公开(公告)号：US09994618B2

公开(公告)日：2018-06-12

申请号：US14418004

申请日：2013-07-30

Applicant: Hong-Jin Kim

Inventor： Hong-Jin Kim ,  Hyoung Jin Kim

IPC: C07K14/005 ,  C07K14/025 ,  C12N7/00 ,  C12N7/02 ,  A61K39/00 ,  A61K39/12

CPC classification number: C07K14/005 ,  A61K39/00 ,  C12N7/00 ,  C12N2710/20034 ,  C12N2710/20051

Abstract: Provided is a method of purifying human papillomavirus (HPV) L1 proteins with high purity and high efficiency. According to the purification method, a purification purity and yield of HPV L1 proteins can be considerably increased when heating/chilling is formed by treating a cell homogenate with a reducing agent. In addition, VLPs of the HPV L1 protein purified by the purification method have excellent antigenicity and immunogenicity.

公开(公告)号：US20150266927A1

公开(公告)日：2015-09-24

申请号：US14418004

申请日：2013-07-30

Applicant: Hong-Jin KIM

Inventor： Hong-Jin Kim ,  Hyoung Jin Kim

IPC: C07K14/005 ,  C12N7/00

CPC classification number: C07K14/005 ,  A61K39/00 ,  C12N7/00 ,  C12N2710/20034 ,  C12N2710/20051

Abstract: Provided is a method of purifying human papillomavirus (HPV) L1 proteins with high purity and high efficiency. According to the purification method, a purification purity and yield of HPV L1 proteins can be considerably increased when heating/chilling is formed by treating a cell homogenate with a reducing agent. In addition, VLPs of the HPV L1 protein purified by the purification method have excellent antigenicity and immunogenicity.

Abstract translation: 提供了一种纯化和高效率纯化人乳头状瘤病毒（HPV）L1蛋白的方法。 根据纯化方法，当通过用还原剂处理细胞匀浆而加热/冷却时，可以显着增加HPV L1蛋白的纯化纯度和产率。 此外，通过纯化方法纯化的HPV L1蛋白的VLP具有优异的抗原性和免疫原性。

公开(公告)号：US20140297300A1

公开(公告)日：2014-10-02

申请号：US14113345

申请日：2012-06-27

Applicant: Hong Jin Kim ,  Bong Jo Kwak ,  Geun Sik Kang

Inventor： Hong Jin Kim ,  Bong Jo Kwak ,  Geun Sik Kang

IPC: G06F19/00 ,  A61B5/00

CPC classification number: A61B5/0022 ,  A61B5/7264 ,  A61B5/742 ,  G06F19/3418 ,  G06Q10/063114 ,  G06Q10/06315 ,  G06Q50/22 ,  G16H50/20

Abstract: A disease management system and method that use a wired and wireless communication network, in which motivation and consistent encouragement to change a behavior of a user or a patient may be given by close acquaintances or other people who have knowledge about a corresponding disease, instead of an expert. Thus, with regard to disease management that consistently needs normal and frequent communication, a role of an expert may be minimized to a necessary degree, and a more effective and efficient health care service, compared to a conventional health care service, may be provided.

Abstract translation: 使用有线和无线通信网络的疾病管理系统和方法，其中激励和一致的鼓励来改变用户或患者的行为可以由熟悉的熟人或具有相关疾病知识的其他人给出，而不是 专家。 因此，对于一贯需要正常和频繁沟通的疾病管理，可以将专家的作用尽可能地减至一定程度，并且可以提供与常规保健服务相比更有效和更有效的保健服务。

公开(公告)号：US08597081B2

公开(公告)日：2013-12-03

申请号：US13241421

申请日：2011-09-23

Applicant: Jae-Kwang Choi ,  Hong-Jin Kim ,  Keon-Sik Seo ,  Sol Han ,  Kun-Tack Lee ,  Byoung-Ho Kwon

Inventor： Jae-Kwang Choi ,  Hong-Jin Kim ,  Keon-Sik Seo ,  Sol Han ,  Kun-Tack Lee ,  Byoung-Ho Kwon

IPC: B24B1/00

CPC classification number: B24B53/017

Abstract: A pad conditioning disk, a pre-conditioning unit, and a CMP apparatus having the same are provided. The pad conditioning disk includes a base in which mountain-type tips and valley-type grooves are repeatedly connected to each other, and a cutting layer formed on the base layer. The cutting layer including conditioning particles deposited on surfaces of the tips and grooves. A surfaces roughness of conditioning particles deposited on the surfaces of the tips is less than a surface roughness of conditioning particles deposited on the surfaces of the grooves.

