Stable liquid antimicrobial suspension compositions containing quarternaries prepared from hexamethylenetetramine and certain halohydrocarbons
    2.
    发明授权
    Stable liquid antimicrobial suspension compositions containing quarternaries prepared from hexamethylenetetramine and certain halohydrocarbons 失效
    稳定的液体抗微生物悬浮液组合物含有由六亚甲基四胺和某些卤代烃制备的季铵盐

    公开(公告)号:US06576633B1

    公开(公告)日:2003-06-10

    申请号:US08603846

    申请日:1996-02-22

    IPC分类号: A01N4390

    CPC分类号: A01N43/90 A01N2300/00

    摘要: Anhydrous, liquid antimicrobial compositions comprising quaternaries 1-(benzyl)-3,5,7-triaza-1-azoniaadamantane chloride, 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride and the cis- and cis/trans-isomers thereof, 1-(&agr;-(2-xylyl))-3,5,7-triaza-1-azoniaadamantane chloride and methyl 1-(3,5,7-triaza-1-azoniaadamantane chloride) acetate in admixture with an anhydrous carrier liquid and a thixotropic material are substantially stable to color changes, physical changes and/or chemical changes while under conventional storage conditions for extended time periods.

    摘要翻译: 无水液体抗菌组合物,其包含季铵盐1-(苄基)-3,5,7-三氮杂-1-氮鎓金刚烷氯化物,1-(3-氯烯丙基)-3,5,7-三氮杂-1-氮鎓金刚烷氯化物和顺式 - 和其顺式/反式异构体,1-(α-(2-二甲苯基))-3,5,7-三氮杂-1-氮鎓金刚烷氯化物和1-(3,5,7-三氮杂-1-氮鎓金刚烷氯化物) 与无水载体液体和触变材料混合的乙酸酯在常规储存条件下延长的时间段内对颜色变化,物理变化和/或化学变化基本稳定。

    Periodic antimicrobial peptides
    3.
    发明授权
    Periodic antimicrobial peptides 失效
    定期抗菌肽

    公开(公告)号:US07091185B2

    公开(公告)日:2006-08-15

    申请号:US10785210

    申请日:2004-02-24

    IPC分类号: A61K38/00 C07K7/00

    摘要: One embodiment of the invention comprises a method of producing periodic peptides, which can have antimicrobial uses, and further comprises the peptides themselves. A preferred method comprises the synthesis of simple periodic peptides made from polymerizing identical monomer units of four or fewer amino acids, wherein the minimum length of active peptide is 15 or 16 residues and wherein the minimum percentage of cationic residues is at least 25%.

    摘要翻译: 本发明的一个实施方案包括产生可具有抗微生物用途的周期肽的方法,并且还包含肽本身。 优选的方法包括合成通过聚合四个或更少氨基酸的相同单体单元制备的简单周期肽,其中活性肽的最小长度为15或16个残基,其中阳离子残基的最小百分比为至少25%。

    IMPROVED BARRIER LAYER
    6.
    发明申请
    IMPROVED BARRIER LAYER 审中-公开
    改进障碍层

    公开(公告)号:US20110159308A1

    公开(公告)日:2011-06-30

    申请号:US12998036

    申请日:2009-09-11

    IPC分类号: B32B27/30 C09D139/02

    摘要: Disclosed herein is a barrier layer comprising a polyvinyl amine-polyvinyl alcohol copolymer applied to a substrate as a water-soluble composition, wherein the polyvinyl amine-polyvinyl alcohol copolymer is formed by copolymerizing: (a) from 99 to 1 mol % of N-vinylformamide and (b) from 1 to 99 mol % of one or more vinyl Ci-Ci0 alkyl esters, and then hydrolyzing from 30 to 100 mol % of the formyl groups from the copolymerized units (a) to form amino groups and from 30 to 100 mol % of the Cj-Cio alkyl ester groups from the copolymerized units (b) to form hydroxyl groups, wherein the copolymer has a unimodal compositional distribution as evidenced by essentially one peak in a gel permeation gradient elution chromatographic analysis. A method of producing a barrier layer is also disclosed.

    摘要翻译: 本文公开了包含作为水溶性组合物施用于基材的聚乙烯胺 - 聚乙烯醇共聚物的阻隔层,其中所述聚乙烯胺 - 聚乙烯醇共聚物通过共聚合形成:(a)99至1mol%的N- 乙烯基甲酰胺和(b)1至99摩尔%的一种或多种乙烯基C 1 -C 10烷基酯,然后从共聚单元(a)中将30至100摩尔%的甲酰基水解形成氨基,并从30至 100摩尔%的共聚单元(b)中的C 1 -C 10烷基酯基团形成羟基,其中共聚物具有单峰组成分布,如凝胶渗透梯度洗脱色谱分析中基本上一个峰所证明的。 还公开了制造阻挡层的方法。