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    Composite membranes for liquid filtration having improved uniformity and adhesion of substrate to membrane
    2.
    发明申请
    Composite membranes for liquid filtration having improved uniformity and adhesion of substrate to membrane 有权
    用于液体过滤的复合膜具有改善的基底与膜的均匀性和粘附性

    公开(公告)号：US20070138084A1

    公开(公告)日：2007-06-21

    申请号：US11304344

    申请日：2005-12-15

    申请人： Jennifer Galvin ,  Henricus Gommeren ,  Rachel Montejo ,  Tina Waller

    发明人： Jennifer Galvin ,  Henricus Gommeren ,  Rachel Montejo ,  Tina Waller

    IPC分类号： B01D71/06

    CPC分类号： B01D69/12 ,  B01D69/10

    摘要： An improved casting substrate is provided for use in a composite membrane for use as a fluid filtration medium. The composite membrane has good adhesion between the casting substrate and the microporous membrane while maintaining high permeability. The casting substrate comprises a single spunbond layer or a multiple spunbond layers formed of thermoplastic fibers, optionally comprising at least one meltblown layer. The casting substrate allows the membrane casting solution to penetrate the casting substrate uniformly to a controlled depth without penetrating through the entire thickness of the substrate. The casting substrate has good uniformity of mean pore size, basis weight, thickness and surface roughness.

    摘要翻译： 提供了一种改进的流延基材，用于复合膜，用作流体过滤介质。 复合膜在保持高渗透性的同时，具有良好的铸塑基材与微孔膜的粘附性。 浇铸基材包括单个纺粘层或由热塑性纤维形成的多个纺粘层，任选地包含至少一个熔喷层。 铸造基底允许膜浇铸溶液均匀地穿透铸造基底至受控的深度，而不穿透基底的整个厚度。 铸造基材的平均孔径，基重，厚度和表面粗糙度均匀性好。

    Filtration media for liquid filtration
    4.
    发明申请
    Filtration media for liquid filtration 有权
    滤液用于液体过滤

    公开(公告)号：US20070075015A1

    公开(公告)日：2007-04-05

    申请号：US11240517

    申请日：2005-09-30

    申请人： W. Bates ,  Henricus Gommeren ,  Hageun Suh

    发明人： W. Bates ,  Henricus Gommeren ,  Hageun Suh

    IPC分类号： B01D24/00

    CPC分类号： B01D39/1623 ,  B01D2239/025 ,  B01D2239/0258 ,  D04H1/54 ,  D04H1/5405 ,  D04H1/559 ,  D04H1/56 ,  D04H1/728 ,  D04H3/04 ,  D04H13/002 ,  D04H13/007

    摘要： Filtration media including at least one layer of nanofibers having average diameters less than 1000 nanometers with optional scrim layer(s) are disclosed for filtering particulate matter in liquid. The media achieve flow rates of at least 0.055 L/min/cm2 at relatively high levels of solidity. The media have also advantageously been found to have non-diminishing flow rates as differential pressures increase between 2 psi (14 kPa) and 15 psi (100 kPa).

    摘要翻译： 公开了用于过滤液体中的颗粒物质的包含至少一层具有平均直径小于1000纳米的纳米纤维的过滤介质和可选的稀松布层。 介质以相当高的固体水平实现至少0.055L / min / cm 2的流速。 当差压在2psi（14kPa）和15psi（100kPa）之间增加时，介质也有利地被发现具有不减小的流速。

    Intimate coating of ibuprofen with poloxamers to enhance aqueous dissolution
    5.
    发明申请
    Intimate coating of ibuprofen with poloxamers to enhance aqueous dissolution 审中-公开
    布洛芬与泊洛沙姆的亲和涂层以增强水溶解度

    公开(公告)号：US20060013871A1

    公开(公告)日：2006-01-19

    申请号：US11201890

    申请日：2005-08-11

    申请人： Larry Berger ,  Madurai Ganesan ,  Nutan Gangrade ,  Henricus Gommeren ,  Torrence Trout

    发明人： Larry Berger ,  Madurai Ganesan ,  Nutan Gangrade ,  Henricus Gommeren ,  Torrence Trout

    IPC分类号： A61K9/20 ,  A61K9/36

    CPC分类号： A61K31/445 ,  A61K9/1635 ,  A61K9/2077 ,  A61K9/5026

    摘要： This invention provides methods for enhancing the dissolution rate of Ibuprofen. More particularly, the invention provides a process for enhancing the solubility of Ibuprofen by intimately coating Ibuprofen particles with a Poloxamer. The invention also provides for a composition comprising a solid dosage form of Ibuprofen, wherein the surfaces of Ibuprofen particles have been intimately coated with a Poloxamer; a composition comprising a fast onset, solid dosage form of Ibuprofen; and a composition comprising Ibuprofen particles intimately coated with a Poloxamer.

    摘要翻译： 本发明提供了提高布洛芬溶出速率的方法。 更具体地，本发明提供了通过用泊洛沙姆紧密涂布布洛芬颗粒来增强布洛芬的溶解度的方法。 本发明还提供包含布洛芬固体剂型的组合物，其中布洛芬颗粒的表面已用泊洛沙姆密封; 包含快速起效的布洛芬固体剂型的组合物; 以及包含用泊洛沙姆密封涂布的布洛芬颗粒的组合物。