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    PFO closure devices and related methods of use
    4.
    发明授权
    PFO closure devices and related methods of use 有权
    PFO封闭装置及相关使用方法

    公开(公告)号：US07976564B2

    公开(公告)日：2011-07-12

    申请号：US10138565

    申请日：2002-05-06

    申请人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

    发明人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, Jr. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

    IPC分类号： A61B17/08

    CPC分类号： A61B17/0469 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0409 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0496 ,  A61B2017/22051

    摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

    摘要翻译： 提供用于密封由心脏中的卵圆孔卵孔（PFO轨迹）形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起，或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后，释放压力，磨损的组织愈合，在PFO轨迹上形成牢固的密封。 另外，提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中，也可能不会留在PFO轨道中。 如果设备不在PFO轨道内，PFO轨道的墙壁被粘合剂覆盖，彼此并置并粘合在一起。 如果设备留在PFO轨道内，则设备将从扩展配置平坦化到平坦的配置，并且随着设备平坦化，PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

    PFO CLOSURE DEVICES AND RELATED METHODS OF USE
    6.
    发明申请
    PFO CLOSURE DEVICES AND RELATED METHODS OF USE 审中-公开
    PFO封闭装置及相关使用方法

    公开(公告)号：US20100234881A1

    公开(公告)日：2010-09-16

    申请号：US12725886

    申请日：2010-03-17

    申请人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, JR. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

    发明人： David J. Blaeser ,  Peter T. Keith ,  Jerome K. Grudem, JR. ,  Scott A. Olson ,  Steven S. Hackett ,  Thomas V. Ressemann ,  Joel D. Phillips ,  Mark R. Christianson ,  Dennis W. Wahr

    IPC分类号： A61B17/03

    CPC分类号： A61B17/0469 ,  A61B17/00491 ,  A61B17/0057 ,  A61B17/0401 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/0409 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/0474 ,  A61B2017/0496 ,  A61B2017/22051

    摘要： Devices and methods for sealing a passageway formed by a patent foramen ovale (PFO track) in the heart are provided. One method includes providing an abrading device to the PFO track and abrading the tissue within the PFO track. The abraded tissue forming the PFO track is then held together under pressure, either via lowering right atrial pressure or via applying suction to the septum primum to pull it into apposition against the septum secundum. After a sufficient period of time, the pressure is released and the abraded tissue heals to form a robust seal over the PFO track. Additionally, several devices are provided which can be placed into the PFO track to apply adhesive to the walls of the PFO track. The devices may or may not be left within the PFO track. If the devices are not left within the PFO track, the walls of the PFO track, covered with adhesive, are brought into apposition with one another and adhered together. If the device is left within the PFO track, the device is flattened from an expanded configuration to a flattened configuration, and the walls of the PFO track, adhering to the outer surface of the device, are pulled toward each other as the device flattens. The device may also include interior structure to hold the device in a flattened configuration.

    摘要翻译： 提供用于密封由心脏中的卵圆孔卵孔（PFO轨迹）形成的通道的装置和方法。 一种方法包括向PFO轨道提供研磨装置并研磨PFO轨道内的组织。 形成PFO轨道的磨损组织然后在压力下保持在一起，或者通过降低右心房压力或通过向隔膜施加抽吸使其与隔膜隔层相对。 经过足够的时间后，释放压力，磨损的组织愈合，在PFO轨迹上形成牢固的密封。 另外，提供了可以放置到PFO轨道中以将粘合剂施加到PFO轨道的壁上的几个装置。 设备可能会留在PFO轨道中，也可能不会留在PFO轨道中。 如果设备不在PFO轨道内，PFO轨道的墙壁被粘合剂覆盖，彼此并置并粘合在一起。 如果设备留在PFO轨道内，则设备将从扩展配置平坦化到平坦的配置，并且随着设备平坦化，PFO轨道的粘附在设备外表面上的墙壁会相互拉紧。 该装置还可以包括用于将装置保持在扁平结构中的内部结构。

    EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE
    7.
    发明申请
    EMBOLI PROTECTION DEVICES AND RELATED METHODS OF USE 审中-公开
    EMBOLI保护装置及相关使用方法

    公开(公告)号：US20080243171A1

    公开(公告)日：2008-10-02

    申请号：US12123374

    申请日：2008-05-19

    申请人： THOMAS V. RESSEMANN ,  Steven S. Hackett ,  Andrew J. Dusbabek ,  Scott A. Olson ,  Peter T. Keith ,  Dennis W. Wahr

    发明人： THOMAS V. RESSEMANN ,  Steven S. Hackett ,  Andrew J. Dusbabek ,  Scott A. Olson ,  Peter T. Keith ,  Dennis W. Wahr

    IPC分类号： A61M29/00

    CPC分类号： A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/22 ,  A61B90/39 ,  A61B2017/12127 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61B2017/22084 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2/95

    摘要： An embolic protection system for treating a lesion in a blood vessel is provided. The embolic protection system includes a guide catheter, an evacuation sheath, a guidewire, and an infusion catheter. The guide catheter has a guidewire lumen. The evacuation sheath has an evacuation lumen and a sealing surface and is configured to move within the lumen of the guide catheter. The guidewire is configured to move within the lumen of the guide catheter and the evacuation lumen. The infusion catheter has an infusion lumen, at least one infusion port, and a guidewire lumen configured to accept the guidewire, the infusion catheter guidewire lumen being shorter than the guide catheter guidewire lumen. Furthermore, the infusion catheter is configured to move within the lumen of the guide catheter and the evacuation lumen over the guidewire. The system may further comprise a dilation catheter having a dilation balloon and a guidewire lumen.

