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公开(公告)号：US20210236663A1
公开(公告)日：2021-08-05
申请号：US17125905
申请日：2020-12-17
发明人： Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Christopher John Brown , Sarah Hayes , Adrian Kotey , Matthew Robert Mills , Michael Edward Prime
IPC分类号： A61K51/04 , C07D401/14 , C07D401/06 , C07D471/04 , C07D401/12 , C07D491/107 , C07D487/04 , C07D413/14 , C07B59/00
摘要： Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号：US20210060187A1
公开(公告)日：2021-03-04
申请号：US16987277
申请日：2020-08-06
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC分类号： A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US11344637B2
公开(公告)日：2022-05-31
申请号：US16987277
申请日：2020-08-06
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC分类号： A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10765764B2
公开(公告)日：2020-09-08
申请号：US16172425
申请日：2018-10-26
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC分类号： A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US20190167821A1
公开(公告)日：2019-06-06
申请号：US16172425
申请日：2018-10-26
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC分类号： A61K51/04 , C07B59/00 , C07D513/04 , C07D487/04 , C07D513/14
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
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公开(公告)号：US10137211B2
公开(公告)日：2018-11-27
申请号：US15249223
申请日：2016-08-26
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Brown , Sarah Hayes
IPC分类号： A61K51/04 , C07D513/04 , C07D487/04 , C07D513/14 , C07B59/00
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use
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公开(公告)号：US11992535B2
公开(公告)日：2024-05-28
申请号：US17125905
申请日：2020-12-17
发明人： Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Christopher John Brown , Sarah Hayes , Adrian Kotey , Matthew Robert Mills , Michael Edward Prime
IPC分类号： A61K51/04 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107
CPC分类号： A61K51/0455 , A61K51/0459 , A61K51/0468 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107 , C07B2200/05
摘要： Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号：US20170056535A1
公开(公告)日：2017-03-02
申请号：US15249223
申请日：2016-08-26
发明人： Celia Dominguez , John Wityak , Jonathan Bard , Christopher John Brown , Michael Edward Prime , Peter David Johnson , Thomas Martin Krulle , Daniel Clark-Frew , Duane Higgins , Matthew Robert Mills , Richard Waldron Marston , Samuel Coe , Samantha Louise Jones Green , Sarah Hayes
IPC分类号： A61K51/04 , C07D487/04 , C07D513/14 , C07D513/04
CPC分类号： A61K51/0455 , A61K51/0459 , C07B59/002 , C07D487/04 , C07D513/04 , C07D513/14
摘要： Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
摘要翻译： 提供了包含式I化合物或其药学上可接受的盐的成像剂及其使用方法。 （一世）。
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公开(公告)号：US20240342317A1
公开(公告)日：2024-10-17
申请号：US18402399
申请日：2024-01-02
发明人： Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC分类号： A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC分类号： A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
摘要： Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号：US11918662B2
公开(公告)日：2024-03-05
申请号：US17344582
申请日：2021-06-10
发明人： Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC分类号： A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC分类号： A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
摘要： Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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