Non-aqueous patch
    1.
    发明授权

    公开(公告)号:US10765640B2

    公开(公告)日:2020-09-08

    申请号:US14346794

    申请日:2011-09-27

    IPC分类号: A61K9/70 A61K31/167

    摘要: [Problem]If lidocaine is composed of non-aqueous patch, the adhesive power of the preparation tends to get lower, as the composition amount of lidocaine is higher. It is popular to solve lidocaine in dissolving agent in order to compose lidocaine in patch and release effective amount into skin. However, if the amount of dissolving agent gets higher, the adhesive power gets extremely lower, so that an long-time attachment is difficult.[Solution]A non-aqueous patch comprising lidocaine and/or its reactant, and a dissolving agent which are contained in a base of plaster, the plaster being hold by a support, of which strength of 50% stretched to longitudinal direction is less than 2,000 g/50 mm and of biaxially-oriented stretch cloth.

    Non-aqueous patch
    2.
    发明授权
    Non-aqueous patch 有权
    非水补丁

    公开(公告)号:US09283174B2

    公开(公告)日:2016-03-15

    申请号:US14116730

    申请日:2011-05-10

    摘要: Non-aqueous patches comprising lidocaine, which is not dissolved and is present in a crystalline state, have poor permeability to the skin. Therefore, non-aqueous patches have a high concentration of lidocaine. It is pointed out that lidocaine has an adverse effect on the heart. Prolonged use of a high concentration of lidocaine causes side effects, such as shock, rubor, and irritating sensation. External preparations comprising more than 5 mass % of lidocaine are designated as powerful drugs, and cannot be used as household (nonprescription) medicine. Provided is a non-aqueous patch that is effective to relieve muscle pain, the non-aqueous patch comprising lidocaine and/or its reactant, and a dissolving agent composed of an organic acid and a polyalcohol, which are contained in a base.

    摘要翻译: 包含利多卡因的非水性贴剂,其不溶解并以结晶状态存在,对皮肤的渗透性差。 因此,非水性贴剂具有高浓度的利多卡因。 指出利多卡因对心脏有不良影响。 长时间使用高浓度的利多卡因会引起副作用,如休克,红酒和刺激感。 含有超过5质量%利多卡因的外用制剂被指定为强力药物,不能用作家庭(非处方)药物。 本发明提供了一种非水性贴剂,其有效地缓解肌肉疼痛,非水性贴剂包含利多卡因和/或其反应物,以及由有机酸和多元醇组成的溶解剂,其包含在基质中。

    Driving apparatus for multiplex-winding rotary machine
    4.
    发明授权
    Driving apparatus for multiplex-winding rotary machine 有权
    多功能旋转机驱动装置

    公开(公告)号:US08963462B2

    公开(公告)日:2015-02-24

    申请号:US13727020

    申请日:2012-12-26

    摘要: Provided are rotational position detection means detecting the rotational position of a multiplex-winding rotary machine; failure determination means determining failure of the rotational position detection means; control means calculating a voltage instruction for each winding group, based on the rotational position detected by the rotational position detection means; and voltage application means applying voltage to each winding group, based on the voltage instruction. According to the failure determination by the failure determination means, the control means outputs a voltage instruction for rotational position estimation to the voltage application means, and estimates the rotational position θe, based on at least one of voltage and current obtained from the winding group in accordance with the voltage instruction.

    摘要翻译: 提供了检测多路复卷机的旋转位置的旋转位置检测装置; 故障确定装置确定旋转位置检测装置的故障; 控制装置,基于由所述旋转位置检测装置检测到的旋转位置,计算每个卷绕组的电压指令; 并且电压施加装置基于电压指令向每个绕组组施加电压。 根据故障确定装置的故障确定,控制装置向电压施加装置输出用于旋转位置估计的电压指令,并且基于从绕组获得的电压和电流中的至少一个来估计旋转位置和电位; e, 组按照电压指令。

    Printing apparatus and printing method
    7.
    发明授权
    Printing apparatus and printing method 失效
    印刷装置和印刷方法

    公开(公告)号:US08465116B2

    公开(公告)日:2013-06-18

    申请号:US12851853

    申请日:2010-08-06

    IPC分类号: B41J29/38 B41J2/165

    CPC分类号: B41J29/40 B41J2/125 B41J29/38

    摘要: In a printing apparatus and a printing method, the frequency of an operation of detecting an inappropriate ejection state of each ejection port is increased, while allowing a decrease in throughput to be suppressed. The printing apparatus includes a first ejection state sensing unit for carrying out an ejection state sensing process in which determination of whether or not ejected droplets are normal is executed, during a single process, on all the ejection ports formed in the print head. The printing apparatus further includes a second ejection state sensing unit for carrying out the ejection state sensing process on the ejection ports in a part of a plurality of ejection port groups into which the plurality of ejection ports formed in the print head are divided.

