公开(公告)号：US20170239282A1

公开(公告)日：2017-08-24

申请号：US15589963

申请日：2017-05-08

Applicant: ACADEMIA SINICA

Inventor： Wen-Chin YANG ,  Lee-Tian CHANG

IPC: A61K31/7028 ,  A23K50/75 ,  A23K20/163 ,  A61K36/28 ,  A23K20/10

CPC classification number: A61K31/7028 ,  A23K10/30 ,  A23K20/00 ,  A23K20/10 ,  A23K20/163 ,  A23K20/195 ,  A23K50/70 ,  A23K50/75 ,  A23K50/80 ,  A23V2002/00 ,  A23V2200/32 ,  A61K36/00 ,  A61K36/28

Abstract: A composition for use in prevention, inhibition and/or treatment of coccidiosis in an animal is disclosed. The composition comprises an effective amount of Bidens pilosa, an active constituent thereof, or an active compound isolated therefrom. In another aspect, a composition for use in enhancing growth in an animal is disclosed. The composition comprising an animal feed and an effective amount of Bidens pilosa, or an isolated active constituent comprising a polyacetylenic compound.

公开(公告)号：US20230010294A1

公开(公告)日：2023-01-12

申请号：US17782595

申请日：2020-12-02

Applicant: ACADEMIA SINICA

Inventor： Wen-Chin YANG ,  Yang-Han LEE ,  Yu-Chuan LIANG ,  Frederick Kin Hing PHOA ,  Lee-Tian CHANG ,  Cheng-Chih HSU ,  Jia-Kun CHEN ,  Shau-Ping LIN ,  Chiao-LING HSIAO

IPC: A01K45/00 ,  A01K31/18 ,  A01K13/00

Abstract: A system for use in a poultry house includes a control server, a network gateway disposed in the poultry house and equipping with a wireless communication capability; a movable sensor module disposed in the poultry house, wherein the movable sensor module is movable within the poultry house for obtaining a plurality of environmental parameters associated with specific locations within the poultry house, and a sampling machine disposed in the poultry house for obtaining a sample of poultry waste on the ground of the poultry house. The movable sensor module transmits the environmental parameters to the network gateway, and the network gateway transmits the environmental parameters to the control server for processing the environmental parameters.

公开(公告)号：US20190000904A1

公开(公告)日：2019-01-03

申请号：US16068125

申请日：2017-01-11

Applicant: Academia Sinica

Inventor： Wen-Chin YANG ,  Lee-Tian CHANG ,  Yu-Chuan LIANG

IPC: A61K36/28 ,  A61K31/7028 ,  A61P3/04 ,  A23L33/105 ,  A23K20/105

Abstract: A composition comprising a therapeutically effective amount of Bidens pilosa extract, or an active compound isolated from the Bidens pilosa extract for use in treating obesity, reducing body weight or body weight gain, and/or gaining muscle mass or muscle content in a subject in need thereof is disclosed. The composition is useful for reducing fat cell size and/or fat accumulation in the fat cell in a subject in need thereof. The composition may further comprises an animal feed. A polyacetylenic compound for use in treating obesity, gaining muscle mass or muscle content, and/or increasing lean tissue protein content in a subject in need thereof is also disclosed. In one embodiment, the polyacetylenic compound is cytopiloyne.

公开(公告)号：US20180333447A1

公开(公告)日：2018-11-22

申请号：US15777654

申请日：2016-11-21

Applicant: Academia Sinica

Inventor： Wen-Chin YANG ,  Lee-Tian CHANG

IPC: A61K36/28 ,  A61K31/7028 ,  A61K9/14 ,  A61P1/00 ,  A23K10/30 ,  A23K50/75

CPC classification number: A61K36/28 ,  A23K10/30 ,  A23K20/163 ,  A23K50/60 ,  A23K50/70 ,  A23K50/75 ,  A23K50/80 ,  A23V2002/00 ,  A61K9/14 ,  A61K31/7028 ,  A61K31/7048 ,  A61P1/00 ,  A23V2200/3202 ,  A23V2250/28

