公开(公告)号：US20120028917A1

公开(公告)日：2012-02-02

申请号：US12878539

申请日：2010-09-09

申请人： Marc PAYTON ,  Richard KENDALL

发明人： Marc PAYTON ,  Richard KENDALL

IPC分类号： A61K31/704 ,  A61P35/00 ,  A61K31/506

CPC分类号： A61K31/502

摘要： The present invention relates to methods of using the compound, N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl) -1-phthalazinamine, to treat cancers, including solid tumors, which have become resistant to treatment with chemotherapeutic agents, including anti-mitotic agents such as taxanes, and/or other anti-cancer agents, including aurora kinase inhibiting agents. The invention also includes methods of treating cancers refractory to such treatments by administering a pharmaceutical composition, comprising the compound to a cancer subject.

摘要翻译： 本发明涉及使用化合物N-（4 - （（3-（2-氨基-4-嘧啶基）-2-吡啶基）氧基）苯基）-4-（4-甲基-2-噻吩基） 1-酞嗪胺治疗已经变得对化学治疗剂（包括抗有丝分裂剂如紫杉烷类）和/或其它抗癌剂（包括极光激酶抑制剂）的治疗具有抗性的癌症，包括实体瘤。 本发明还包括通过向癌症受试者施用包含该化合物的药物组合物来治疗对这种治疗难治的癌症的方法。

公开(公告)号：US06408938B1

公开(公告)日：2002-06-25

申请号：US09051735

申请日：1998-04-20

申请人： Alan Gray ,  Richard Kendall Bolingbroke ,  John Michael Evans

发明人： Alan Gray ,  Richard Kendall Bolingbroke ,  John Michael Evans

IPC分类号： F28F1318

摘要： An aluminum alloy containing (in wt. %): 0.2-0.5 Fe; 0.7-1.2 Si; 1.2-1.6 Mn; up to 0.3 Mg; up to 0.5 Cu; up to 0.2 Zn; up to 0.1 Ti is used to make the fins of heat exchangers particularly car radiators. The finstock has high post braze strength and thermal conductivity, and has a sufficiently electronegative potential as to be capable of acting as a sacrificial anode for the heat exchanger tubes. By virtue of the absence of Sn, In, and Cr, these heat exchangers can be scrapped and melted for re-use.

公开(公告)号：US20100213455A1

公开(公告)日：2010-08-26

申请号：US12738471

申请日：2008-09-19

申请人： Mark James ,  Iain McCulloch ,  Warren Duffy ,  Philip Edward May ,  Dan Walker ,  David P. Waller ,  Richard Kendall Childers ,  Sheila E. Rodman

发明人： Mark James ,  Iain McCulloch ,  Warren Duffy ,  Philip Edward May ,  Dan Walker ,  David P. Waller ,  Richard Kendall Childers ,  Sheila E. Rodman

IPC分类号： H01L51/30 ,  H01L51/40 ,  H01L51/05 ,  H01B1/12 ,  H01B1/04 ,  H01L51/42 ,  H01L51/50 ,  H01L51/48 ,  H01L51/56

CPC分类号： H01L51/0003 ,  B82Y10/00 ,  C09D11/52 ,  H01B1/122 ,  H01G11/48 ,  H01L51/0036 ,  H01L51/0046 ,  Y02E10/549 ,  Y02E60/13

摘要： The invention relates to novel formulations comprising an organic semiconductor (OSC) and a conductive additive, to their use as conducting inks for the preparation of organic electronic (OE) devices, especially organic photovoltaic (OPV) cells, to methods for preparing OE devices using the novel formulations, and to OE devices and OPV cells prepared from such methods and formulations.

