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公开(公告)号：US20240379229A1
公开(公告)日：2024-11-14
申请号：US18564601
申请日：2022-05-30
Applicant: GC GENOME CORPORATION , THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： CHANG-SEOK KI , EUN HAE CHO , JUNNAM LEE , JIN MO AHN , SOOK RYUN PARK
Abstract: The present invention relates to a method of diagnosing cancer and predicting cancer type using cell-free nucleic acid fragments and image analysis technology, and more particularly, to a method of diagnosing cancer and predicting cancer type by extracting nucleic acids from a biological sample to obtain sequence information (reads), aligning the obtained reads, generating an image including size and coverage information of nucleic acid fragments based on the aligned reads, and then analyzing values calculated by inputting the image into a trained artificial intelligence model. The method of diagnosing cancer and predicting cancer type using size and coverage information of cell-free nucleic acid fragments according to the present invention advantageously shows high sensitivity and accuracy because it generates vectorized data and performs analysis using an AI algorithm.
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公开(公告)号：US20240274276A1
公开(公告)日：2024-08-15
申请号：US18647161
申请日：2024-04-26
Applicant: Coreline Soft Co., Ltd. , THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： Sang Min LEE , Dong Hyun YANG , Jin Kook KIM , Jaeyoun YI , Donghoon YU , Seung Lee PARK
CPC classification number: G16H30/40 , G06F3/0482 , G06N3/08 , G06T7/0012 , G06T7/11 , G06T11/00 , G16H30/20 , G16H50/20 , G06T2200/24 , G06T2207/20081 , G06T2207/20084 , G06T2207/20092 , G06T2207/30061 , G06T2207/30096
Abstract: Disclosed is an apparatus for assisting the reading of a medical image based on a medical artificial neural network, the apparatus including a computing system. An apparatus according to an embodiment of the present invention includes a computing system, and the computing system includes at least one processor. The at least one processor acquires or receives a first analysis result obtained through the inference of a first artificial neural network for a first medical image, generates a first visualization format, which is a representative visualization format of the first medical image, based on the first analysis result, and visualizes the first medical image and the first analysis result based on the first visualization format.
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3.发明公开公开(公告)号：US20240197554A1
公开(公告)日：2024-06-20
申请号：US18590552
申请日：2024-02-28
Applicant: THE ASAN FOUNDATION , NUNAPS INC. , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
Inventor： Dong Wha KANG , Hyun Taek LIM , Byung Joo LEE , Rak Kyeun HONG , Yong Hwan KIM
CPC classification number: A61H5/005 , G06F3/013 , G06T7/0012 , G06T7/20 , G06T7/70 , G06T19/00 , A61H2201/0107 , A61H2201/5007 , A61H2201/5043 , G06T2207/30041
Abstract: The present invention relates to an apparatus and method for providing virtual reality-based eye movement exercise and visual perception training, wherein a dichoptic presentation is provided in consideration of the deviation of a user's eyeball so as to prevent additional damage to stereoscopic vision due to suppression, and is provided by adjusting the degree of difficulty by changing the locations of visual stimuli on the basis of the level of deviation and training capability of the user, thus making it possible for the user to not only receive training suitable for the user's condition, but also simultaneously undergo visual perception training including eye exercise (movement) training and stereoscopic perception recognition.
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公开(公告)号：US20240181053A1
公开(公告)日：2024-06-06
申请号：US18285135
申请日：2022-03-30
Applicant: NEOGENTC CORP. , THE ASAN FOUNDATION , University of Ulsan Foundation for Industry Cooperation
Inventor： Hee Jin LEE , Kyu Jin LEE , Hye Seon PARK , Gyung Yub GONG , Chae Lyul LIM , Young Ae KIM , Ji ll CHOI
IPC: A61K39/00 , A61P35/00 , C12N5/0783
CPC classification number: A61K39/4611 , A61P35/00 , C12N5/0636 , C12N2501/2302 , C12N2501/515 , C12N2502/11 , C12N2506/30
Abstract: A method for producing an immune cell composition is disclosed. The method includes steps of: (a) culturing a tumor sample in a first container, (b) obtaining a first immune cell population from the cultured product obtained from (a); (c) seeding a second composition and a second immune cell population in a second container; (d) expending the second immune cell population to produce a third immune cell population; and (e) obtaining the third immune cell population from the expanded product obtained from (d) and producing the immune cell composition.
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公开(公告)号：US20240175872A1
公开(公告)日：2024-05-30
申请号：US18552133
申请日：2022-03-21
Applicant: THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION , HUMANSCAPE INC.
Inventor： Chong Jai KIM , Kyung Gon KIM , Beom Hee LEE , Eun Na KIM , Min Hoo CHANG , Hwangkyo JEONG , Hyo-Sang DO
IPC: G01N33/574 , C12Q1/6886 , G01N33/50
CPC classification number: G01N33/57407 , C12Q1/6886 , G01N33/5011 , C12Q2600/136 , C12Q2600/158 , G01N2333/70596 , G01N2333/912 , G01N2333/96486
Abstract: The present invention relates to a composition for the differential diagnosis of malignant peripheral nerve sheath tumor (MPNST), a differential diagnosis kit comprising same, a method for providing information required for differential diagnosis of MPNST using same, a method for screening materials for preventing, alleviating, and treating MPNST, and the like. Using the composition capable of detecting the protein marker of the present invention has the effect of making it possible to predict and diagnose whether a malignant tumor has occurred in a patient with neurofibromatosis type 1.