Abstract translation: 提供了衬垫调节盘，预调节单元和具有该调节盘的CMP设备。 垫调节盘包括其中山型尖端和谷型沟槽彼此重复连接的基底和形成在基底层上的切割层。 切割层包括沉积在尖端和凹槽表面上的调节颗粒。 沉积在尖端表面上的调理颗粒的表面粗糙度小于沉积在凹槽表面上的调理颗粒的表面粗糙度。

公开(公告)号：US20120100169A1

公开(公告)日：2012-04-26

申请号：US13379212

申请日：2009-10-20

Applicant: Hong-Jin Kim ,  Na Gyong Lee ,  Yang-Je Cho ,  Jin-Wook Jang ,  Hyoung Jin Kim ,  Kwang Sung Kim

Inventor： Hong-Jin Kim ,  Na Gyong Lee ,  Yang-Je Cho ,  Jin-Wook Jang ,  Hyoung Jin Kim ,  Kwang Sung Kim

IPC: A61K39/12 ,  A61P35/00 ,  C12N1/19 ,  A61P37/04 ,  C12P21/02 ,  C12N15/37

CPC classification number: A61K39/12 ,  A61K39/39 ,  A61K2039/5258 ,  A61K2039/55505 ,  A61K2039/55572 ,  A61K2039/70 ,  C12N2710/20023 ,  C12N2710/20034

Abstract: The present invention relates to a pharmaceutical vaccine composition for a human cervical cancer, comprising: (a) (i) a L1 virus-like particle (VLP) of human papillomavirus (HPV) type 16, a L1 VLP of HPV type 18, or a combination thereof; and (ii) a deacylated non-toxic lipooligosaccharide (LOS); and (b) a pharmaceutically acceptable carrier; and a method for preparing a human papillomavirus (HPV) L1 virus-like particle (VLP). The pharmaceutical vaccine composition of the present invention is in both Th1-type immune response (cellular immunity) and Th2-type immune response (humoral immunity) against HPV more excellent than Cervrix™ and Gardasil™, exhibiting a superior efficacy as a vaccine for a human cervical cancer.

Abstract translation: 本发明涉及用于人宫颈癌的药物疫苗组合物，其包括：（i）（i）16型人乳头状瘤病毒（HPV）的L1病毒样颗粒（VLP），HPV 18型的L1 VLP或 其组合; 和（ii）脱酰无毒低密度寡糖（LOS）; 和（b）药学上可接受的载体; 以及制备人乳头状瘤病毒（HPV）L1病毒样颗粒（VLP）的方法。 本发明的药物疫苗组合物具有比Cervrix TM和Gardasil TM更优异的Th1型免疫应答（细胞免疫）和对HPV的Th2型免疫应答（体液免疫），表现出作为疫苗的优异功效 人宫颈癌。

公开(公告)号：US20110032691A1

公开(公告)日：2011-02-10

申请号：US12839681

申请日：2010-07-20

Applicant: Hong-jin KIM ,  Young-ki SHON ,  Jae-wook JUNG

Inventor： Hong-jin KIM ,  Young-ki SHON ,  Jae-wook JUNG

IPC: H05K9/00 ,  H05K7/00

CPC classification number: H05K9/0054

Abstract: A plasma display apparatus having a structure of a base chassis to reduce EMI emission is provided. The plasma display apparatus includes a panel, a driving circuit, and a base chassis having at least one slit formed thereon.

Abstract translation: 提供具有用于减少EMI发射的基底结构的等离子体显示装置。 等离子体显示装置包括具有形成在其上的至少一个狭缝的面板，驱动电路和底架。

公开(公告)号：US20110031883A1

公开(公告)日：2011-02-10

申请号：US12839446

申请日：2010-07-20

Applicant: Hong-jin KIM ,  Young-ki SHON ,  Jae-wook JUNG

Inventor： Hong-jin KIM ,  Young-ki SHON ,  Jae-wook JUNG

IPC: H01J7/44

CPC classification number: H05K7/20963 ,  H05K9/0054

Abstract: A plasma display apparatus having a coupling structure between a base chassis and a spread sheet to reduce EMI emission is provided. The plasma display apparatus includes a panel, a driving circuit, a base chassis, a spread sheet, and a conductive gasket through which the spread sheet is coupled to the base chassis.