摘要翻译： 本发明涉及包含有机半导体（OSC）和导电添加剂的新配方，用于制备有机电子（OE）器件，特别是有机光伏（OPV）电池）的导电油墨用于制备OE器件的方法 新制剂，以及由这些方法和制剂制备的OE装置和OPV细胞。

公开(公告)号：US20090304694A1

公开(公告)日：2009-12-10

申请号：US12223003

申请日：2007-01-19

申请人： Jonathan Oliner ,  Richard Kendall ,  Rakesh Kumar

发明人： Jonathan Oliner ,  Richard Kendall ,  Rakesh Kumar

IPC分类号： A61K39/395 ,  A61P35/00

CPC分类号： A61K31/435 ,  A61K38/16 ,  A61K45/06 ,  A61K2300/00

摘要： The invention provides methods for using Ang2 inhibitors in combination with VEGF inhibitors to treat disease. The invention also provides compositions, kits, formulations, and specific disease treatments relating thereto.

摘要翻译： 本发明提供了使用Ang2抑制剂与VEGF抑制剂组合治疗疾病的方法。 本发明还提供了与其有关的组合物，试剂盒，制剂和特定疾病治疗。

公开(公告)号：US07036022B1

公开(公告)日：2006-04-25

申请号：US09515384

申请日：2000-02-29

申请人： Mary Ellen Zurko ,  Thomas Andrew Casey, Jr. ,  Morrie Gasser ,  Judith Shelhorse Hall ,  Clifford Earl Kahn ,  Andrew Halstead Mason ,  Paul Douglas Sawyer ,  Leslie Richard Kendall ,  Steven B. Lipner

发明人： Mary Ellen Zurko ,  Thomas Andrew Casey, Jr. ,  Morrie Gasser ,  Judith Shelhorse Hall ,  Clifford Earl Kahn ,  Andrew Halstead Mason ,  Paul Douglas Sawyer ,  Leslie Richard Kendall ,  Steven B. Lipner

IPC分类号： H04L9/32

CPC分类号： G06F21/53 ,  G06F2211/009

摘要： A method for executing trusted commands, in which a trusted command is first received from a user at a user terminal and parsed by untrusted code; then passed to a trusted computing base for execution. The trusted computing base displays some indication of what is to be done back to the user for confirmation. Confirmation of the commands prevents unauthorized modification of the commands and increases system confidence. A randomly (or pseudo-randomly) generated process identifier is employed to verify the existence of a trusted path.

摘要翻译： 一种用于执行可信命令的方法，其中首先从用户终端从用户接收到可信命令并由不受信任的代码解析; 然后传递到可信赖的计算基础执行。 可信计算基地向用户显示将要做什么的一些指示以供确认。 确认命令可防止未经授权的修改命令并增加系统的置信度。 随机（或伪随机）生成的进程标识符用于验证可信路径的存在。

公开(公告)号：US20060078459A1

公开(公告)日：2006-04-13

申请号：US10962962

申请日：2004-10-12

申请人： James Kohler ,  Szu-Min Lin ,  Richard Kendall

发明人： James Kohler ,  Szu-Min Lin ,  Richard Kendall

IPC分类号： A61L2/20

CPC分类号： A61L2/208 ,  A61L2/24 ,  A61L2202/122

摘要： A chemical vapor sterilization process is enhanced by concentrating a germicide via exploitation of the difference between the vapor pressures of the germicide and its solvent. A diffusion restriction can be placed into the diffusion path to assist this process and the path then opened to provide rapid diffusion of the thus concentrated germicide. The path through the diffusion restriction can be closed to allow the pressure in a sterilization chamber to be lowered prior to receiving the concentrated germicide.

公开(公告)号：US20060100638A1

公开(公告)日：2006-05-11

申请号：US10975211

申请日：2004-10-29

申请人： Vineet Sarin ,  William Pratt ,  Kyle Pilgeram ,  Richard Kendall

发明人： Vineet Sarin ,  William Pratt ,  Kyle Pilgeram ,  Richard Kendall

IPC分类号： A61B17/60

CPC分类号： A61B90/36 ,  A61B17/1778 ,  A61B34/20 ,  A61B2034/2055 ,  A61B2090/3916 ,  A61B2090/3983

摘要： The invention includes a method for tracking the human scapula during shoulder surgery, by a trackable device fixed to the coracoid process of the scapula. A device of the invention allows a trackable target to be fixed to the coracoid process by bone screws and an anchor. In one embodiment, a releasable coupling is provided between the anchor and the trackable target.

