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公开(公告)号：US12036029B2
公开(公告)日：2024-07-16
申请号：US17351357
申请日：2021-06-18
发明人： Lior Botzer , Meir Bar-Tal , Elad Nakar
CPC分类号： A61B5/367 , A61B5/316 , A61B5/339 , A61B5/352 , A61B5/6869 , A61B5/7239 , A61B5/743 , A61B5/287 , A61B5/6852 , A61B2505/05
摘要： A method, including receiving a unipolar ECG signal from the location in the heart from a selected one electrode of a pair of electrodes, computing a local unipolar minimum derivative of the unipolar signal at a plurality of times of occurrences of the local unipolar minimum derivative, identifying candidate time of occurrences of the plurality of times of occurrences of the local unipolar minimum derivative as candidate annotations of the time of activation of the myocardium, extracting features for each of the candidate annotations, assigning a confidence level based on a feature value for each of the candidate annotations, eliminating candidate annotations that have a confidence level below a threshold and generating a local activation time map using the remaining candidate annotations.
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公开(公告)号：US20220061731A1
公开(公告)日：2022-03-03
申请号：US17523244
申请日：2021-11-10
发明人： Elad Nakar , Amir Ben-Dor , Noam Seker Gafni
摘要： A method including processing electrocardiograph (ECG) signals taken over a heartbeat received over a plurality of channels, selecting a subset of the ECG signals captured at a point in time with a window of interest (WOI) around reference annotations and having a morphology pattern within the WOI, storing the morphology patterns, receiving continuous sets of ECG signals taken over a plurality of heartbeats over the plurality of channels and having a morphology pattern within the WOI, performing a correlation between the stored morphology patterns of the ECH signals and the morphology patterns of the continuous sets of ECH signals for each heartbeat, generating a correlation coefficient that is a measure of a goodness of fit between geometries of the ECG signals and the continuous sets of ECG signals and identifying each heartbeat having a correlation coefficient that exceeds a threshold coefficient as having been caused by an arrhythmia.
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公开(公告)号：US20210391082A1
公开(公告)日：2021-12-16
申请号：US17342321
申请日：2021-06-08
发明人： Yariv Avraham Amos , Matityahu Amit , Stanislav Goldberg , Lior Botzer , Jonathan Yarnitsky , Elad Nakar , Eliyahu Ravuna
摘要： A method is provided. The method is implemented by a detection engine embodied in processor executable code stored on a memory and executed by at least one processor. The method includes modeling a vector velocity field that measures and quantifies a velocity of electrocardiogram data signals that pass through a local activation time. The method further includes determining codes for each point in plane to provide a color code vector field image; detecting focal and rotor indications by using kernels to scan the color coded vector field image; and classifying the focal and rotor indications into perpetuators.
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公开(公告)号：US20210169359A1
公开(公告)日：2021-06-10
申请号：US16952943
申请日：2020-11-19
发明人： Meir Bar-Tal , Vladimir Rubinstein , Jonathan Yarnitsky , Elad Nakar , Amiram Ben-Dor , Aharon Turgeman
IPC分类号： A61B5/046 , A61B5/00 , A61B5/04 , A61B5/06 , A61B5/0488
摘要： Methods, apparatuses, and systems for intra-cardiac pattern matching are disclosed. A unipolar pattern intra-cardiac (IC) electromyography (EGM) signals is received for an area of a heart from a plurality of activity channels corresponding to a plurality of electrodes of a catheter. A window of interest (WOI) of the IC EGM signals is received representing an entire cycle length for a single heartbeat. A pattern of interest (POI) is selected to include a portion of WOI corresponding to an arrhythmia activation. A template POI is generated representative of the arrhythmia activation. Subsequent electrical activity is received, weights are applied and the subsequent electrical activity is compared with the template POI. A correlation score is generated and compared with a threshold correlation score.
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公开(公告)号：US20230284960A1
公开(公告)日：2023-09-14
申请号：US17692232
申请日：2022-03-11
发明人： Marc Wolff , Elad Nakar , Eliyahu Ravuna , Nir Yanovich , Hadar Reuveny
CPC分类号： A61B5/353 , A61B5/367 , A61B5/283 , A61B5/7235
摘要： A method includes acquiring intracardiac unipolar signals and intracardiac bipolar signals at a given region of a heart of a patient. The unipolar signals are pruned by eliminating ones of the unipolar signals that correspond in time to respective bipolar signals. One or more unipolar signals are identified among the pruned unipolar signals, that are associated with far-field P-waves. Using the identified P-waves, a window of interest (WOI) is set on electrograms acquired in an atrium of the heart, and, using the electrograms having the set WOI, an electrophysiological (EP) map is generated, of the atrium indicative of atrial tachycardia (AT) tissue locations therein.
