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公开(公告)号:US20240100247A1
公开(公告)日:2024-03-28
申请号:US17767466
申请日:2020-10-01
Applicant: AMGEN INC.
Inventor: Tohid Pirbodaghi , Joshua Tamsky , Paul Daniel Faucher , Jeff Lind , Scott R. Gibson , Sheldon B. Moberg , Samin Akbari
CPC classification number: A61M5/14248 , A61M5/1454 , A61M5/16881 , A61M39/26 , A61M2005/14252
Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, and a fluid flow path. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container and a valve assembly. The fluid flow connection is coupled with the container and the needle insertion mechanism and is adapted to allow the medicament to flow from the container to the needle insertion mechanism. The valve assembly is repeatedly movable between at least a valve open position and a valve closed position to selectively allow and restrict the medicament to flow through the needle and/or the cannula.
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公开(公告)号:US20220355025A1
公开(公告)日:2022-11-10
申请号:US17641458
申请日:2020-10-05
Applicant: AMGEN INC.
Inventor: Tohid Pirbodaghi , Samin Akbari , Joshua Tamsky , Paul Daniel Faucher , Scott Robert Gibson , Sheldon B. Moberg
Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, and a needle insertion mechanism (NIM). The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism (NIM) is operably coupled with the activation mechanism and includes an actuation assembly adapted to insert a needle and a cannula to deliver the medicament from the container. The actuation assembly is movable between a storage state, a first operational state, a second operational state, and a third operational state to selectively position the needle and the cannula.
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公开(公告)号:US20220362462A1
公开(公告)日:2022-11-17
申请号:US17637507
申请日:2020-09-09
Applicant: AMGEN INC.
Inventor: Tohid Pirbodaghi , Paul Daniel Faucher , Joshua Tamsky , Scott Robert Gibson , Sheldon B. Moberg , Jeff Lind
Abstract: A drug delivery device includes a housing, a container disposed in the housing, an activation mechanism, a needle insertion mechanism, a fluid flow connection, and a valve in fluid communication with the fluid flow connection and the needle insertion mechanism. The container has an inner volume to contain a medicament which is urged out of the container by the activation mechanism. The needle insertion mechanism is adapted to insert a needle and/or a cannula to deliver the medicament from the container via the fluid flow connection. The valve is in fluid communication with the fluid flow connection and needle insertion mechanism, and is movable between first and second positions. Upon insertion of the needle and/or the cannula, the valve remains in the first position whereby fluid flow is restricted. At a later time, the valve is urged to the second position whereby fluid may flow through the needle or cannula.
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公开(公告)号:US20210316075A1
公开(公告)日:2021-10-14
申请号:US17196744
申请日:2021-03-09
Applicant: AMGEN INC
Inventor: Samin Akbari , Tohid Pirbodaghi , Sheldon B. Moberg
Abstract: Drug delivery devices and associated heating and/or cooling devices are disclosed. In an example, a drug delivery device includes a housing, a container, a therapy layer, and a first adhesive layer. The housing includes a top wall and a bottom wall. The container is at least partially disposed within the housing. The container has an inner volume to contain a drug. The therapy layer have a first side and a second side. The first side faces the bottom wall and the second side faces away from the bottom wall. The first adhesive layer couples the first side of the therapy layer and the bottom wall. The therapy layer is adapted to at least one of heat or cool an area adjacent an injection site.
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公开(公告)号:US12194280B2
公开(公告)日:2025-01-14
申请号:US17196744
申请日:2021-03-09
Applicant: AMGEN INC.
Inventor: Samin Akbari , Tohid Pirbodaghi , Sheldon B. Moberg
Abstract: Drug delivery devices and associated heating and/or cooling devices are disclosed. In an example, a drug delivery device includes a housing, a container, a therapy layer, and a first adhesive layer. The housing includes a top wall and a bottom wall. The container is at least partially disposed within the housing. The container has an inner volume to contain a drug. The therapy layer have a first side and a second side. The first side faces the bottom wall and the second side faces away from the bottom wall. The first adhesive layer couples the first side of the therapy layer and the bottom wall. The therapy layer is adapted to at least one of heat or cool an area adjacent an injection site.
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公开(公告)号:US11890450B2
公开(公告)日:2024-02-06
申请号:US16297408
申请日:2019-03-08
Applicant: AMGEN INC.
Inventor: Lawrence Scott Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher , Jeff Lind
CPC classification number: A61M5/16813 , A61M5/1413 , A61M5/14248 , A61M5/158 , A61M5/16822 , A61M39/24 , A61M5/14526 , A61M5/155 , A61M2005/1403 , A61M2005/1406 , A61M2005/14252 , A61M2039/244 , A61M2039/2406 , A61M2039/248 , A61M2039/2426 , A61M2205/3561 , A61M2205/505 , A61M2205/7527 , A61M2205/7536 , A61M2209/045
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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公开(公告)号:US20190275241A1
公开(公告)日:2019-09-12
申请号:US16297408
申请日:2019-03-08
Applicant: AMGEN INC.
Inventor: Lawrence S. Ring , Tohid Pirbodaghi , Samin Akbari , Daniel Eduardo Groszmann , Mehran Mojarrad , Mark Gordon , Mikhail Tikh , Jimmie L. Ward , Scott R. Gibson , Sheldon B. Moberg , Joshua Tamsky , Paul Faucher
Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.
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