Abstract translation: 提供了一种等离子体显示装置，其具有底架和扩展片之间的耦合结构，以减少EMI发射。 等离子体显示装置包括面板，驱动电路，底架，展开片和导电垫片，通过该导电垫片将展开片材联接到底架。

公开(公告)号：US07626673B2

公开(公告)日：2009-12-01

申请号：US12289337

申请日：2008-10-24

Applicant: Hong Jin Kim

Inventor： Hong Jin Kim

IPC: G02F1/1343 ,  G02F1/1345

CPC classification number: G02F1/13458 ,  G02F1/1345

Abstract: A liquid crystal display having an electrode pad for compensating for differences in resistance of electrode links. A pad portion in contact with a driving circuit includes a transparent electrode pattern having a length that depends on the length of an associated electrode link that is connected between the pad portion and a corresponding signal line at a pixel area on which a plurality of liquid crystal cells are arranged. Accordingly, resistance differences that depend on the length of the electrode links are compensated for using electrode pads, thereby making signal conductors with substantially equal resistances.

公开(公告)号：US20090126607A1

公开(公告)日：2009-05-21

申请号：US12199878

申请日：2008-08-28

Applicant: Hong Jin Kim

Inventor： Hong Jin Kim

IPC: F23K3/00 ,  F23L1/00 ,  F23J1/02

CPC classification number: F23B40/04 ,  F23G5/165 ,  F23G5/24 ,  F23G5/46 ,  F23G2205/121 ,  F23K3/14 ,  F23L1/00 ,  F23L9/00

Abstract: A combustion apparatus for recovering heat according to the present invention comprising a combustion tank for burning fuel contained in the interior by combustion air supplied from the exterior, characterized in that: a combustion chamber surrounded by an inner wall for burning fuel is defined in said combustion tank; a swirl flow supply chamber for supplying a combustion air into said combustion chamber is defined around the outer circumference of the inner wall of said combustion tank; a combustion air supply passage for supplying combustion air from said swirl flow supply chamber into said combustion chamber is defined on the inner wall of said combustion tank; said combustion air supply passage is slanted at a predetermined angle to the vertical direction of the inner face of the inner wall in said combustion tank; and the combustion air generates a swirl flow in the combustion chamber. Furthermore, the combustion apparatus for recovering heat according to the invention characterized in that; an air cooling chamber for supplying combustion air supplied from the exterior into said swirl flow supply chamber is defined around the outer circumference of said swirl flow supply chamber in said combustion tank, and the combustion air supplied from the exterior is supplied through said cooling chamber into the swirl flow supply chamber to decrease a heat loss and to improve a thermal efficiency.

Abstract translation: 根据本发明的用于回收热量的燃烧装置，包括用于燃烧包含在内部的燃料的燃烧罐，其由从外部供应的燃烧空气燃烧，其特征在于：在所述燃烧中限定由燃烧燃料的内壁围绕的燃烧室 坦克; 围绕所述燃烧罐的内壁的外周限定用于将燃烧空气供给到所述燃烧室中的涡流供给室; 用于将燃烧空气从所述涡流供应室供给到所述燃烧室中的燃烧空气供给通道限定在所述燃烧罐的内壁上; 所述燃烧空气供给通道相对于所述燃烧罐内壁的内表面的垂直方向倾斜预定角度; 并且燃烧空气在燃烧室中产生涡流。 此外，根据本发明的用于回收热量的燃烧装置，其特征在于： 在所述燃烧罐中的所述涡流供给室的外周围形成有用于将从外部供给的燃烧空气供给到所述涡流供给室的空气冷却室，并且从外部供给的燃烧空气通过所述冷却室供给到 涡流供应室以减少热损失并提高热效率。

公开(公告)号：US07271669B2

公开(公告)日：2007-09-18

申请号：US10998964

申请日：2004-11-30

Applicant: Hong Jin Kim

Inventor： Hong Jin Kim

IPC: H03B1/00

CPC classification number: H03L7/0995

Abstract: A voltage controlled oscillator and a phase locked loop circuit having the same reduce power consumption by using charges leaked into a ground voltage terminal for an output driving operation with characteristics of both output terminals having different phases in a unit delay cell. The voltage controlled oscillator includes a plurality of unit delay cells connected serially. Each unit delay cell comprises a differential amplification unit and an output driving unit. The differential amplification unit compares a plurality of input voltages having different phases and amplifies the comparison result. The output driving unit, which is connected to both output terminals of the differential amplification units, drives an output voltage of another output terminal with a potential of one of both output terminals.

Abstract translation: 压控振荡器和锁相环电路具有相同的功率消耗，通过使用泄漏到接地电压端子的电荷来进行输出驱动操作，具有在单位延迟单元中具有不同相位的两个输出端子的特性。 压控振荡器包括串联连接的多个单元延迟单元。 每个单元延迟单元包括差分放大单元和输出驱动单元。 差分放大单元比较具有不同相位的多个输入电压并放大比较结果。 连接到差分放大单元的两个输出端的输出驱动单元以两个输出端之一的电位驱动另一输出端的输出电压。