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公开(公告)号：US10123894B2
公开(公告)日：2018-11-13
申请号：US15699938
申请日：2017-09-08
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
IPC: A61F2/958 , B21D39/04 , A61F2/91 , A61L27/00 , A61L31/06 , A61F2/86 , A61F2/844 , B29C35/08 , A61L31/14 , A61F2/89 , A61F2/82 , A61F2/915 , A61F2/95 , B29K67/00 , B29L23/00 , B29L31/00
Abstract: A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures.
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公开(公告)号：US09907685B2
公开(公告)日：2018-03-06
申请号：US14050283
申请日：2013-10-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Syed Hossainy
IPC: A61F2/82 , A61F2/958 , A61F2/91 , A61L27/00 , A61L31/06 , A61F2/86 , A61F2/844 , B29C35/08 , A61L31/14 , A61F2/89 , A61F2/915 , A61F2/95 , B29K67/00 , B29L23/00 , B29L31/00
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.
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公开(公告)号：US09827119B2
公开(公告)日：2017-11-28
申请号：US14323992
申请日：2014-07-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Boris Anukhin , Michael H. Ngo , Mikael Trollsas , Syed Hossainy , John Papp
CPC classification number: A61F2/89 , A61F2/82 , A61F2/915 , A61F2002/91508 , A61F2002/91575 , A61F2240/002 , A61M25/1034 , B23P11/005 , B29C55/24 , B29C69/00 , Y10T29/49908
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold also has a reduced crimped profile and a modification of the scaffold's ring structure at the crowns that contributes to the reduced crimped profile.
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公开(公告)号：US09345668B2
公开(公告)日：2016-05-24
申请号：US14542983
申请日：2014-11-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael H. Ngo , David J. Sherman , Syed F. A. Hossainy
IPC: A61F2/00 , A61K31/56 , A61K31/33 , A61K31/497 , A61L31/16 , A61L27/34 , A61K9/50 , A61K38/13 , A61K38/44 , A61K45/06 , A61L31/10 , A61K47/34 , A61K31/436
CPC classification number: A61L31/10 , A61K9/5031 , A61K9/5089 , A61K31/33 , A61K31/436 , A61K31/497 , A61K31/56 , A61K38/13 , A61K38/446 , A61K45/06 , A61K47/34 , A61L27/34 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2420/02 , C08L71/02 , C08L67/04
Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
Abstract translation: 本发明提供具有包含缓慢溶解性聚合物或材料的涂层的可植入装置及其制造和使用方法。
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公开(公告)号：US20150151030A1
公开(公告)日：2015-06-04
申请号：US14605666
申请日：2015-01-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , John Stankus , Nam D. Pham , Michael H. Ngo , Bozena Zofia Maslanka , Syed Faiyaz Ahmed Hossainy , Mikael Trollsas , Yiwen Tang
IPC: A61L31/16 , A61L31/14 , A61L31/10 , A61K31/436 , A61K47/34
CPC classification number: A61L31/16 , A61K31/436 , A61K47/34 , A61L31/10 , A61L31/148 , A61L2300/416 , C08L67/04
Abstract: The present invention relates to implantable medical devices coated with polymer having tunable hydrophobicity and their use in the treatment of vascular diseases.
Abstract translation: 本发明涉及涂覆有具有可调谐疏水性的聚合物的可植入医疗装置及其在治疗血管疾病中的用途。
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Patent Agency Ranking
公开(公告)号：US20150142099A1
公开(公告)日：2015-05-21
申请号：US14603087
申请日：2015-01-22
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John S. Stankus , Hugh Zhao , Mikael Trollsas , Syed Faiyaz Ahmed Hossainy , Michael H. Ngo , Yunbing Wang , Benny Serna
IPC: A61F2/86
CPC classification number: A61F2/86 , A61F2/915 , A61F2002/91508 , A61F2002/91541 , A61F2002/91558 , A61F2210/0019 , A61F2230/0054 , A61F2230/0056 , A61F2230/006 , A61F2250/001 , A61L31/041 , A61L31/06 , A61L31/14 , A61L31/148 , A61L31/16 , A61L2400/16 , C08L67/04
Abstract: Bioabsorbable scaffolds having high crush recoverability, high fracture resistance, and reduced or no recoil due to self expanding properties at physiological conditions are disclosed. The scaffolds are made from a random copolymer of PLLA and a rubbery polymer such as polycaprolactone.
Abstract translation: 公开了具有高压碎可恢复性，高抗断裂性和由于在生理条件下的自膨胀性能而减少或无反冲的生物可吸收支架。 支架由PLLA和橡胶状聚合物如聚己内酯的无规共聚物制成。
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公开(公告)号：US20160030217A1
公开(公告)日：2016-02-04
申请号：US14881073
申请日：2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.
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公开(公告)号：US09066992B2
公开(公告)日：2015-06-30
申请号：US13903773
申请日：2013-05-28
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John J. Stankus , O. Mikael Trollsas , Michael H. Ngo
CPC classification number: A61L27/18 , A61L27/34 , A61L27/54 , A61L2400/16 , C08G2230/00 , C08G2280/00 , C08L75/04
Abstract: The present invention is directed to polymeric compositions comprising a biodegradable copolymer that possesses shape-memory properties and implantable devices (e.g., drug-delivery stents) formed of materials (e.g., a coating) containing such compositions. The polymeric compositions can also contain at least one non-fouling moiety, at least additional biocompatible polymer, at least one biobeneficial material, at least one bioactive agent, or a combination thereof. The polymeric compositions are formulated to possess good mechanical, physical and biological properties. Moreover, implantable devices formed of materials comprising such compositions can be delivered to the treatment site in a conveniently compressed size and then can expand to dimensions appropriate for their medical functions.
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9.发明申请Block Copolymer Comprising at least one Polyester Block and at least one Poly(ethylene glycol) Block 审中-公开嵌段共聚物包含至少一个聚酯嵌段和至少一个聚（乙二醇）嵌段公开(公告)号：US20150174300A1
公开(公告)日：2015-06-25
申请号：US14580101
申请日：2014-12-22
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： O. Mikael Trollsas , Michael H. Ngo , Syed F. A. Hossainy , David J. Sherman
CPC classification number: A61L31/10 , A61L31/047 , A61L31/06 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C08L71/02 , C08L67/04
Abstract: The present invention provides a block copolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.
Abstract translation: 本发明提供了用于控制药物释放的可植入装置上的涂层的嵌段共聚物及其制备和使用方法。
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公开(公告)号：US20140364935A1
公开(公告)日：2014-12-11
申请号：US13910998
申请日：2013-06-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Erik David Eli , Syed Hossainy , Mikael Trollsas , Michael H. Ngo , Stephen Pacetti , Michael Green , John Papp
IPC: A61F2/07
CPC classification number: A61F2/915 , A61F2/91 , A61F2/958 , A61F2002/828 , A61F2002/91575 , A61F2002/91591 , A61F2210/0004 , A61F2220/0075 , A61F2220/0091
Abstract: A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.
Abstract translation: 支架由仅通过至少一个联接件彼此连接或连接的若干段形成。 联轴器在轴向方向上在轴向位移的有限距离上使分段解耦。 当支架植入外周血管时，由于在有限的距离上沿着轴向方向的分段，分段的环上的载荷减小。
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