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公开(公告)号：US20230020372A1
公开(公告)日：2023-01-19
申请号：US17379200
申请日：2021-07-19
发明人： Leonid Zaides , Elad Nakar , Eliyahu Ravuna , Yoav Benaroya , Refael Itah
摘要： A method includes receiving a plurality of data points including electrical activation (EA) values measured at respective positions in at least a portion of a surface of a cardiac chamber of a heart of a patient. Using a predefined EA value criterion, the EA values in a given region of the cardiac surface are classified into multiple distinct EA wave-fronts, and multiple layers of EA values are calculated for the given region, wherein each EA layer includes the EA values found to belong to a respective and contiguous EA wave-front. The multiple EA layers are overlayed on a graphical representation of the surface. The graphical representation with the multiple overlaid EA layers is displayed to a user, with a graphical indication distinguishing between the multiple EA layers.
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公开(公告)号：US20220387100A1
公开(公告)日：2022-12-08
申请号：US17341315
申请日：2021-06-07
IPC分类号： A61B18/14
摘要： In one embodiment, a medical system includes a catheter configured to be inserted into a chamber of a heart of a living subject, and including multiple electrodes configured to capture electrical activity from electrical activation signals propagating in tissue of the chamber, a display, and processing circuitry configured to automatically select bipolar signals to be captured into an electro-anatomical map from respective electrode pairs of the multiple electrodes responsively to an alignment of the respective electrode pairs with a direction of propagation of the electrical activation signals, and render the electro-anatomical map to the display.
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公开(公告)号：US11278233B2
公开(公告)日：2022-03-22
申请号：US16685496
申请日：2019-11-15
发明人： Eliyahu Ravuna , Yaron Kadoshi , Refael Itah , Elad Nakar , Michal Alroy Levy
摘要： Methods, apparatus, and systems for medical procedures are disclosed herein and include detecting points of an intra-cardiac area that exhibits abnormal activations, such as local abnormal ventricular activations (LAVAs). Points that exhibit such abnormal activations may be referred to as seed points that are identified during a first step of the process disclosed herein. The seed points may be identified using one or more inputs such as unipolar and bipolar mapping channels, body surface ECGs, past activations, neighboring points and the like during the first step which prioritizes high specificity over sensitivity. During a second step which prioritizes high sensitivity, electrical activations of neighboring points near the seed points are analyzed to determine if the activations are similar (e.g., have a similar time) as the abnormal activations corresponding to the corresponding seed points.
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公开(公告)号：US20210338131A1
公开(公告)日：2021-11-04
申请号：US17373289
申请日：2021-07-12
发明人： Lior Botzer , Meir Bar-Tal , Elad Nakar , Noga Salomon
摘要： A method, including receiving a bipolar signal from a pair of electrodes in proximity to a myocardium of a human subject, and receiving a unipolar signal from a selected one of the pair of electrodes. The method further includes delineating a window of interest (WOI) for the unipolar and bipolar signals, within the WOI computing local unipolar minimum derivatives of the unipolar signal, and times of occurrence of the local unipolar minimum derivatives, and within the WOI computing bipolar derivatives of the bipolar signal at the times of occurrence. The method also includes evaluating ratios of the bipolar derivatives to the local unipolar minimum derivatives, and when the ratios are greater than a preset threshold ratio value, assigning the times of occurrence as times of activation of the myocardium, counting a number of the times of activation; and classifying the unipolar signal according to the number.
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公开(公告)号：US20190336027A1
公开(公告)日：2019-11-07
申请号：US16514091
申请日：2019-07-17
发明人： Lior Botzer , Meir Bar-Tal , Elad Nakar
IPC分类号： A61B5/04 , A61B5/00 , A61B5/0456 , A61B5/042
摘要： A method, including receiving a bipolar ECG signal from a location in the heart from the pair of electrodes, receiving a unipolar ECG signal from the location in the heart from a selected one electrode of the pair of electrodes, computing a local unipolar minimum derivative of the unipolar signal at a plurality of times of occurrences of the local unipolar minimum derivative, computing a bipolar derivative of the bipolar signal, evaluating a ratio of the bipolar derivative to the local unipolar minimum derivative at the plurality of times of occurrences of the local unipolar minimum derivative, annotating each time of occurrence as a time of activation of the myocardium at the location in the heart when the ratio is greater than a preset threshold value, merging two annotations that arise from a single occurrence as a single annotation, evaluating features of the annotations and assigning a confidence level to each feature, eliminating annotations that have a confidence level below a threshold and generating a local activation time map using the remaining annotations.
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