公开(公告)号：US06438737B1

公开(公告)日：2002-08-20

申请号：US09505059

申请日：2000-02-15

申请人： John Morelli ,  H. Richard Kendall

发明人： John Morelli ,  H. Richard Kendall

IPC分类号： G06F1750

CPC分类号： G06F15/7867

摘要： A system is disclosed including a reconfigurable logic circuit having programmable logic, a first memory, and a second memory. The first memory stores a number of logic designs each operable to configure the programmable logic. Also included is a computer coupled to the reconfigurable logic circuit that concurrently executes one or more application programs and an interface program. The application programs generate a number of requests to utilize the reconfigurable logic circuit and the interface program responds to the requests by opening a number of coexisting program interfaces. These interfaces each correspond to an instance of one of the logic designs stored in the first memory. The reconfigurable logic circuit is responsive to the interface program to provide a number of interface buffers in the second memory that each belong to a corresponding one of the interfaces and are each operable to store data passing between the computer and the reconfigurable logic circuit.

摘要翻译： 公开了一种包括具有可编程逻辑的可重构逻辑电路，第一存储器和第二存储器的系统。 第一存储器存储多个可用于配置可编程逻辑的逻辑设计。 还包括耦合到可重配置逻辑电路的计算机，其同时执行一个或多个应用程序和接口程序。 应用程序产生许多请求以利用可重构逻辑电路，并且接口程序通过打开多个共存程序接口来响应请求。 这些接口各自对应于存储在第一存储器中的逻辑设计之一的实例。 可重构逻辑电路响应于接口程序以在第二存储器中提供多个接口缓冲器，每个接口缓冲器各自属于对应的一个接口，并且每个可操作以存储在计算机和可重配置逻辑电路之间通过的数据。

公开(公告)号：USD416791S

公开(公告)日：1999-11-23

申请号：US89588

申请日：1998-06-18

申请人： Sandra Albrecht ,  Richard Kendall ,  Terry Gill

设计人： Sandra Albrecht ,  Richard Kendall ,  Terry Gill

公开(公告)号：US08748186B2

公开(公告)日：2014-06-10

申请号：US12644410

申请日：2009-12-22

申请人： Richard Kendall ,  John W. Roche

发明人： Richard Kendall ,  John W. Roche

IPC分类号： G01N33/72

CPC分类号： G01N15/1434 ,  G01N1/2813 ,  G01N15/1475 ,  G01N21/27 ,  G01N21/49 ,  G01N21/59 ,  G01N33/721 ,  G01N2001/282 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1486 ,  G01N2333/805

摘要： A method for counting blood cells in a sample of whole blood. The method comprises the steps of: (a) providing a sample of whole blood; (b) depositing the sample of whole blood onto a slide, e.g., a microscope slide; (c) employing a spreader to create a blood smear; (d) allowing the blood smear to dry on the slide; (e) measuring absorption or reflectance of light attributable to the hemoglobin in the red blood cells in the blood smear on the slide; (f) recording a magnified two-dimensional digital image of the area of analysis identified by the measurement in step (e) as being of suitable thickness for analysis; and (g) collecting, analyzing, and storing data from the magnified two-dimensional digital image. Optionally, steps of fixing and staining of blood cells on the slide can be employed in the method.

摘要翻译： 一种全血样品中血细胞计数的方法。 该方法包括以下步骤：（a）提供全血样品; （b）将全血样品沉积在载玻片上，例如显微镜载片上; （c）使用吊具产生血液涂片; （d）允许血液涂片在载玻片上干燥; （e）测量归因于载玻片上血液涂片中红细胞中血红蛋白的光的吸光度或反射率; （f）将通过步骤（e）中的测量识别的分析区域的放大二维数字图像记录为具有适于分析的厚度; 和（g）从放大的二维数字图像中收集，分析和存储数据。 任选地，可以在该方法中使用在载玻片上固定和染色血细胞的步骤。