Patent search ap:"Han LI" Page 1

1.

发明授权
Hydroxytyrosol sturgeon skin gelatin film with antioxidant activity and Salmonella detection ability and a method of preparing the same 有权

公开(公告)号：US11639516B2

公开(公告)日：2023-05-02

申请号：US16752573

申请日：2020-01-24

Applicant: Chengyuan Liang , Qi Lu , Liang Xin , Guaiping Qiao , Jingyi Li , Kangxiong Wu , Han Li , Bin Tian

Inventor： Chengyuan Liang , Qi Lu , Liang Xin , Guaiping Qiao , Jingyi Li , Kangxiong Wu , Han Li , Bin Tian

IPC: C12Q1/04 , C07K14/78

Abstract: A method of preparing a hydroxytyrosol sturgeon skin gelatin film with antioxidant activity and Salmonella detection ability includes: (1) mixing a neutral red indicator solution and distilled water at room temperature to obtain a mixture solution, and adding 1 mol/L NaHCO3 solution to the mixture solution until discoloration to obtain an alkaline solution; (2) adding an amount of the alkaline solution obtained in step (1) to a mixture of Sturgeon skin gelatin and distilled water to obtain an alkaline gelatin solution; (3) adding hydroxytyrosol and glycerin and propylene glycol to the alkaline gelatin solution to obtain a hydroxytyrosol gelatin solution, and heating the hydroxytyrosol gelatin solution at 40-70° C.; (4) ultrasonicating the hydroxytyrosol gelatin solution from step (3), placing the hydroxytyrol gelatin solution evenly on a clean plexiglass plate, drying the hydroxytyrol gelatin solution on an ultra-clean worktable to obtain the hydroxytyrosol sturgeon skin gelatin film.

2.

发明授权
Pleuromutilin (phenylthio)acetic acid ester with anti-drug resistant bacteria activity and a method of preparing the same 有权

公开(公告)号：US11518740B2

公开(公告)日：2022-12-06

申请号：US17239575

申请日：2021-04-24

Applicant: Qianqian Zhao , Jie Zhang , Liang Xin , Jingyi Li , Ruina Bian , Yuqing Zhao , Dan Yang , Han Li , Bin Tian , Yongbo Wang , Chengyuan Liang

Inventor： Qianqian Zhao , Jie Zhang , Liang Xin , Jingyi Li , Ruina Bian , Yuqing Zhao , Dan Yang , Han Li , Bin Tian , Yongbo Wang , Chengyuan Liang

IPC: C07C323/52 , C07C319/20

Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

3.

发明申请
PLEUROMUTILIN 2-[(DIPHENYLMETHYL)THIO]ACETIC ACID ESTER WITH ANTI-DRUG RESISTANT BACTERIA ACTIVITY AND A METHOD OF PREPARING THE SAME 有权

公开(公告)号：US20220348540A1

公开(公告)日：2022-11-03

申请号：US17239582

申请日：2021-04-24

Applicant: Dan YANG , Jingyi LI , Liang XIN , Ruina BIAN , Jie ZHANG , Qianqian ZHAO , Yuqing ZHAO , Han LI , Bin TIAN , Yongbo WANG , Chengyuan LIANG , Liang QI , Gennian MAO

Inventor： Dan YANG , Jingyi LI , Liang XIN , Ruina BIAN , Jie ZHANG , Qianqian ZHAO , Yuqing ZHAO , Han LI , Bin TIAN , Yongbo WANG , Chengyuan LIANG , Liang QI , Gennian MAO

IPC: C07C323/52 , A61P31/04 , C07C319/28

Abstract: A compound with anti-drug resistant bacteria activity having the formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

4.

发明授权
Method of preparing hydroxytyrosol cinnamic acid ester with antioxidant and antibacterial activities 有权

公开(公告)号：US11427526B2

公开(公告)日：2022-08-30

申请号：US17026224

申请日：2020-09-19

Applicant: Jia Wan , Jie Zhang , Chunchun Kong , Yi Jin , Min Fan , Han Li , Qiaoqiao Zhao , Dan Yang

Inventor： Jia Wan , Jie Zhang , Chunchun Kong , Yi Jin , Min Fan , Han Li , Qiaoqiao Zhao , Dan Yang

IPC: C07C67/40 , A01N37/00 , C07C69/73

Abstract: A method of preparing a compound of formula (I): is disclosed. The compound of formula (I) can be used as an antioxidant agent. The compound can also be used as an antibacterial agent to inhibit Staphylococcus aureus MRSA 18-222 and Pseudomonas aeruginosa MDR-PA 18-1774.

5.

发明申请
SILIBININ LIPOIC ACID ESTER WITH HEPATOPROTECTIVE ACTIVITY AND A METHOD OF PREPARING THE SAME 有权

公开(公告)号：US20210347767A1

公开(公告)日：2021-11-11

申请号：US16871354

申请日：2020-05-11

Applicant: Xingke JU , Chengyuan LIANG , Yuzhi LIU , Bin TIAN , Lei TIAN , Gennian MAO , Limei WANG , Yuanyuan HE , Yongbo WANG , Jingwen XU , Dan YANG , Liang QI , Wenbo YAO , Qianqian ZHAO , Han LI

Inventor： Xingke JU , Chengyuan LIANG , Yuzhi LIU , Bin TIAN , Lei TIAN , Gennian MAO , Limei WANG , Yuanyuan HE , Yongbo WANG , Jingwen XU , Dan YANG , Liang QI , Wenbo YAO , Qianqian ZHAO , Han LI

IPC: C07D409/14 , B01J27/24

Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

6.

发明授权
Pleuromulin tretinoin ester with antibacterial activity and a method of preparing the same 有权

公开(公告)号：US11168049B1

公开(公告)日：2021-11-09

申请号：US17128100

申请日：2020-12-19

Applicant: Yonghong Tang , Minghui Chang , Huafeng Qi , Bin Tian , Juan Li , Liang Xin , Jingyi Li , Dan Yang , Han Li , Yanjun Li , Liang Qi , Wenbo Yao , Chengyuan Liang

Inventor： Yonghong Tang , Minghui Chang , Huafeng Qi , Bin Tian , Juan Li , Liang Xin , Jingyi Li , Dan Yang , Han Li , Yanjun Li , Liang Qi , Wenbo Yao , Chengyuan Liang

IPC: C07C69/732 , C07C67/08

Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

7.

发明授权
Hydroxytyrosol ursolic acid ester with antioxidant activity and methods of preparing the same 有权

公开(公告)号：US10995053B1

公开(公告)日：2021-05-04

申请号：US16826045

申请日：2020-03-20

Applicant: Han Li , Nan Hui , Bin Tian , Xingke Ju , Yuzhi Liu , Dan Yang , Jingwen Xu , Liang Qi , Qianqian Zhao , Yongbo Wang

Inventor： Han Li , Nan Hui , Bin Tian , Xingke Ju , Yuzhi Liu , Dan Yang , Jingwen Xu , Liang Qi , Qianqian Zhao , Yongbo Wang

IPC: C07C67/08 , B01J20/291 , B01J31/02

Abstract: A compound having the formula (I): is disclosed. Methods of preparing the compound of formula (I) are also disclosed. The compound of formula (I) can be prepared by reacting a compound of formula (II) with a compound of formula (III) in an organic solvent with EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide). The compound of formula (I) can also be prepared by reacting the compound of formula (II) with the compound of formula (III) in 1-ethyl-3-methylimidazolium hexafluorophosphate as a solvent with silicomolybdic acid as a catalyst.