请人： Chun-Jen Liao , Yung-chih Wu , Chen-Chi Tsai , Hsiang-Ming Huang , Yuan-Hua Hsu , Shu-Fang Chiang
发明人： Chun-Jen Liao , Yung-chih Wu , Chen-Chi Tsai , Hsiang-Ming Huang , Yuan-Hua Hsu , Shu-Fang Chiang
CPC分类号： C12N5/0068 , C12N2500/10 , C12N2533/50 , C12N2533/54 , C12N2533/70 , C12N2533/72 , C12N2533/74
摘要： A surface modification method of polysaccharide, the modified polysaccharide, and a method of culturing and recovery cells using the same are provided. The surface modification method of polysaccharide comprises (a) immersing a polysaccharide material in an acid, (b) immersing the polysaccharide material in an acidic solution containing a protein, and (c) immersing the polysaccharide material in an alkaline solution containing bivalent metal ions.
摘要翻译： 提供了多糖，改性多糖的表面改性方法，以及使用其的培养和回收细胞的方法。 多糖的表面改性方法包括（a）将多糖材料浸入酸中，（b）将多糖材料浸入含有蛋白质的酸性溶液中，（c）将多糖材料浸入含有二价金属离子的碱性溶液中。
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6.发明授权Surface modification of polysaccharide, the modified polysaccharide, and method of culturing and recovery cells using the same 有权多糖的表面改性，改性多糖，以及使用该多糖的培养和回收细胞的方法公开(公告)号：US07906333B2
公开(公告)日：2011-03-15
申请号：US11384386
申请日：2006-03-21
申请人： Chun-Jen Liao , Yung-chih Wu , Chen-Chi Tsai , Hsiang-Ming Huang , Yuan-Hua Hsu , Shu-Fang Chiang
发明人： Chun-Jen Liao , Yung-chih Wu , Chen-Chi Tsai , Hsiang-Ming Huang , Yuan-Hua Hsu , Shu-Fang Chiang
IPC分类号： C12N5/00 , A61K31/715
CPC分类号： C12N5/0068 , C12N2500/10 , C12N2533/50 , C12N2533/54 , C12N2533/70 , C12N2533/72 , C12N2533/74
摘要： A surface modification method of polysaccharide, the modified polysaccharide, and a method of culturing and recovery cells using the same are provided. The surface modification method of polysaccharide comprises (a) immersing a polysaccharide material in an acid, (b) immersing the polysaccharide material in an acidic solution containing a protein, and (c) immersing the polysaccharide material in an alkaline solution containing bivalent metal ions.
摘要翻译： 提供了多糖，改性多糖的表面改性方法，以及使用其的培养和回收细胞的方法。 多糖的表面改性方法包括（a）将多糖材料浸入酸中，（b）将多糖材料浸入含有蛋白质的酸性溶液中，（c）将多糖材料浸入含有二价金属离子的碱性溶液中。
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公开(公告)号：US20080110831A1
公开(公告)日：2008-05-15
申请号：US11976798
申请日：2007-10-29
申请人： Chen-Chi Tsai , Yung-Chih Wu
发明人： Chen-Chi Tsai , Yung-Chih Wu
IPC分类号： B01D61/00
摘要： The present invention relates to a process and apparatus for separating blood plasma, having a mixing unit in the form of a first injection having a first connecting tube and a first piston to provide a compartment for a mixture composed of plasma to be separated and the protein-precipitating agent; a separating unit composed of a filtering tube for separating and preserving a solid material after separation. The filtering tube includes a third connecting tube a filter and a third piston, the third connecting tube communicates with the fourth injection tube having a fourth piston for receiving a separated liquid; and a storage unit in the form of a fifth injection tube having a fifth connecting tube, a second connecting valve and a fifth piston.
