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公开(公告)号：US09902722B2
公开(公告)日：2018-02-27
申请号：US15300618
申请日：2015-04-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Guanglin Luo , Ling Chen , Carolyn Diane Dzierba , Jonathan L. Ditta , John E. Macor , Joanne J. Bronson
IPC: C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D237/08 , C07D239/26 , C07D213/34 , A61K31/50 , A61K31/51 , A61K31/505 , A61K31/506 , A61K31/44 , C07D471/04 , C07D213/75 , C07D213/73 , C07D413/10 , C07D213/57 , C07D213/64 , C07D213/30 , C07D213/61 , C07D215/14 , C07D213/80 , C07D309/22 , C07C233/25 , A61K31/4427 , A61P25/28
CPC classification number: C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
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公开(公告)号：US08901305B2
公开(公告)日：2014-12-02
申请号：US13946344
申请日：2013-07-19
Applicant: Bristol-Myers Squibb Company
Inventor： Vivekananda M. Vrudhula , Senliang Pan , Ramkumar Rajamani , Susheel Jethanand Nara , Maheswaran Sivasamban Karatholuvhu , Tarun Kumar Maishal , Jonathan L. Ditta , Carolyn Diane Dzierba , Joanne J. Bronson , John E. Macor
IPC: A61K31/44 , C07D471/00 , C07D471/04
CPC classification number: C07D471/04
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
Abstract translation: 本公开一般涉及可抑制AAK1（衔接子相关激酶1），包含这些化合物的组合物和抑制AAK1的方法的化合物。
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公开(公告)号：US10246469B2
公开(公告)日：2019-04-02
申请号：US15763281
申请日：2016-09-29
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Joanne J. Bronson , Ling Chen , Jonathan L. Ditta , Carolyn Diane Dzierba , Prasada Rao Jalagam , Guanglin Luo , John E. Macor , Tarun Kumar Maishal , Susheel Jethanand Nara , Ramkumar Rajamani , Ramesh Kumar Sistla , Soodamani Thangavel
IPC: C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , C07D237/08 , C07D239/26 , C07D213/34 , A61K31/50 , A61K31/51 , A61K31/505 , A61K31/506 , A61K31/44 , A61K31/4427 , A61P25/28 , C07D513/04 , A61P25/18 , A61P25/16 , C07D213/74
Abstract: The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.
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公开(公告)号：US20140038999A1
公开(公告)日：2014-02-06
申请号：US13946344
申请日：2013-07-19
Applicant: Bristol-Myers Squibb Company
Inventor： Vivekananda M. Vrudhula , Senliang Pan , Ramkumar Rajamani , Susheel Jethanand Nara , Maheswaran Sivasamban Karatholuvhu , Tarun Kumar Maishal , Jonathan L. Ditta , Carolyn Diane Dzierba , Joanne J. Bronson , John E. Macor
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
Abstract translation: 本公开一般涉及可以抑制AAK1（衔接子相关激酶1），包含这些化合物的组合物和抑制AAK1的方法的化合物。
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Patent Agency Ranking
公开(公告)号：US20180346440A1
公开(公告)日：2018-12-06
申请号：US15763280
申请日：2016-09-29
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Joanne J. Bronson , Ling Chen , Jonathan L. Ditta , Carolyn Diane Dzierba , Prasada Rao Jalagam , Guanglin Luo , John E. Macor , Tarun Kumar Maishal , Susheel Jethanand Nara , Ramkumar Rajamani , Ramesh Kumar Sistla , Soodamani Thangavel
IPC: C07D401/04 , C07D413/14 , A61P25/16 , A61P25/28 , A61P25/18 , A61P25/02
Abstract: The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.
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公开(公告)号：US20180134704A1
公开(公告)日：2018-05-17
申请号：US15865848
申请日：2018-01-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Guanglin Luo , Ling Chen , Carolyn Diane Dzierba , Jonathan L. Ditta , John E. Macor , Joanne J. Bronson
IPC: C07D471/04 , C07D413/10 , A61K31/50 , C07D401/04 , C07D309/22 , C07D239/26 , C07D237/08 , C07D215/14 , C07D213/80 , C07D213/75 , C07D213/73 , C07D213/64 , C07D213/61 , C07D213/57 , C07D213/34 , C07D213/30 , C07C233/25 , C07D401/14
CPC classification number: C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
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公开(公告)号：US20170183340A1
公开(公告)日：2017-06-29
申请号：US15300618
申请日：2015-04-01
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Guanglin Luo , Ling Chen , Carolyn Diane Dzierba , Jonathan L. Ditta , John E. Macor , Joanne J. Bronson
IPC: C07D471/04 , C07D213/73 , C07D413/10 , C07D213/57 , C07D213/64 , C07D213/30 , C07D213/61 , C07D215/14 , C07D401/04 , C07D401/14 , C07D237/08 , C07D213/80 , C07D213/34 , C07D239/26 , C07D309/22 , C07C233/25 , C07D213/75
CPC classification number: C07D471/04 , A61K31/4427 , A61K31/50 , A61P25/28 , C07C233/25 , C07D213/30 , C07D213/34 , C07D213/57 , C07D213/61 , C07D213/64 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/80 , C07D215/14 , C07D237/08 , C07D239/26 , C07D309/18 , C07D309/22 , C07D401/04 , C07D401/14 , C07D413/10
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
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公开(公告)号：US10544120B2
公开(公告)日：2020-01-28
申请号：US15763280
申请日：2016-09-29
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Joanne J. Bronson , Ling Chen , Jonathan L. Ditta , Carolyn Diane Dzierba , Prasada Rao Jalagam , Guanglin Luo , John E. Macor , Tarun Kumar Maishal , Susheel Jethanand Nara , Ramkumar Rajamani , Ramesh Kumar Sistla , Soodamani Thangavel
IPC: C07D401/04 , C07D413/14 , A61P25/16 , A61P25/28 , A61P25/18 , A61P25/02
Abstract: The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.
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公开(公告)号：US20160333006A1
公开(公告)日：2016-11-17
申请号：US15111416
申请日：2014-01-29
Applicant: Bristol-Myers Squibb Company
Inventor： Vivekananda M. Vrudhula , Senliang Pan , Ramkumar Rajamani , Susheel Jethanand Nara , Maheswaran Sivasamban Karatholuvhu , Tarun Kumar Maishal , Jonathan L. Ditta , Carolyn Diane Dzierba , Joanne J Bronson , John E. Macor
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
Abstract translation: 本公开一般涉及可以抑制AAK1（衔接子相关激酶1），包含这些化合物的组合物和抑制AAK1的方法的化合物。
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