    摘要翻译： 提供一种治疗血管病变的栓塞保护系统。 栓塞保护系统包括引导导管，抽真空鞘，导丝和输注导管。 引导导管具有导丝管腔。 抽真空鞘具有抽空腔和密封表面，并且构造成在导管的内腔内移动。 引导线被构造成在引导导管的内腔和排泄腔内移动。 输注导管具有输注腔，至少一个输注端口和构造成接纳导丝的导丝管腔，输液导管导丝管腔比引导导管导丝管腔更短。 此外，输注导管构造成在引导导管的内腔和引导线上的排空腔中移动。 该系统还可以包括具有扩张气囊和导丝管腔的扩张导管。

    System and Method for Arterial Access
    8.
    发明申请
    System and Method for Arterial Access 有权
    动脉通路系统与方法

    公开(公告)号：US20080154190A1

    公开(公告)日：2008-06-26

    申请号：US11848461

    申请日：2007-08-31

    申请人： Jon St. Germain ,  Scott A. Olson ,  Daniel J. Klima ,  John A. Roop ,  Paul J. Thompson

    发明人： Jon St. Germain ,  Scott A. Olson ,  Daniel J. Klima ,  John A. Roop ,  Paul J. Thompson

    IPC分类号： A61M25/092 ,  A61M25/09 ,  A61M25/00

    CPC分类号： A61M25/0136 ,  A61M25/0041 ,  A61M25/005 ,  A61M25/0053 ,  A61M25/0054

    摘要： A system for arterial access for delivery of treatment devices is provided. In one embodiment, the system comprises a guidewire and a catheter. The catheter comprises a handle and a shaft. The shaft may be a steerable/deflectable tip shaft with a lumen adapted to allow passage of the guidewire at least partially there through. A passive sheath may also be provided to be delivered over the shaft. The handle controls the steerable/deflectable tip shaft and may be used to deflect the distal tip of the shaft.

    摘要翻译： 提供了用于输送治疗装置的用于动脉通路的系统。 在一个实施例中，系统包括导丝和导管。 导管包括手柄和轴。 轴可以是可转向/可偏转的尖端轴，其具有适于允许导丝至少部分地通过导管的内腔。 也可以设置被动护套以在轴上传送。 手柄控制可转向/可偏转的尖端轴，并可用于偏转轴的远端。

    Emboli protection devices and related methods of use
    9.
    发明授权
    Emboli protection devices and related methods of use 有权
    Emboli保护装置及相关使用方法

    公开(公告)号：US07374560B2

    公开(公告)日：2008-05-20

    申请号：US09940986

    申请日：2001-08-29

    申请人： Thomas V Ressemann ,  Steven S Hackett ,  Andrew J Dusbabek ,  Scott A Olson ,  Peter T Keith ,  Dennis W Wahr

    发明人： Thomas V Ressemann ,  Steven S Hackett ,  Andrew J Dusbabek ,  Scott A Olson ,  Peter T Keith ,  Dennis W Wahr

    IPC分类号： A61M31/00

    CPC分类号： A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/22 ,  A61B90/39 ,  A61B2017/12127 ,  A61B2017/22067 ,  A61B2017/22079 ,  A61B2017/22082 ,  A61B2017/22084 ,  A61B2217/005 ,  A61B2217/007 ,  A61F2/95

    摘要： An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly. If necessary to increase retrograde flow, the coronary sinus may be at least partially occluded. Alternatively, antegrade flow may be permitted while flow is occluded at the treatment site.

    摘要翻译： 提供疏散鞘组件和治疗闭塞血管的方法，其减少血管干预期间远端栓塞的风险。 抽真空组件包括限定具有近端和远端的抽空腔的细长管。 近侧密封表面设置在管的近端部分上，并被构造成与引导导管的内腔形成密封。 远端密封表面设置在管的远端部分上并构造成与血管形成密封。 提供闭塞器组件和输注导管组件以与抽真空组件一起使用。 使用排气鞘组件治疗血管的方法包括通过引导导管将排空鞘组件推进到血管中。 停止接近狭窄的血管中的正常顺行血流，并治疗狭窄。 在血管内引起逆行血流，以便在处理进入抽真空鞘组件期间将栓塞物移走。 如果需要增加逆行流量，冠状窦可能至少部分闭塞。 或者，可以允许在治疗部位闭塞流动时顺行流动。

    Feedforward amplifier
    10.
    发明授权
    Feedforward amplifier 有权
    前馈放大器

    公开(公告)号：US06573792B1

    公开(公告)日：2003-06-03

    申请号：US10017984

    申请日：2001-12-13

    申请人： Scott A. Olson ,  Robert E. Stengel

    发明人： Scott A. Olson ,  Robert E. Stengel

    IPC分类号： H03F100

    CPC分类号： H03F1/3229

    摘要： A feedforward amplifier (150) according to the present invention uses a direct coupling of an amplifier stage (158) with the amplifier's load (RL). The main amplifier (202) is coupled through a transmission line (210) to the load. This direct coupled amplifier stage (158) is driven by a signal that induces a very low impedance in parallel with the load to the error signal, but appears as an open circuit to the desired signal so that the desired signal from the main amplifier is substantially unaffected.

    摘要翻译： 根据本发明的前馈放大器（150）使用放大器级（158）与放大器的负载（RL）的直接耦合。 主放大器（202）通过传输线（210）耦合到负载。 该直接耦合放大器级158由一个信号驱动，该信号引起与该误差信号的负载并联的非常低的阻抗，但是作为对所需信号的开路呈现，使得来自主放大器的所需信号基本上 不受影响