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公开(公告)号：US11059836B2
公开(公告)日：2021-07-13
申请号：US16530594
申请日：2019-08-02
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Samuel Coe , Peter David Johnson , Michael Edward Prime , Christopher John Brown , Sébastien René Gabriel Galan , Paul Richard Giles , Jonathan Bard , Elise Luciennen Paulette Gadouleau , Thomas Martin Krülle , Daniel Clark-Frew , John Wityak , Alex Kiselyov , Sarah Hayes
IPC: C07D513/04 , C07D413/14 , C07D417/04 , A61K51/04 , C07D413/12 , C07D263/57 , C07D498/04 , C07D405/14 , C07D413/04 , C07D471/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20210060187A1
公开(公告)日：2021-03-04
申请号：US16987277
申请日：2020-08-06
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20170056535A1
公开(公告)日：2017-03-02
申请号：US15249223
申请日：2016-08-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Louise Jones Green , Sarah Hayes
IPC: A61K51/04 , C07D487/04 , C07D513/14 , C07D513/04
CPC classification number: A61K51/0455 , A61K51/0459 , C07B59/002 , C07D487/04 , C07D513/04 , C07D513/14
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
Abstract translation: 提供了包含式I化合物或其药学上可接受的盐的成像剂及其使用方法。 （一世）。
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公开(公告)号：US12258355B2
公开(公告)日：2025-03-25
申请号：US17881895
申请日：2022-08-05
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Samuel Coe , Peter David Johnson , Michael Edward Prime , Christopher John Brown , Sébastien René Gabriel Galan , Paul Richard Giles , Jonathan Bard , Elise Lucienne Paulette Gadouleau , Thomas Martin Krülle , Daniel Clark-Frew , John Wityak , Alex Kiselyov , Sarah Hayes
IPC: C07D513/04 , A61B5/00 , A61B6/03 , A61K51/04 , C07D263/57 , C07D405/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D471/04 , C07D498/04
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20220409600A1
公开(公告)日：2022-12-29
申请号：US17752683
申请日：2022-05-24
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Jonathan Bard , Matthew R. Lee , Longbin Liu , Michael Edward Prime , Samuel Coe
IPC: A61K31/454 , A61K47/54 , A61K31/165 , A61K31/427
Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
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Patent Agency Ranking
公开(公告)号：US10479802B2
公开(公告)日：2019-11-19
申请号：US15507208
申请日：2015-08-28
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Samuel Coe , Jonathan Bard , Peter David Johnson , Michael Edward Prime , Christopher John Brown , Sébastien René Gabriel Galan , Paul Richard Giles , Elise Luciennen Paulette Gadouleau , Thomas Martin Krülle , Daniel Clark-Frew , John Wityak , Alex Kiselyov , Sarah Hayes
IPC: C07D513/04 , C07D413/14 , C07D471/04 , A61K51/04 , C07D413/12 , C07D263/57 , C07D498/04 , C07D405/14 , C07D413/04
Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10765764B2
公开(公告)日：2020-09-08
申请号：US16172425
申请日：2018-10-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20200276176A1
公开(公告)日：2020-09-03
申请号：US16799651
申请日：2020-02-24
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Jonathan Bard , Matthew R. Lee , Longbin Liu , Michael Edward Prime , Samuel Coe
IPC: A61K31/454 , A61K31/427 , A61K31/165 , A61K47/54
Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
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公开(公告)号：US20190167821A1
公开(公告)日：2019-06-06
申请号：US16172425
申请日：2018-10-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07B59/00 , C07D513/04 , C07D487/04 , C07D513/14
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10137211B2
公开(公告)日：2018-11-27
申请号：US15249223
申请日：2016-08-26
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC: A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use
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