    摘要翻译: 在打印装置和打印方法中,增加了检测每个喷射口的不适当喷射状态的操作的频率,同时允许抑制吞吐量的降低。 打印装置包括用于执行喷墨状态检测处理的第一喷射状态检测单元,其中在单个处理期间,在形成在打印头中的所有喷射口上执行喷射液滴是否正常的确定。 打印装置还包括第二喷射状态检测单元,用于对形成在打印头中的多个喷射口进行分割的多个喷射口组的一部分中的喷射口进行喷射状态检测处理。

    PROCESS FOR PREPARATION OF (Z)-CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID COMPOUNDS
    8.
    发明申请
    PROCESS FOR PREPARATION OF (Z)-CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID COMPOUNDS 审中-公开
    制备(Z) - 亚烷基环戊二烯羧酸的化合物的方法

    公开(公告)号:US20130006008A1

    公开(公告)日:2013-01-03

    申请号:US13508935

    申请日:2010-12-01

    IPC分类号: C07C253/30

    摘要: A method for producing a (Z)-cyanoalkenyl-cyclopropanecarboxylic acid compound, which includes the step of isomerizing an (E)-cyanoalkenyl-cyclopropanecarboxylic acid compound (1) into a (Z)-cyanoalkenyl-cyclopropanecarboxylic acid compound (2) in the presence of at least one isomerizing catalyst selected from the group consisting of bromine, hydrogen bromide, brominated carboxylic acids, brominated phosphorus compounds, N-brominated imide compounds, N-brominated amide compounds, brominated alkylsilane compounds, thionyl bromide, brominated boron compounds, brominated aluminum compounds, thiol compounds, disulfide compounds, thiocarboxylic acid compounds, nitric acid and nitrate salts: wherein R1 and R2 represent, R1 represents an alkyl group which may have a substituent, or a halogen atom, and R2 represents a hydrogen atom, an alkyl group which may have a substituent, or a benzyl group which may have a substituent.

    摘要翻译: (Z) - 氰基链烯基 - 环丙烷羧酸化合物的制造方法,其包括将(E) - 氰基链烯基 - 环丙烷羧酸化合物(1)异构化为(Z) - 氰基链烯基 - 环丙烷羧酸化合物(2) 存在至少一种异构化催化剂,其选自溴,溴化氢,溴化羧酸,溴化磷化合物,N-溴化酰亚胺化合物,N-溴化酰胺化合物,溴化烷基硅烷化合物,亚硫酰溴,溴化硼化合物,溴化 铝化合物,硫醇化合物,二硫化物,硫代羧酸化合物,硝酸和硝酸盐:其中R1和R2表示,R1表示可以具有取代基的烷基或卤素原子,R2表示氢原子,烷基 可以具有取代基的基团,或可以具有取代基的苄基。

    ELECTRIC-POWER CONVERSION APPARATUS
    9.
    发明申请
    ELECTRIC-POWER CONVERSION APPARATUS 有权
    电力转换装置

    公开(公告)号:US20120057381A1

    公开(公告)日:2012-03-08

    申请号:US13039841

    申请日:2011-03-03

    IPC分类号: H02M1/00

    摘要: There is provided an electric-power conversion apparatus including a chopper circuit; a current sense resistor that detects the output current of the chopper circuit; a differential detection circuit that outputs, as a differential detection signal (vo), the electric potential difference across the current sense resistor; and a calculation means that corrects the differential detection signal (vo) from the differential detection circuit by use of a control signal (D1) for the chopper circuit so as to calculate the output current (i0) of the chopper circuit.

    摘要翻译: 提供一种包括斩波电路的电力转换装置; 检测斩波电路的输出电流的电流检测电阻; 差分检测电路作为差分检测信​​号(vo)输出电流检测电阻器两端的电位差; 以及计算装置,通过使用用于斩波电路的控制信号(D1)来校正来自差分检测电路的差分检测信​​号(vo),以计算斩波电路的输出电流(i0)。

    PRINTING APPARATUS AND PRINTING METHOD
    10.
    发明申请
    PRINTING APPARATUS AND PRINTING METHOD 失效
    印刷装置和印刷方法

    公开(公告)号:US20100321431A1

    公开(公告)日:2010-12-23

    申请号:US12817240

    申请日:2010-06-17

    申请人: Tatsuya Mori

    发明人: Tatsuya Mori

    IPC分类号: B41J29/38

    摘要: A printing apparatus and a printing method in which an ejection failure state sensing process is sufficiently carried out while a decrease in printing throughput to be suppressed are provided. The print head includes at least two ejection ports through which different amounts of ink in the same color are ejected; both ejection amounts are equal to or smaller than 5 pl. The printing apparatus carries out a first ejection failure state sensing process for sensing a first ejection ports which have the smallest opening area in the ejection ports formed in the print head. The printing apparatus also carries out a second ejection failure state sensing process for sensing an ejection state in which ink is ejected through all the ejection ports in the print head. When any ejection port is determined to be in an inappropriate ejection state, the printing apparatus carries out compensation printing.

    摘要翻译: 提供了在要抑制的打印吞吐量降低的同时充分执行喷射故障状态感测处理的打印装置和打印方法。 打印头包括至少两个喷射口,通过该喷射口排出相同颜色的不同量的墨; 喷射量均等于或小于5pl。 打印装置执行用于感测在形成在打印头中的喷射口中具有最小开口面积的第一喷射口的第一喷射故障状态感测处理。 打印设备还执行第二喷射故障状态检测处理,用于感测喷射状态,其中通过打印头中的所有喷射口喷射墨水。 当确定喷墨口处于不适当的喷射状态时,打印设备进行补偿打印。