Abstract: Beneficial effects of Bidens pilosa on gut microflora and animal health. A composition comprising a therapeutically effective amount of Bidens pilosa extract or an active compound isolated from the Bidens pilosa extract for use in promoting beneficial gut microbiota and/or inhibiting pathogenic gut microbiota in an animal in need thereof is disclosed. In one embodiment, the composition is for use in promoting growth performance or increasing body weight in an animal in need thereof. In another embodiment, the composition is for use in an animal that is not afflicted with coccidiosis.

公开(公告)号：US20170049794A1

公开(公告)日：2017-02-23

申请号：US15302938

申请日：2015-04-09

Applicant: ACADEMIA SINICA

Inventor： Wen-Chin YANG ,  Lee-Tian CHANG

IPC: A61K31/7028 ,  G01N33/68 ,  A61K45/06 ,  C12N15/113 ,  A61K31/155 ,  A61K31/4439

CPC classification number: A61K31/7028 ,  A61K31/155 ,  A61K31/216 ,  A61K31/235 ,  A61K31/341 ,  A61K31/4439 ,  A61K31/58 ,  A61K31/7105 ,  A61K38/43 ,  A61K45/06 ,  C12N15/113 ,  C12N2310/14 ,  C12N2320/30 ,  G01N33/6893 ,  G01N2333/99 ,  G01N2500/04 ,  G01N2800/042

Abstract: A Pdia4 inhibitor for use in preventing, alleviating and/or treating diabetes and/or diabetes-related complications in a subject in need thereof is disclosed, wherein the Pdia4 inhibitor does not comprise cytopiloyene. A Pdia4 inhibitor and one other anti-diabetic agent for use in combination therapy in preventing, alleviating, treating diabetes and diabetes-related complications, and/or reversing diabetes in a subject in need thereof is also disclosed, wherein the Pdia4 inhibitors for use in combination therapy may comprise cytopiloyene. Also disclosed are methods for diagnosing, treating and monitoring diabetes, and methods of screening for a Pdia4 inhibitor and/or an anti-diabetic agent.

Abstract translation: 公开了用于预防，减轻和/或治疗有需要的受试者的糖尿病和/或糖尿病相关并发症的Pdia4抑制剂，其中Pdia4抑制剂不包含细胞滴定板。 还公开了用于预防，缓解，治疗糖尿病和糖尿病相关并发症和/或逆转有需要的受试者的糖尿病的联合治疗中的Pdia4抑制剂和一种其它抗糖尿病药物，其中所述Pdia4抑制剂用于 联合治疗可能包括细胞色素 还公开了用于诊断，治疗和监测糖尿病的方法，以及筛选Pdia4抑制剂和/或抗糖尿病药的方法。

公开(公告)号：US20150272975A1

公开(公告)日：2015-10-01

申请号：US14728069

申请日：2015-06-02

Applicant: ACADEMIA SINICA

Inventor： Wen-Chin YANG ,  Lee-Tian CHANG

IPC: A61K31/7028 ,  A23K1/16 ,  A23K1/18 ,  A61K36/28

CPC classification number: A61K31/7028 ,  A23K10/30 ,  A23K20/00 ,  A23K20/10 ,  A23K20/163 ,  A23K20/195 ,  A23K50/70 ,  A23K50/75 ,  A23K50/80 ,  A23V2002/00 ,  A23V2200/32 ,  A61K36/00 ,  A61K36/28

Abstract: A composition for use in prevention, inhibition and/or treatment of coccidiosis in an animal is disclosed. The composition comprises an effective amount of Bidens pilosa, an active constituent thereof, or an active compound isolated therefrom.

Abstract translation: 公开了用于预防，抑制和/或治疗动物的球虫病的组合物。 该组合物包含有效量的Bidens pilosa，其活性组分或与其分离的活性化合物。