公开(公告)号：US20150360009A1

公开(公告)日：2015-12-17

申请号：US14738208

申请日：2015-06-12

Applicant: Boston Scientific SciMed, Inc. ,  Mayo Foundation for Medical Education and Research

Inventor： Roger McGowan ,  Kim Davis ,  Rachel Japuntich ,  Umang Anand ,  Raghav Goel ,  Peter M. Pollak ,  Douglas Pennington ,  Atta Behfar ,  Charles J. Bruce ,  Paul A. Friedman ,  Bruce D. Johnson ,  Lyle D. Joyce ,  Lyle J. Olson

IPC: A61M27/00 ,  A61M39/22 ,  A61M1/36 ,  A61M25/10 ,  A61M5/00

CPC classification number: A61M39/22 ,  A61B17/12031 ,  A61B17/1204 ,  A61B17/12109 ,  A61B17/12136 ,  A61B2017/00336 ,  A61B2017/00853 ,  A61M1/3666 ,  A61M5/007 ,  A61M25/0023 ,  A61M25/0097 ,  A61M25/0133 ,  A61M31/005 ,  A61M2025/0024 ,  A61M2025/1052

Abstract: Multifunctional occlusion crossover devices include features to improve the crossover balloon occlusion technique used during transcatheter aortic valve replacement procedures, for example. The devices include a compliant balloon incorporated with a highly flexible and lubricous sheath system. The balloon is capable of safely occluding from the common iliac artery and down to an access site in the femoral artery. The devices can simplify the CBOT technique and replace multiple devices currently used for the procedure.

Abstract translation: 多功能闭塞交叉装置包括用于改善经导管主动脉瓣置换手术中使用的交叉球囊阻塞技术的特征。 这些装置包括结合有高柔性和润滑护套系统的顺应性球囊。 气球能够从髂总动脉和股动脉进入位置安全地闭塞。 这些设备可以简化CBOT技术并替换当前用于该过程的多个设备。

公开(公告)号：US20160220357A1

公开(公告)日：2016-08-04

申请号：US15015298

申请日：2016-02-04

Applicant: Boston Scientific Scimed, Inc. ,  Mayo Foundation for Medical Education and Research

Inventor： Umang Anand ,  Raghav Goel ,  Roger W. McGowan ,  Daniel Ross ,  Patrick A. Haverkost ,  Mary M. Byron ,  David R. Wulfman ,  James P. Rohl ,  Peter M. Pollak ,  Lyle J. Olson ,  Atta Behfar ,  Charles J. Bruce

IPC: A61F2/24

CPC classification number: A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00606 ,  A61B2017/00623 ,  A61F2/24 ,  A61F2210/0014 ,  A61F2230/0069

Abstract: Devices provided herein can include implantable transseptal flow control components adapted to be implanted in an opening in a septal wall. In a closed configuration, the implantable transseptal flow control components provided herein prevent blood from flowing through the opening. In an open configuration, the implantable transseptal flow control components provided herein allow blood to flow from the left atrium to the right atrium. In a closed configuration, implantable transseptal flow control components provided herein can be configured such that blood does not stagnate at a location proximate to a left atrium flow control component side when the pressure differential is below a second predetermined threshold pressure value.Implantable transseptal flow control components provided herein can remain in a closed configuration when a pressure differential between the left atrium and the right atrium is less than a first non-zero predetermined threshold pressure value.

Abstract translation: 本文提供的装置可包括适于植入隔壁中的开口的可植入经血流控制部件。 在闭合构造中，本文提供的可植入经血流控制组件防止血液流过开口。 在开放构型中，本文提供的可植入经血流控制组件允许血液从左心房流向右心房。 在闭合构造中，本文提供的可植入经血流控制部件可被构造成使得当压力差低于第二预定阈值压力值时，血液不会滞留在靠近左心房流量控制部件侧的位置处。 当左心房和右心房之间的压力差小于第一非零预定阈值压力值时，本文提供的可植入经血流量控制组件可以保持在闭合配置。

公开(公告)号：US20150018431A1

公开(公告)日：2015-01-15

申请号：US14330734

申请日：2014-07-14

Applicant: Boston Scientific Scimed, Inc.

Inventor： Hongxia Zeng ,  Jan Seppala ,  Yen-Lane Chen ,  Raghav Goel

IPC: C10M107/42

CPC classification number: C10M107/42 ,  A61L27/34 ,  A61L27/50 ,  A61L29/085 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14 ,  A61L2400/10 ,  C08L39/06

Abstract: In one aspect, the present disclosure pertains to lubricous coating compositions that comprise (a) a higher molecular weight polyvinylpyrrolidone, (b) a lower molecular weight polyvinylpyrrolidone, and (c) a polyfunctional unsaturated crosslinking agent. In some embodiments, such lubricous coating compositions are present in crosslinked form on the surface of a medical article. In some embodiments, the lubricous coating compositions further comprise a solvent, in which case such compositions may be, for example, applied to a substrate in the form of a layer and subsequently crosslinked, thereby forming a lubricious coating on the substrate. In another aspect, the present disclosure is directed to methods for forming various medical articles.

Abstract translation: 一方面，本公开内容涉及包含（a）较高分子量聚乙烯吡咯烷酮，（b）较低分子量聚乙烯吡咯烷酮和（c）多官能不饱和交联剂的润滑涂料组合物。 在一些实施方案中，这种润滑涂料组合物以交联形式存在于医疗制品的表面上。 在一些实施方案中，润滑涂料组合物还包含溶剂，在这种情况下，这种组合物可以例如以层的形式施用于基底并随后交联，从而在基底上形成润滑涂层。 在另一方面，本公开涉及用于形成各种医疗制品的方法。