公开(公告)号：US20230088135A1

公开(公告)日：2023-03-23

申请号：US17760462

申请日：2021-05-13

Applicant: CJ CheilJedang Corporation

Inventor： Hayun LEE ,  Ju Eun KIM ,  Jihyun SHIM ,  Ji Hye LEE ,  Sung Gun LEE

IPC: C12P13/06 ,  C12N9/10 ,  C12N15/77

Abstract: The present application relates to: a novel mutant polypeptide having isopropylmalate synthase activity; and a method for producing L-leucine by using same. L-leucine can be produced at high yield by using the mutant polypeptide according to an embodiment.

公开(公告)号：US20200208182A1

公开(公告)日：2020-07-02

申请号：US16622490

申请日：2018-06-14

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Seon Hye KIM ,  Su Jin PARK ,  Kyoung Min LEE ,  Kyungsu NA ,  Hong Xian LI ,  Hyun-jung BAE ,  Jihyun SHIM ,  Young Lyeol YANG ,  Hye Won UM ,  Hyo Hyoung LEE ,  Min Gyeong KANG ,  Hye Won KIM ,  Byeong Cheol SONG ,  Haena OH ,  Han Hyoung LEE

IPC: C12P13/10 ,  C12P13/00

Abstract: The present disclosure relates to a novel polypeptide having an ability to export an ornithine-based product, and a method for producing an ornithine-based product using the same.

公开(公告)号：US20240167065A1

公开(公告)日：2024-05-23

申请号：US17766389

申请日：2021-07-01

Applicant: CJ CheilJedang Corporation

Inventor： Kwang Soo SHIN ,  Kwang Woo LEE ,  Yee-Seul SO ,  Yeon-Jae JANG ,  Jihyun SHIM

IPC: C12P13/02 ,  C12N9/10 ,  C12N15/77 ,  C12P7/42 ,  C12R1/15

CPC classification number: C12P13/02 ,  C12N9/1014 ,  C12N15/77 ,  C12P7/42 ,  C12R2001/15 ,  C12Y201/02011

Abstract: Provided are: a polypeptide having activity of 3-methyl-2-oxobutanoate hydroxymethyltransferase; a microorganism having increased activity of 3-methyl-2-oxobutanoate hydroxymethyltransferase; a composition for producing pantothenic acid and/or pantoic acid, comprising the polypeptide and/or the microorganism, and a pantothenic acid and/or pantoic acid production method comprising a step for culturing the microorganism.

公开(公告)号：US20240035054A1

公开(公告)日：2024-02-01

申请号：US18267524

申请日：2021-12-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Tae Joo YANG ,  Jihyun SHIM ,  Eun Jung CHOI ,  Byung-sam SON ,  Jae Yong PARK

IPC: C12P19/02 ,  C12N9/24

CPC classification number: C12P19/02 ,  C12N9/2482 ,  C12Y302/01008

Abstract: The present disclosure relates to a modified polypeptide having xylanase activity and the use thereof.

公开(公告)号：US20240218413A1

公开(公告)日：2024-07-04

申请号：US18558904

申请日：2022-03-02

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyung-Chang LEE ,  Jihyun SHIM ,  Jae Yong PARK

IPC: C12P21/06 ,  A01N63/50 ,  A01P1/00 ,  C12N9/36

CPC classification number: C12P21/06 ,  A01N63/50 ,  A01P1/00 ,  C12N9/2462 ,  C12Y302/01017

Abstract: The present disclosure relates to a modified polypeptide with at least one modification selected from the group consisting of deletion, insertion, and substitution of one or more amino acids at positions corresponding to positions 135 and 202 of SEQ ID NO: 1, and methods of use thereof.

公开(公告)号：US20200181661A1

公开(公告)日：2020-06-11

申请号：US16622087

申请日：2018-06-14

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Seon Hye KIM ,  Su Jin PARK ,  Kyoung Min LEE ,  Kyungsu NA ,  Hong Xian LI ,  Hyun-jung BAE ,  Jihyun SHIM ,  Young Lyeol YANG ,  Hye Won UM ,  Hyo Hyoung LEE ,  Min Gyeong KANG ,  Hye Won KIM ,  Byeong Cheol SONG ,  Haena OH ,  Han Hyoung LEE

IPC: C12P13/10 ,  C12P13/00 ,  C07K14/00 ,  C12N15/77

Abstract: The present disclosure relates to a novel polypeptide having an ability to export an ornithine-based product, and a method for producing an ornithine-based product using the same.

公开(公告)号：US20250115888A1

公开(公告)日：2025-04-10

申请号：US18294833

申请日：2022-08-03

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Surin LEE ,  Byung-sam SON ,  Jihyun SHIM ,  Eun Jung CHOI

IPC: C12N9/24 ,  C12P19/02 ,  C12P19/14

Abstract: The present disclosure relates to a modified polypeptide having xylanase activity and use thereof.

公开(公告)号：US20240110170A1

公开(公告)日：2024-04-04

申请号：US18267531

申请日：2021-12-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Tae Joo YANG ,  Jihyun SHIM ,  Eun Jung CHOI ,  Byung-sam SON ,  Jae Yong PARK

IPC: C12N9/24

CPC classification number: C12N9/2482 ,  C12Y302/01008

Abstract: The present disclosure relates to a modified polypeptide having xylanase activity and the use thereof.

公开(公告)号：US20240101977A1

公开(公告)日：2024-03-28

申请号：US18266500

申请日：2021-12-03

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Heeyeong KIM ,  Jihyun SHIM ,  Kyungrim KIM ,  Kwang Woo LEE ,  Woosung CHOI

IPC: C12N9/10 ,  C12N1/20 ,  C12N15/77 ,  C12P13/06

CPC classification number: C12N9/1096 ,  C12N1/20 ,  C12N15/77 ,  C12P13/06 ,  C12R2001/15 ,  C12Y206/01042

Abstract: The present application relates to a novel branched-chain amino acid aminotransferase variant that decreases the amount of by-products generated during the production of L-isoleucine, a polynucleotide encoding the variant, and a vector comprising the polynucleotide, a microorganism comprising the variant, polynucleotide or vector, and a method for producing L-isoleucine using the microorganism.

公开(公告)号：US20230072150A1

公开(公告)日：2023-03-09

申请号：US17784775

申请日：2021-02-10

Applicant: CJ CheilJedang Corporation

Inventor： Jaewon JANG ,  Jihyun SHIM ,  Sang Min PARK ,  Hyun Won BAE ,  Hyo Jeong BYUN ,  Yong Uk SHIN ,  Han Hyoung LEE ,  Boram LIM ,  Moo Young JUNG ,  Yunjung CHOI

IPC: C12P13/08 ,  C12N15/70 ,  C12N15/77 ,  C07K14/34 ,  C12P13/10

Abstract: Provided are a microorganism comprising variant LysE, and an L-amino acid producing method using same. The variant LysE may improve L-amino acid excretion and/or production capacity compared to a wild type.