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Patent Agency Ranking
公开(公告)号：US20240115624A1
公开(公告)日：2024-04-11
申请号：US18482063
申请日：2023-10-06
Inventor： Soo-Jong HONG
CPC classification number: A61K35/74 , A61K9/0056 , A61P17/00 , A61K2035/11
Abstract: A method for treating an inflammatory skin disease, including administering to a subject in need thereof a pharmaceutical composition containing Ruminococcus gnavus as an active ingredient. A method for treating an inflammatory skin disease, including applying to a subject in need thereof a cosmetic composition containing Ruminococcus gnavus as an active ingredient.
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7.发明公开公开(公告)号：US20240104725A1
公开(公告)日：2024-03-28
申请号：US18255800
申请日：2021-12-02
Inventor： Soo Jin KANG , June Goo LEE , Hyung Joo CHO , Hyun Seok MIN
IPC: G06T7/00
CPC classification number: G06T7/0012 , G06T2207/10132 , G06T2207/20081 , G06T2207/30101
Abstract: A method of analyzing a plaque tissue component based on deep learning, the method including: extracting a plurality of first intravascular ultrasound (IVUS) cross-sectional images into which a first IVUS image that is a preprocedural IVUS image of a patient is divided at predetermined intervals; labeling each of the plurality of first IVUS cross-sectional images by using label indices corresponding to plaque tissue components to form labeled images, performing image conversion to obtain a polar coordinate image through which a distribution of tissue components for each angle is identifiable by performing a coordinate transformation based on the labeled images, extracting a label vector for each angle based on the polar coordinate image, and outputting output data obtained by quantifying the tissue components for each angle by using an artificial intelligence model that is trained by using, as training data, the label vector for each angle.
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公开(公告)号：US20230390344A1
公开(公告)日：2023-12-07
申请号：US18250913
申请日：2021-10-27
Applicant: THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION , NATIONAL CANCER CENTER
Inventor： Sook Ryun PARK
Abstract: A method for enhancing immunity, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof to a subject in need thereof. A method for increasing an anticancer effect, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof to a subject in need thereof. A method for treating cancer, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof, and an immune checkpoint inhibitor to a subject in need thereof.
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9.发明授权公开(公告)号：US11819710B2
公开(公告)日：2023-11-21
申请号：US17110957
申请日：2020-12-03
Applicant: THE ASAN FOUNDATION , UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION , NATIONAL CANCER CENTER , THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY , KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
Inventor： Ho Jin Kim , Jung Won Kwak , Byung Chul Cho , Sang Wook Lee , Chi Young Jeong , Young Kyung Lim , Ui Jung Hwang , Sang Hyoun Choi
CPC classification number: A61N5/1031 , A61N5/1001 , A61N5/1064 , G06T11/008 , A61N2005/1034
Abstract: The present invention relates to a method, a device, and a program for calculating a brachytherapy plan, and a brachytherapy apparatus. The method comprises: a step in which a computer obtains the number of radiation irradiation spots on the basis of radiation irradiation information (a radiation irradiation spot number obtaining step (S200)); a step in which the computer obtains target area information from a body model of a patient generated on the basis of medical image data of the patient (a target area information obtaining step (S400)); and a therapy plan calculating step (S600) in which the computer calculates, on the basis of the radiation irradiation information and the target area information, the radiation irradiation spots to which radiation is irradiated and the time length of irradiation to each radiation irradiation spot.
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公开(公告)号：US11692160B2
公开(公告)日：2023-07-04
申请号：US16349217
申请日：2017-11-10
Inventor： Gi Seok Jeong , Changmo Hwang , Se-Jin Jang
IPC: C12M3/06 , B01L3/00 , C12M3/00 , C12M1/32 , C12M1/00 , C12M1/12 , C12N5/00 , C12N5/09 , C12Q1/02 , C12M1/26
CPC classification number: C12M23/16 , B01L3/502761 , C12M1/26 , C12M1/32 , C12M3/06 , C12M21/08 , C12M23/12 , C12M23/50 , C12M25/00 , C12N5/0062 , C12N5/0693 , C12Q1/025 , B01L2300/0864 , B01L2300/0874 , C12N2513/00
Abstract: The microfluidic chip according to an embodiment of the present invention may include a plate, a bridge channel formed in intaglio on one side of the plate, an inlet formed through the plate to communicate with one end of the bridge channel, an outlet formed through the plate to communicate with the other end of the bridge channel, and at least one well extending in an outward direction of the plate from the bridge channel to provide a space, wherein the bridge channel may be in the form of a curved line, a bent line, an arc, a circle, a spiral, or a polygon.
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