公开(公告)号：US20210123056A1

公开(公告)日：2021-04-29

申请号：US17052610

申请日：2019-05-03

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Anna Hickey ,  Caitlin Huddleston ,  Vinoth Sankarapani

IPC: C12N15/115

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as herbicides, such as dicamba.

公开(公告)号：US10920228B2

公开(公告)日：2021-02-16

申请号：US16262769

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu

IPC: C12N15/11 ,  C12N15/115 ,  C12N15/10

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as biocide molecules.

公开(公告)号：US20190249245A1

公开(公告)日：2019-08-15

申请号：US16262777

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Rafal Drabek ,  Caitlin Bruns

IPC: C12Q1/6874 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6876 ,  C12Q1/6848 ,  C40B30/04

CPC classification number: C12Q1/6874 ,  C12N15/1048 ,  C12N15/115 ,  C12N2310/16 ,  C12N2330/31 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as lipoarabinomannan (LAM).

公开(公告)号：US11608356B1

公开(公告)日：2023-03-21

申请号：US16798314

申请日：2020-02-22

Applicant: Base Pair Biotechnologies, Inc.

Inventor： Robert Batchelor ,  George W. Jackson ,  Truong Nguyen ,  Vinoth Sankarapani

IPC: C12N15/115 ,  C07H21/04 ,  C07H21/02

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as antibiotics, such as colistin.

公开(公告)号：US20210395920A1

公开(公告)日：2021-12-23

申请号：US17460513

申请日：2021-08-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.

公开(公告)号：US20240110237A1

公开(公告)日：2024-04-04

申请号：US18227386

申请日：2023-07-28

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： Jasmine Kaur ,  Rafal Drabek ,  George W. Jackson ,  Robert Batchelor ,  Alexander Chiu

IPC: C12Q1/6874 ,  C12N15/10 ,  C12N15/115 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04

CPC classification number: C12Q1/6874 ,  C12N15/1048 ,  C12N15/115 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04 ,  C12N2310/16 ,  C12N2330/31

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules.

公开(公告)号：US20210348226A1

公开(公告)日：2021-11-11

申请号：US17152007

申请日：2021-01-19

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： Jasmine Kaur ,  Rafal Drabek ,  George W. Jackson ,  Robert Batchelor ,  Alexander Chiu

IPC: C12Q1/6874 ,  C12N15/115 ,  C12N15/10 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6876 ,  C40B30/04

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as opioids and opioid derivatives.

公开(公告)号：US10927381B2

公开(公告)日：2021-02-23

申请号：US16677433

申请日：2019-11-07

Applicant: BASE PAIR BIOTECHNOLOGIES, INC.

Inventor： George W. Jackson ,  Robert Batchelor ,  Truong Nguyen ,  Victoria Singer ,  Garam Lee ,  Rafal Drabek

IPC: C07H21/00 ,  C12N15/115 ,  C40B30/04 ,  C40B10/00

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as molecules used proteins or peptides, such as LL37.

公开(公告)号：US20210041470A1

公开(公告)日：2021-02-11

申请号：US16832019

申请日：2020-03-27

Applicant: Base Pair Biotechnologies, Inc.

Inventor： Jasmine Kaur ,  Rafal Drabek ,  George W. Jackson ,  Robert Batchelor

IPC: G01N33/94 ,  C12N15/11 ,  G01N33/50

Abstract: The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules, such as opioids and opioid metabolites.

公开(公告)号：US11111603B2

公开(公告)日：2021-09-07

申请号：US16262825

申请日：2019-01-30

Applicant: Base Pair Biotechnologies, Inc.

Inventor： George W. Jackson ,  Robert Batchelor ,  Alexander S. Chiu ,  Rafal Drabek ,  Deepak Thirunavukarasu ,  Caitlin Bruns

IPC: C07H21/04 ,  C40B40/06 ,  C12Q1/6811 ,  C12Q1/6837

Abstract: This invention relates to methods and materials for multiplexed utilization of collections of functional ligands, particularly to methods and materials for selecting for and/or utilizing particular desirable traits of functional ligands in a multiplexed manner, and more particularly to methods and materials for selecting for and/or utilizing particular structural changes of functional ligands in a multiplexed manner.