公开(公告)号：US20220087901A1

公开(公告)日：2022-03-24

申请号：US17425412

申请日：2020-02-12

Applicant: AMGEN INC.

Inventor： Nicholas J. Clark ,  Chia-Jung Wu ,  Mingda Eu ,  Artemio A. Alanis ,  Jennifer Lyn Sawicky ,  Monica Goss ,  Jennifer Stevenson ,  Heather N. Franey ,  Deirdre Piedmonte ,  Stephen Robert Brych

IPC: A61J1/20 ,  A61M39/00

Abstract: An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution (“IVSS”). The drug product is transferred to the prefilled delivery container via a delivery container adapter.

公开(公告)号：US20240208680A1

公开(公告)日：2024-06-27

申请号：US18288549

申请日：2022-05-19

Applicant: AMGEN INC.

Inventor： Devrishi Goswami ,  Jun Zhang ,  Deirdre Piedmonte ,  Vikashni Padmakumar ,  David Le ,  Maria Raquel Santos ,  Wei Qi

IPC: B65B3/00 ,  B65B3/12 ,  B65B3/28

CPC classification number: B65B3/003 ,  B65B3/12 ,  B65B3/28

Abstract: A method of filing a vial. The method includes providing a pump corresponding to a vial and setting a drip retraction parameter for the pump to any value equal to or less than 20 degrees. The method also includes setting a no adjustment limit for a fill weight of the vial to T1, with T1 being at or in a range of about 2% more or less than a fill weight of a target fill weight T0, wherein a process performance index Cpk (Cpk) for the vial throughout a fil cycle exceeds a minimum value.