摘要翻译： 本发明涉及一种用于分离血浆的方法和装置，其具有第一注射形式的混合单元，其具有第一连接管和第一活塞，以提供由待分离血浆组成的混合物的隔室和蛋白质 - 沉淀剂; 分离单元，由分离后分离保存固体物质的过滤管构成。 过滤管包括第三连接管，过滤器和第三活塞，第三连接管与第四注入管连通，具有用于接收分离液体的第四活塞; 以及具有第五连接管，第二连接阀和第五活塞的第五注入管形式的存储单元。
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公开(公告)号：US07481941B2
公开(公告)日：2009-01-27
申请号：US11976798
申请日：2007-10-29
申请人： Chen-Chi Tsai , Yung-Chih Wu
发明人： Chen-Chi Tsai , Yung-Chih Wu
IPC分类号： B01D61/14
摘要： The present invention relates to a process and apparatus for separating blood plasma, having a mixing unit in the form of a first injection having a first connecting tube and a first piston to provide a compartment for a mixture composed of plasma to be separated and the protein-precipitating agent; a separating unit composed of a filtering tube for separating and preserving a solid material after separation. The filtering tube includes a third connecting tube a filter and a third piston, the third connecting tube communicates with the fourth injection tube having a fourth piston for receiving a separated liquid; and a storage unit in the form of a fifth injection tube having a fifth connecting tube, a second connecting valve and a fifth piston.
摘要翻译： 本发明涉及一种用于分离血浆的方法和装置，其具有第一注射形式的混合单元，其具有第一连接管和第一活塞，以提供由待分离血浆组成的混合物的隔室和蛋白质 - 沉淀剂; 分离单元，由分离后分离保存固体物质的过滤管构成。 过滤管包括第三连接管，过滤器和第三活塞，第三连接管与第四注入管连通，具有用于接收分离液体的第四活塞; 以及具有第五连接管，第二连接阀和第五活塞的第五注入管形式的存储单元。
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9.发明申请公开(公告)号：US20080233552A1
公开(公告)日：2008-09-25
申请号：US11689933
申请日：2007-03-22
申请人： David Hui-Kang Ma , Jan-Kan Chen , Chen-Chi Tsai
发明人： David Hui-Kang Ma , Jan-Kan Chen , Chen-Chi Tsai
IPC分类号： A01N1/00
CPC分类号： A61K35/50 , A61L27/3604 , A61L27/3687 , A61L27/3691 , A61L2430/40
摘要： The present invention discloses a method of cross-linking amnion to be an improved biomedical material. The present invention adopts the amnion cross-linked by EDC (N-(3-dimethylaminopropyl)-N′-ethyl-carbodiimide HCI) or NHS (N-hydroxysuccinimide), and the cross-linked amnion not only has more resistance to protease, but also binds specific extracellular matrix (ECM) such as heparin by using cross-linked functional group. Further, by using the affinity of the ECM with specific growth factors, the amnion can be an efficient carrier for specific growth factor. Hence, some specific diseases may be treated.
摘要翻译： 本发明公开了将羊膜交联成为改进的生物医学材料的方法。 本发明采用EDC（N-（3-二甲基氨基丙基）-N'-乙基碳二亚胺HCl）或NHS（N-羟基琥珀酰亚胺）交联的羊膜，交联羊膜不仅对蛋白酶具有更强的抗性， 而且通过使用交联官能团结合特异性细胞外基质（ECM）如肝素。 此外，通过使用ECM与特定生长因子的亲和力，羊膜可以是特定生长因子的有效载体。 因此，一些特定的疾病可以被治疗。
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公开(公告)号：US07309428B2
公开(公告)日：2007-12-18
申请号：US10962609
申请日：2004-10-13
申请人： Chen-Chi Tsai , Yung-Chih Wu
发明人： Chen-Chi Tsai , Yung-Chih Wu
摘要： The present invention relates to a process and apparatus for separating blood plasma, having a mixing unit in the form of a first injection having a first connecting tube and a first piston to provide a compartment for a mixture composed of plasma to be separated and the protein-precipitating agent; a separating unit composed of a filtering tube for separating and preserving a solid material after separation. The filtering tube includes a third connecting tube a filter and a third piston, the third connecting tube communicates with the fourth injection tube having a fourth piston for receiving a separated liquid; and a storage unit in the form of a fifth injection tube having a fifth connecting tube, a second connecting valve and a fifth piston.
摘要翻译： 本发明涉及一种用于分离血浆的方法和装置，其具有第一注射形式的混合单元，其具有第一连接管和第一活塞，以提供由待分离血浆组成的混合物的隔室和蛋白质 - 沉淀剂; 分离单元，由分离后分离保存固体物质的过滤管构成。 过滤管包括第三连接管，过滤器和第三活塞，第三连接管与第四注入管连通，具有用于接收分离液体的第四活塞; 以及具有第五连接管，第二连接阀和第五活塞的第五注入管形式的存储单元。
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